Clinical trials: Elective Surgical Patients
the Position of Laryngeal Mask Airway
Comparison Between Blind And Ultrasound Guided Laryngeal Mask Airway Insertion
The Proper position of a laryngeal mask airway (LMA) requires confirmation to ensure the adequacy of laryngeal seal and pulmonary ventilation.
- Trial name
- NCT04090944
- Testing
- the fiberoptic laryngoscope (KARL STORZ 11301BN1, Germany) for confirmation of LMA position
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Beni-Suef University
Adult Patients Undergoing Cardiac Surgery, High Bleeding Risks
Transfusion Reduction in High-Bleeding-Risk Cardiac Surgery With Desmopressin
Rationale Bleeding after cardiac surgery is a complication that might result in increased morbidity, mortality, and cost of cardiac surgery by 1.76 (confidence interval (CI), 1.64-1.90) times and a median increase in costs by…
- Conditions
- Adult Patients Undergoing Cardiac Surgery, High Bleeding Risks, Planned Elective Cardiac Surgery Using CPB
- Trial name
- REDES-BLEED (NCT07012837)
- Testing
- Desmopresin
- Where
- Saudi Arabia
- Volunteers
- 112 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Patient Between 1-8 Years Old Undergoing Elective Surgery at Queen Mary Hospital
Comparison of Two Doses of Intranasal Dexmedetomidine as Premedication in Children
Intranasal dexmedetomidine has shown to be an effective sedative when used prior to anaesthetic induction as premedication. 1mcg/kg intranasal dexmedetomidine was used in previous study and it produced satisfactory sedation in…
- Trial name
- NCT01065701
- Testing
- Dexmedetomidine
- Where
- Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Patients in Good Health, Types of General Anesthesia
Toxicogenomic and Immunocytotoxic Effects of Propofol and Isoflurane Anesthetics in Patients Undergoing Elective Surgery
The purpose of this study is to evaluate if the anesthetics propofol and isoflurane can damage DNA, induce apoptosis, change expression of genes related to apoptosis and DNA repair and change cytokines profile in patients…
- Conditions
- Patients in Good Health, Types of General Anesthesia, DNA Damage
- Trial name
- NCT00854178
- Testing
- Comparison of two anesthetic drugs
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Obesity, Obstructive Sleep Apnea
Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35
This study proposes to evaluate the clinical applicability of the ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA) in obese surgical patients undergoing general anesthesia.
- Trial name
- NCT01825278
- Testing
- ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Tufts Medical Center
Cardiac Complication, Perioperative Complication
Trimodal Prehabilitation in Patients Undergoing Elective Surgery
Patients scheduled for elective surgery will undergo 4 week course of trimodal prehabilitation
- Trial name
- NCT05114408
- Testing
- 4 week trimodal prehabilitation course
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Gdansk
Extracorporeal Circulation; Complications, Air Embolism
Comparing Air Embolic Load in Two Venous Cannulation Methods, 40 Patients Undergoing Elective Valve Surgery.
The goal of this single center prospective controlled observational and interventional trial is to investigate and compare origin of air emboli when different venous cannulation methods is used in patients undergoing cardiac…
- Trial name
- NCT05820828
- Testing
- Volume control
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Petronella Torild
Postoperative Acute Kidney Injury, Postoperative Complications
Hypotension Prediction Index-guided Hemodynamic Optimization Trial to Reduce Postoperative Acute Kidney Injury (HYT).
MAIN AIM OF THE STUDY To establish whether hemodynamic management guided by the hypotension prediction index (HPI) guided by the administration of intravenous fluids and vasoactive drugs in patients undergoing elective major…
- Trial name
- HYT (NCT05569265)
- Testing
- Intraoperative hemodynamic management
- Where
- 26 sites in Spain
- Volunteers
- 958 people
- Sponsor
- Maria José Clara Colomina Soler
Patients Ongoing Elective Abdominal Laparoscopy
Laparoscopic Surgery and Abdominal Compliance
The objective of the study is to describe factors influencing abdominal compliance during laparoscopic surgery, including neuromuscular blocking agents (NMBA).
- Trial name
- COELIOCUR (NCT02816567)
- Testing
- propofol, NMBA - cisatracurium, sufentanil
- Where
- France
- Volunteers
- 180 people
- Sponsor
- CHU de Reims
Infrarenal Abdominal Aortic Aneurysm
Arterial Stiffness, Blood Pressure and Cardiac Output Study
Comparison of non-invasively obtained central blood pressure using SphygmoCor and invasively recorded central blood pressure in patients with an AAA that will be treated with EVAR.
- Trial name
- ABC (NCT03469388)
- Testing
- Pulse wave analyses; central blood presaure parameters
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Post-induction Hypotension (PIH)
Preoperative Caval-Aortic Index and Pleth Variability Index for Predicting Post-Induction Hypotension in Colorectal Surgery
This prospective observational study evaluated whether the preoperative caval-aortic index and pleth variability index can predict post-induction hypotension in adult patients undergoing elective colorectal surgery under general…
- Trial name
- NCT07876362
- Testing
- Preoperative Caval-Aortic Index and Pleth Variability Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Perioperative/Postoperative Complications, Risk Factor, Cardiovascular
Myocardial Injury in Noncardiac Surgery in Sweden
The purpose of this multicentre, prospective, observational study is to identify robust biochemical markers that predict adverse cardiovascular outcomes and mortality in patients undergoing major abdominal surgery.
- Trial name
- MINSS (NCT03436238)
- Where
- 7 sites in Sweden
- Volunteers
- 1,269 people
- Sponsor
- Linkoeping University
Propofol, Sevoflurane
Sevoflurane Versus Propofol: Effect on Stress Response
Stress is defined as hormonal and metabolic changes in the biological system that follow any injury. The stress response occurs as a general systemic response to injury and includes a wide range of endocrinological, immunological…
- Conditions
- Propofol, Sevoflurane, Inflammatory Response
- Trial name
- NCT06386965
- Testing
- taking blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Type 2 Diabetes Mellitus (DM), Gastrointestinal Surgery
Preoperative Oral Carbohydrate Loading in Patients With Type 2 Diabetes Undergoing Gastrointestinal Surgery
This study is a single-center randomized controlled trial in adults with type 2 diabetes who are scheduled for elective gastrointestinal surgery.
- Trial name
- NCT07830537
- Testing
- Standard ERAS Fasting and Clear-Fluid Management, Oral Carbohydrate Loading, Intravenous Glucose
- Volunteers
- 126 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Abdominal Surgery
Remote Telemonitoring to Improve Prehabilitation and Surgical Outcomes of Patients Undergoing Elective Abdominal Surgery
There is data confirming that simple tests of physical capability, such as the timed "get-up-and-go" test and the 6-minute walk test, correlate with surgical outcomes.
- Trial name
- NCT03706963
- Testing
- Phone Call
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Washington University School of Medicine
Elective Surgical Patients
Comparison of Glottic Views and Intubation Times in the Supine and 25 Degree Back-up Positions
Our hypothesis is that the view of the glottis may be improved by putting all patients requiring intubation in the ramped or back up position while maintaining the classic sniffing position.
- Trial name
- NCT02934347
- Testing
- 25 degree back-up position
- Volunteers
- 781 people
- Sponsor
- Betsi Cadwaladr University Health Board
Peripheral Vein Cannulation Guided by Ultrasound
Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
This study evaluates two different techniques for peripheral venous cannulation in operating theatre. Ultrasound guided insertion of peripheral cannula in comparison with conventional approach without any ultrasound guidance.
- Trial name
- NCT05119985
- Testing
- Peripheral vein cannulation, Cannulation without ultrasound
- Where
- Czechia
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Hypothermia
National Epidemiologic Survey on the Incidence of Perioperative Hypothermia
Study Objective: to project the incidence of perioperative hypothermia in patients with elective surgery under general anesthesia in China to determine the risk factors associated with perioperative hypothermia.
- Trial name
- NCT02211703
- Where
- China
- Volunteers
- 2,208 people
- Sponsor
- Jie YI
Post-induction Hypotension (PIH), Gastrointestinal Tumor Surgery
Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery
This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid…
- Trial name
- NCT07777159
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Ankara City Hospital Bilkent
Allergy
Penicillin Allergy De-Labelling in Elective Surgical Patients (PADLES)
Penicillin antibiotics are safe and inexpensive, and target selected bacteria rather than killing a broad range. Unfortunately, around 10% of the population are labelled as 'penicillin allergic'.
- Trial name
- PADLES (NCT03607734)
- Testing
- Amoxicillin
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust