Clinical trials: Elective Surgical Patients
Acute Pain, Surgery
Prescribing Vs. Recommending Over-The-Counter (PROTECT) Analgesics for Patients with Postoperative Pain:
This is a research project in which two standard of care practices will be evaluated to examine the difference in outcomes. The goal is to improve patient care and safety.
- Trial name
- PROTECT (NCT05370404)
- Testing
- Prescription by surgical team, Recommendation by surgical team
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Cervical Spine Fusion
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients…
- Trial name
- MCP (NCT05996133)
- Testing
- Bupivacaine Hcl 0.25% Inj, Normal saline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hartford Hospital
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Perioperative/Postoperative Complications, Risk Factor, Cardiovascular
Myocardial Injury in Noncardiac Surgery in Sweden
The purpose of this multicentre, prospective, observational study is to identify robust biochemical markers that predict adverse cardiovascular outcomes and mortality in patients undergoing major abdominal surgery.
- Trial name
- MINSS (NCT03436238)
- Where
- 7 sites in Sweden
- Volunteers
- 1,269 people
- Sponsor
- Linkoeping University
General Anesthesia, Sevoflurane
Efficacy and Safety of Sevofran in Patients Scheduled for Elective Surgery Under General Anesthesia
Sevoflurane is currently being used in more than 100 countries worldwide with an estimated 100 million operations having been performed using sevoflurane as a general anesthetic.
- Conditions
- General Anesthesia, Sevoflurane, Generic Drugs
- Trial name
- NCT01096212
- Testing
- original sevoflurane, generic sevoflurane
- Where
- 2 sites in South Korea
- Volunteers
- 178 people
- Sponsor
- Asan Medical Center
Hypotension on Induction
FloPatch for Prevention of Hypotension After Induction of General Anesthesia
This study is being conducted to find out if a special device called FloPatch™, which sticks to a persons skin and uses ultrasound to check the blood flow in their neck, can tell if someone going to have low blood pressure after…
- Trial name
- HI-CAP (NCT06316817)
- Testing
- FloPatch
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- Mount Sinai Hospital, Canada
This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections
A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients
This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery.
- Trial name
- NCT07562776
- Testing
- Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines., Standard pre operative fasting
- Volunteers
- 144 people
- Sponsor
- Gulab Devi Hospital
Cardiac Disease
Patient Preferences and Experiences of Waiting for Heart Surgery
Waiting for heart surgery could be difficult and anxiety-provoking for some patients. Research suggests that some specific factors (e.g., individual coping strategies, communication with the clinical team, having a more active…
- Trial name
- NCT05996640
- Testing
- This is study does not use an intervention
- Volunteers
- 268 people
- Sponsor
- King's College London
Elective Cardiac Surgical Interventions
Cytokine Removal in Cardiopulmonary Bypass Patients
Cardiopulmonary bypass (CPB) surgery initiates a systemic inflammatory response induced by extrinsic (e.g. anesthesia, contact activation within the extracorporeal circuit, endotoxemia) and intrinsic (e.g.
- Trial name
- CytoSorb (NCT01879176)
- Testing
- CytoSorb
- Where
- Austria
- Volunteers
- 46 people
- Sponsor
- Medical University of Vienna
Staphylococcal Infections
Preoperative Nasal Swabs From Pediatric Patients
We intend to take a nasal swab from each pediatric pre-operative patient in our out-clinic with the intention of looking for a connection between positive operative incisions and a positive nasal swab.
- Trial name
- NCT00646919
- Testing
- Nose swab
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Cardiac Failure, Ventricular Dysfunction
Safety and Efficacy of the Gastric Reactance (XL) in Patients Post-operated of Elective Cardiac Surgery
Evaluate the safety and effectiveness of the XL trend measured by Florence (Critical Perfusion Inc, Palo Alto, California) in the prediction of morbimortality of Mexican patients post-operated of elective cardiovascular surgery.
- Conditions
- Cardiac Failure, Ventricular Dysfunction, Valvular Heart Disease
- Trial name
- NCT03799133
- Testing
- Florence device
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Critical Perfusion Inc.
Venous Thromboembolism
Prevention of Venous Thromboembolism in Patients Undergoing Elective Total Hip Replacement Surgery
The purpose of this study is to examine the superiority of YM150 to the placebo and to evaluate the dose-dependent response of YM150 in patients undergoing elective total hip replacement surgery.
- Trial name
- NCT00913120
- Testing
- YM150, Enoxaparin
- Where
- 16 sites in Japan, South Korea and 2 more
- Volunteers
- 610 people
- Sponsor
- Astellas Pharma Inc
Postoperative Care, Intensive Care
Is There a Benefit of Postoperative ICU Management After Elective Surgery in Critical Ill Patients?
Postoperative care of high risk patients in the Intensive Care Unit (ICU) has for long been considered to be the gold standard of care in terms of reducing perioperative mortality.New evidence from a 7-day cohort study involving…
- Trial name
- NCT03777150
- Testing
- Postoperative care in Intensive care unit (ICU), Postoperative care in standard ward
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Saint Savvas Anticancer Hospital
Arthroplasty, Replacement, Knee, Venous Thrombosis
A Study of BIBR 1048 in Prevention of Venous Thromboembolism in Patients With TKR Surgery.
The goal of this study is to evaluate the comparative efficacy and safety of three different doses ( 110 mg, 150 mg, 220 mg) of BIBR 1048 (Dabigatran etexilate) orally, compared to placebo, in prevention of venous thromboembolism…
- Trial name
- NCT00246025
- Testing
- Dabigatran etexilate
- Where
- 38 sites in Japan
- Volunteers
- 512 people
- Sponsor
- Boehringer Ingelheim
Ambulatory Surgical Procedures, Anxiety Disorders
Educational Video and Peri-operative Anxiety
Preoperative anxiety is a common problem with an impact on surgical outcome, anaesthetic drug dosage and patient's satisfaction. An important component of preoperative anxiety is due to concerns related to anaesthesia.
- Trial name
- NCT03581097
- Testing
- Video Group
- Where
- Switzerland
- Volunteers
- 93 people
- Sponsor
- University Hospital, Geneva
Elective Surgery
Does American Society of Anesthesiologists (ASA) Physical Status Scale Enough in Patients Assessment
American Society of Anesthesiologists (ASA) physical status scale has been used worldwide for assessing the status of patients before operation.
- Trial name
- ASAINPA (NCT00776880)
- Testing
- ASA scale, PPS scale
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Nanjing Medical University
Pain
The Medasense Study
Despite various efforts there is still the need for adequate monitoring of pain and nociception during anesthesia. In a previous protocol the investigators measured pain responses during anesthesia based on single end-points, eg…
- Trial name
- NCT01912118
- Testing
- Propofol, Remifentanil
- Where
- Netherlands
- Volunteers
- 96 people
- Sponsor
- Leiden University Medical Center
Healthy
VASER-Assisted Lipoplasty Compared With Suction-Assisted Lipoplasty
This study is being done to compare two commonly available types of body contouring, VASER-Assisted Lipoplasty (VAL) and Suction-Assisted Lipoplasty (SAL), and to decide if one procedure is preferred by patients and/or surgeons…
- Trial name
- Contra-Lateral (NCT00731354)
- Testing
- Suction-assisted Lipoplasty, VASER-assisted lipoplasty
- Where
- 3 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sound Surgical Technologies, LLC.
Diabetes Mellitus Type 2
Carbohydrate Loading in Type 2 Diabetes Mellitus
The goal of this clinical trial is to learn the effects of preoperative carbohydrate loading on perioperative blood glucose levels and insulin resistance in type 2 diabetes mellitus undergo elective surgery.
- Trial name
- NCT06687811
- Testing
- preoperative carbohydrate loading
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Indonesia
Postoperative Sleep Disturbance, Orthopedic Surgery Patients
Effect of ASMR and White Noise on Sleep Quality in Patients Undergoing Elective Lower Extremity Surgery
This randomized controlled trial aims to evaluate the effects of Autonomous Sensory Meridian Response (ASMR) and white noise on postoperative sleep quality in patients undergoing elective lower extremity surgery.
- Conditions
- Postoperative Sleep Disturbance, Orthopedic Surgery Patients, Sleep Quality
- Trial name
- SLEEP-ASMR (NCT07651228)
- Testing
- ASMR Audio Intervention, White Noise Audio Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- muzeyyen ataseven