Clinical trials: Elective Surgical Patients
Ileostomy - Stoma, Colorectal Surgery
Readmission and Dehydration Prevention in Patients With Elective Ileostomy
The goal of this prospective observational study is to evaluate the adherence to DRIP score calculation and the application rate of each proposed item to prevent dehydration and readmission in patients undergoing ileostomy…
- Conditions
- Ileostomy - Stoma, Colorectal Surgery, Dehydration
- Trial name
- PREDESTO (NCT06824623)
- Where
- 7 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Multidisciplinary Italian Study group for STOmas (MISSTO)
Paediatric Airway
Comparison of Time Taken for Intubation and Cormack Lehane View Between C-Mac With Glidescope Video Laryngoscopy in Paediatric Patients
This study compares the time taken to intubate between Cmac video laryngoscopy with Glidescope video laryngoscopy in paediatric patients aged 3-12 years old.
- Trial name
- NCT04145089
- Testing
- Glidescope video laryngoscopy/ C-MAC video laryngoscopy
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Atrial Fibrillation
Concomitant Epicardial Pulmonary Vein Isolation in Patients With Atrial Fibrillation Undergoing Elective Cardiac Surgery
Recent studies demonstrated that radiofrequency isolation of the pulmonary veins (PVI) is a superior alternative to antiarrhythmic drug therapy in patients with symptomatical paroxysmal atrial fibrillation (AF).
- Trial name
- CONTROL-AF (NCT01360918)
- Testing
- Epicardial pulmonary vein isolation, Usual care
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Medisch Spectrum Twente
Postoperative Delirium, Aging Disorder
Non-pharmacological Prevention of Postoperative Delirium by Occupational Therapy Teams
In the world, 230 million surgeries are performed every year and US data indicates that more than a third of patients who undergo surgery are older than 65 years, in which between 10 and 70% develop postoperative delirium (POD).
- Trial name
- PREPODOT (NCT03704090)
- Testing
- Occupational therapy intervention, Standard non-pharmacological prevention intervention
- Where
- Chile
- Volunteers
- 160 people
- Sponsor
- University of Chile
Colorectal Surgery
NIRF Trial: Near-Infrared Spectroscopy for Intraoperative Restriction of Fluids Trial
The purpose of this study is to evaluate if the InSpectra StO2 Monitor can safely guide the amount of fluid needed during colorectal surgery.
- Trial name
- NIRF (NCT00731978)
- Testing
- Restricted intraoperative fluid management
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Hutchinson Technology Inc
ASA III, Elective Prosthetic Surgery
How to Prevent Post-surgery Infections
Evaluation of the effectiveness in reducing the bacterial load on the skin of bedridden opatients through the use of two different cleaning and washing systems (swash bathing gloves vs pre-soaped sponges).
- Conditions
- ASA III, Elective Prosthetic Surgery, Patient Bedridden After Surgery
- Trial name
- Bundle (NCT07848269)
- Testing
- Swab for cleaning, used as first comparator. For this group we want, during these three days and each day, measure skin pH before and after, Coltural exam before and after and time for cleaning
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Spine Surgery
Preoperative Prevention and Early Rehabilitation for Patients Undergoing Elective Spine Surgery
Aim: The aim is to evaluate the outcome after spine surgery when using an integrated program that combined preoperative prevention and early postoperative rehabilitation compared to the routine procedures.
- Trial name
- NCT00459966
- Testing
- Preoperative rehabilitation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypothermia
National Epidemiologic Survey on the Incidence of Perioperative Hypothermia
Study Objective: to project the incidence of perioperative hypothermia in patients with elective surgery under general anesthesia in China to determine the risk factors associated with perioperative hypothermia.
- Trial name
- NCT02211703
- Where
- China
- Volunteers
- 2,208 people
- Sponsor
- Jie YI
Tracheal Intubation
Assessment of the the ETView Double-lumen Tube
The double tube ETView is particularly innovative as it includes an integrated optical fiber to visualize the carena. This study aims to verify if if its use avoids the requirement of a fibreoptic bronchoscopy.
- Trial name
- ETView1 (NCT02040961)
- Testing
- ETView Double-Lumen Tube
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Hopital Foch
Heart Failure, Hip Fracture
Preoperative Levosimendan and Heart Failure
The purpose of this study is to investigate the safety and efficacy of Levosimendan given preoperative to patients with heart failure undergoing noncardiac surgery.
- Trial name
- PELS (NCT01022983)
- Testing
- Levosimendan
- Where
- 4 sites in Norway, Sweden
- Sponsor
- Sykehuset i Vestfold HF
Cervical Spine Instability
Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
This study was done to compare the ease of tracheal intubation using the conventional C blade and the D blade of CMAC videolaryngoscope in patients undergoing cervical spine surgery.
- Trial name
- NCT05561231
- Testing
- Intubation with C blade, Intubation with D blade
- Where
- India
- Volunteers
- 68 people
- Sponsor
- King Edward Memorial Hospital, Mumbai
Prehabilitation, Malnutrition
Prehabilitation for Colorectal Cancer Patients With Low Functional Capacity and Malnutrition
Despite multi-modal prehabilitation (nutrition, exercise, and psychosocial interventions), 60% of older elective colorectal cancer surgery patients with poor physical function were unable to reach a minimum preoperative 400m…
- Conditions
- Prehabilitation, Malnutrition, Physical Functional Performance
- Trial name
- NCT05999370
- Testing
- Nutrition, Exercise
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McGill University
Anaesthesia, General, Anesthesia, Intravenous
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing…
- Conditions
- Anaesthesia, General, Anesthesia, Intravenous, Ventilation
- Trial name
- NCT02706431
- Testing
- Hyperventilation
- Volunteers
- 31 people
- Sponsor
- Karolinska University Hospital
Reversing Vecuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery, Reversing Rocuronium-Induced Neuromuscular Blockade in Patients Undergoing General Anesthesia Surgery
A Dose-Finding Study of Amogammadex Sodium for Reversing Vecuronium and Rocuronium-Induced Neuromuscular Blockade
Background context: Amogammadex sodium has completed Phase I-III clinical studies in China for reversal of rocuronium-induced blockade. No clinical studies have yet been conducted for vecuronium-induced blockade.
- Trial name
- NCT07595393
- Testing
- Rocuronium (0.6mg/kg), vecuronium bromide (0.1mg/kg)
- Volunteers
- 64 people
- Sponsor
- Amckaus PTY LTD.
Venous Thromboembolism
Rivaroxaban (10mg) Given Once Daily in Patients Undergoing Total Hip Replacement Compared to Enoxaparin
The purpose of this study is to assess if 10 mg BAY 59-7939, taken once daily as a tablet, is safe and prevent blood clot which may form after total hip replacement operation.
- Trial name
- NCT00329628
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 215 sites in United States, Argentina and 26 more
- Volunteers
- 4,541 people
- Sponsor
- Bayer
Obstructive Sleep Apnea
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing
Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications.
- Trial name
- NCT03499132
- Testing
- anesthesia
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Drug Abuse
Drug Abuse Among Elective Surgeries: an Observational Study.
Drug abusers and addicts form a challenge to the anesthetist because of the added potential risks involved in the administration of anesthesia to this subset of patients, including potential unforeseen drug-drug interactions.
- Trial name
- NCT05123521
- Testing
- urine analysis
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Oxidative Stress, Cognition Disorders
The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Objective: The aim of this study was to determine the effect of dexmedetomidine in reducing postoperative cognitive dysfunction (POCD) in cardiac surgical patients which use cardiopulmonary bypass machine (CPB).
- Trial name
- NCT03054857
- Testing
- Dexmedetomidine
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Pain, Anesthesia
Evaluation of the Nociception Guided by NoL Index and PK of Fentanyl in Pediatric Patients Under General Anesthesia
Fentanyl is one of the most common used opioids for analgesia during general anesthesia, however there are few studies that describe the relationship between its pharmacokinetics and pharmacodynamics, especially in the pediatric…
- Conditions
- Pain, Anesthesia, Pediatric ALL
- Trial name
- NoLPedFenta (NCT04786275)
- Testing
- Fentanyl, Tetanic stimulation
- Where
- Chile
- Volunteers
- 25 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Surgery--Complications, Nutrition Aspect of Cancer
Preoperative Oral Nutritional Supplement vs Conventional Dietary Advice in Major Gastrointestinal Surgery
Surgical outcome is associated the nutritional status of the patients. Perioperative nutritional supplement for malnutritional patient were recommended.
- Trial name
- NCT03315195
- Testing
- Oral nutritional supplement (ONS)
- Where
- Thailand
- Volunteers
- 268 people
- Sponsor
- Mahidol University