Clinical trials: Elective Surgical Patients
Anesthesia, Neuromuscular Blockade
Comparing Train-of-Four Recovery in the Adductor Pollicis Versus the Adductor Digiti Minimi in Elective Surgery Patients
The train-of-four (TOF) ratio is a quantitative measure used in anesthesia to assess the degree of neuromuscular blockade induced by neuromuscular blocking agents during surgical procedures.
- Trial name
- NCT06467448
- Testing
- EMG Assessement of Recovery of Neuromuscular Function
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Supraglottic Airway Devices Position
Fiberoptic Bronchoscopy on Supraglottic Airway Devices Position
A comparison of SaCo VLMTM video laryngeal mask airway with the I-gel supraglottic airway during airway management in patients undergoing elective surgery.
- Trial name
- NCT06775184
- Testing
- a native video image system, Fiberoptic bronchoscope
- Volunteers
- 80 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Mental Stress
The Effect of Patient Optimism & Pessimism on Recovery From Elective Cardiac Surgery
Before a heart operation, patient outlook may be either pessimistic or optimistic. Previous research on this topic has focused on patient reported quality of life but has never examined measurable clinical outcomes such as length…
- Trial name
- NCT02955914
- Where
- United Kingdom
- Volunteers
- 419 people
- Sponsor
- Dr Vikki Hughes
Hemodynamic Response to Laryngoscopy and Tracheal Intubation
Hemodynamic Responses to Laryngoscopy and Tracheal Intubation
Laryngoscopy and tracheal intubation lead to tachycardia and hypertension due to increase in the plasma catecholamines subsequent to sympathetic stimulation.
- Trial name
- NCT07783256
- Testing
- ketodex, ketofol
- Volunteers
- 70 people
- Sponsor
- Assiut University
Nutrition Assessment, Nutritional Support
The Effect of Perioperative Nutritional Assessment and Nutritional Support on Clinical Outcomes
It is a study to evaluate the relationship between preoperative nutritional assessment and clinical outcomes and to explore the effect of preoperative nutritional support on clinical outcomes in patients after abdominal operation.
- Conditions
- Nutrition Assessment, Nutritional Support, Clinical Outcomes, General Surgery
- Trial name
- PNAS (NCT03115931)
- Testing
- no intervention
- Where
- China
- Volunteers
- 4,880 people
- Sponsor
- Jinling Hospital, China
Elective Orthopedic Surgery
Efficacy of Propofol or Midazolam Compare to Placebo for Preoperative Medication
The purpose of this research is: To evaluate the sedative (reduces irritability or agitation), anxiolytic (reduces anxiety), and amnesic (produces temporary lack of recall) effects of propofol or midazolam when administered for…
- Trial name
- NCT01976845
- Testing
- Midazolam, Propofol, Saline
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain, Postoperative Nausea and Vomiting
Effectiveness of Low-Dose Ketamine and Intravenous Lidocaine Versus Fentanyl for Postoperative Pain
Background: Rational approaches to perioperative patient management have been used to meet intraoperative analgesic needs and avoid opioid-related adverse effects.
- Trial name
- Vs(versus) (NCT07213687)
- Testing
- Low dose intravenous ketamine
- Where
- Ethiopia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dilla University
Adult Patient Undergoing Elective Surgery With Spinal Anesthesia
Comparison Between Vapocoolant Spray and Eutectic Mixture of Local Anesthetics in Reducing Pain From Spinal Injection
This study aimed to evaluate the effect of vapocoolant spray and EMLA in reducing pain from spinal injection
- Trial name
- NCT03134391
- Testing
- Vapocoolant spray, EMLA
- Where
- Indonesia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Venous Thromboembolism, Arthroplasty, Replacement
Pradaxa (Dabigatran Etexilate) VTE Prevention After Elective Total Hip or Knee Replacement Surgery
an open, prospective, observational study to collect data on safety (major bleeding events) and efficacy (symptomatic venous thromboembolism(VTE)) of a switch from Enoxaparin to dabigatran etexilate in patients with total knee…
- Trial name
- NCT01153698
- Testing
- dabigatran
- Where
- 7 sites in Austria
- Volunteers
- 167 people
- Sponsor
- Boehringer Ingelheim
Chronic Post-operative Pain
Palmitoylethanolamide for Post-operative Pain Prevention
Postsurgical pain becomes chronic when it lasts more then two months after surgery. A neurogenic or neuropathic pathogenesis is hypothesized for this event that reaches high rates after urologic and gynecologic surgeries.
- Trial name
- PEAforCPSP (NCT01491191)
- Testing
- Palmitoylethanolamide
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Acute Pain, Surgery
Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures
The purpose of this study is to evaluate the effect of pharmacogenetics (PGx) guided treatment when implemented into the pre-operative process for patients undergoing bowel surgery, major urologic procedure, or major ventral…
- Trial name
- NCT02605343
- Testing
- NeuroIDgenetix Test Panel
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- AltheaDx
Kinesiophobia
Kinesiophobia, Postoperative Pain, and Early Mobilization After Elective Abdominal Surgery
This study examines the level of kinesiophobia (fear of movement) in patients undergoing elective abdominal surgery and its relationship with postoperative pain severity and early mobilization.
- Trial name
- NCT07834554
- Testing
- Tampa Scale for Kinesiophobia (TSK)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Volkan Gokmen
Coronary Artery Bypass Graft, Cardiopulmonary Bypass
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MDCO-2010 in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery
The purpose of this study is to demonstrate that periprocedural infusion of escalating doses of MDCO-2010 is safe and tolerated in patients undergoing elective CABG surgery, to characterize the single dose pharmacokinetics of…
- Trial name
- NCT01535222
- Testing
- MDCO-2010
- Volunteers
- 32 people
- Sponsor
- The Medicines Company
Elective Surgical Patient, Hypertensive Patients
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
Dexmedetomidine, an alpha-2 adrenergic agonist, has been shown to provide several benefits during endotracheal intubation: 1. _Reduced anxiety and stress_: Dexmedetomidine's anxiolytic and sedative effects help reduce anxiety and…
- Conditions
- Elective Surgical Patient, Hypertensive Patients, Blood Pressure, Hypertensive Elderly Patients
- Trial name
- NCT06712186
- Testing
- Dexmedetomidine Group / Group D
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Postoperative Pain, Lumbar Spine Surgery
Postoperative Pain Monitoring With ANI in Lumbar Spine Surgery
This study aims to compare two different pain management methods in patients undergoing elective lumbar spine surgery. Patients are randomly assigned to receive either an ultrasound-guided erector spinae plane block (ESPB) or…
- Trial name
- SPINE-ANI (NCT07455565)
- Testing
- Erector Spinae Plane Block, Intravenous Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University Hospital
Perioperative/Postoperative Complications, Outcome
Evaluation of BIomarkers for POstoperative Complications in Non-cardiac Surgery Patients
Aim of this study is to evaluate whether the periopertive course is able to predict postoperative complications. Several approaches will be choosed to optimize perioperative risk stratification predicting postoperative…
- Trial name
- NCT03765372
- Where
- Germany
- Volunteers
- 1,598 people
- Sponsor
- Technical University of Munich
Coronary Artery Disease
Dynamic Arterial Elastance for Prediction of Vasopressor Requirement After Anesthesia Induction in Elective On-Pump CABG
This study aims to determine whether dynamic arterial elastance (EaDyn), measured after anesthesia induction, can predict the need for vasopressor treatment in patients undergoing elective on-pump coronary artery bypass graft…
- Trial name
- NCT07871201
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Elzem SEN
Preoperative, Carbohydrate
Preoperative Two Hours Carbohydrate Load On Pediatric Patient Undergoing Elective Surgery
This work evaluated the systemic effect of different preoperative carbohydrate (CHO) loads in pediatrics undergoing elective surgery.
- Conditions
- Preoperative, Carbohydrate, Pediatric, Elective Surgery
- Trial name
- NCT06833671
- Testing
- Apple juice, Anhydrous glucose, Water
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Urologic Diseases, Cardiovascular Diseases
Patient Empowerment for Major Surgery Preparation @ Home
Non-randomized monocentric open cohort study vs historical comparative group testing the efficacy of a multimodal prehabilitation program (based on physical activity, nutritional support and mental preparation) for unfit patients…
- Conditions
- Urologic Diseases, Cardiovascular Diseases, Thoracic Diseases, Orthopedic Disorder
- Trial name
- Paprika (NCT04190719)
- Testing
- multimodal prehabilitation
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Grenoble