Clinical trials: Elective Surgical Patients
Hypertensive Episode
Prevalence of Hypertensive Disease in Patients Presenting for Elective Surgery in the Western Cape, South Africa
Hypertension is a major medical and public health burden throughout the world. It is estimated that 1 in 3 adult South Africans are diagnosed with hypertension, however detailed statistics reflecting the burden of disease are…
- Trial name
- HASS (NCT03157661)
- Where
- 7 sites in South Africa
- Volunteers
- 382 people
- Sponsor
- University of Cape Town
Surgery
Effect of an Anti-spasmodic Suppository to Improve Comfort After Urologic Surgery
This study evaluates the ability of a belladonna and opium suppository given prior to surgery to improve bladder comfort after surgery for patients who are having elective ureteroscopy surgery.
- Trial name
- SPASMS (NCT02291042)
- Testing
- B+O Suppository
- Volunteers
- 50 people
- Sponsor
- Southern New Hampshire Medical Center
Obstructive Sleep Apnea
Semi-up Right Position Study
Our main objective is to perform an explanatory, first stage proof of concept, randomized controlled trial to determine whether a semi-upright patient position versus a supine position while asleep in the postoperative period…
- Trial name
- NCT02152202
- Testing
- Semi-upright position, Supine position
- Where
- 4 sites in Canada
- Volunteers
- 164 people
- Sponsor
- University Health Network, Toronto
Cardiac Surgery, Prehabilitation
Prehabilitation Program for Patients Awaiting Elective Heart Surgery at Increased Risk of Postoperative Complications: Feasibility and Potential Clinical Outcomes
The goal of this study is to learn if an exercise-based prehabilitation program can help people who are waiting for heart surgery and are at higher risk of complications recover better.
- Conditions
- Cardiac Surgery, Prehabilitation, Postoperative Complications
- Trial name
- PRÉAD-CARDIAQU (NCT07144722)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Montreal Heart Institute
Anesthesia
A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery
A multicenter, open, controlled, Phase III clinical study to evaluate the efficacy and safety of Cipepofol injection for general anesthesia in pediatric patients undergoing elective surgery
- Trial name
- NCT06391931
- Testing
- Cipepofol, Propofol
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Mild Cognitive Impairment
Preoperative Cognitive Screening of Surgical Patients 65 Years of Age or Older
The overall objectives of this study are to improve outcomes of surgical patients 65 years of age or older through risk stratification based on preoperative screening of cognition / mental function.
- Trial name
- NCT02570451
- Testing
- Patient Survey, Mini Cog, Independent Activities of Daily Living Score Sheet
- Where
- United States
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anesthesia for Elective Surgery Patients, Anesthesia Brain Monitor
Reevaluation Prediction of the Effect Site Propofol Eleveld Model Using Slow and Fast Induction
Patients ASA1-2, 18 to 70 years old, scheduled for elective surgery with personal conset to participate, will be randomised into two groups using different induction mode.
- Conditions
- Anesthesia for Elective Surgery Patients, Anesthesia Brain Monitor, Pharmacodynamics
- Trial name
- fast or slow E (NCT07237477)
- Testing
- Evaluation of the prediction of from the propofol PKPD model including in TCI pumps using fast (Effect site mode TCI) or slow (plasma TCI mode) induction
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Pablo O. Sepulveda
Perioperative Complication, Cardiovascular Complication
Cardiovascular Outcomes and Mortality in Vascular Surgical Patients
This is a registry-based study of elective vascular surgical patients undergoing intermediate or high-risk vascular surgical interventions at Groote Schuur hospital, a tertiary academic center, over a 12 month period.
- Trial name
- NCT05208957
- Testing
- No intervention
- Where
- South Africa
- Volunteers
- 175 people
- Sponsor
- University of Cape Town
Cataract Surgery, COVID-19
Effect Not Imposing COVID-19 Testing Prior to Elective Cataract Surgery
The world health organization declared corona virus disease (COVID19) a pandemic since march 2020. Since then the future landscape of medical practices and procedures is being heavily shaped by the emergence of this pandemic.
- Trial name
- NCT05217862
- Testing
- PCR for COVID-19 testing
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Surgery, Immune System and Related Disorders
Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery
Over 30 million surgeries are performed annually in the US. Up to 30% of surgical patients experience delayed surgical recovery, marked by prolonged post-surgical pain, opioid consumption, and functional impairment, which…
- Conditions
- Surgery, Immune System and Related Disorders, Preoperative Care, Gastrointestinal Disease
- Trial name
- NCT04498208
- Testing
- Physical Prehabilitation, Stress Reduction Prehabilitation, Cognitive Prehabilitation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
Airway Management
VieScope Versus Direct Laryngoscopic Intubation
Patients requiring endotracheal intubation for elective surgery without expected difficult airway are randomized to be intubated either by a) VieScope or b) conventional direct laryngoscopy.
- Trial name
- VieScOP (NCT04724408)
- Testing
- VieScope, Conventional
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Elective Surgeries
Postoperative Quality of Recovery in Patients Receiving Anaesthesia
The investigator's study is designed to evaluate the recovery of patients receiving anaesthesia for surgeries; in different domains like the physiological, nociceptive, cognitive and emotional to the participants' preoperative…
- Trial name
- NCT03535025
- Where
- Nepal
- Volunteers
- 195 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Rectal Cancer
The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery
Patients' ability to tolerate surgery is associated with physical fitness: less fit patients have an increased rate of death and serious complications following major surgery.
- Trial name
- SRETP (NCT01914068)
- Testing
- Supervised exercise in hospital
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Acute Kidney Dysfunction
Cardiopulmonary-bypass and Reno-protective Effect of Atorvastatin Trial
Acute kidney dysfunction is common after cardiac surgery. While many patients suffer no long-term ill effects from post-operative kidney dysfunction, some require initiation of dialysis therapy that can contribute to long-term…
- Trial name
- CREAT (NCT00910221)
- Testing
- Atorvastatin
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Austin Health
Gut Microbiota, Postoperative Pulmonary Complications
Gut Microbiota and Pulmonary Complications After Non Cardiac Elective Surgery in Elderly Patients
An observational cohort was established using preoperatively collected biospecimens and prospectively ascertained postoperative outcomes.
- Trial name
- NCT06513416
- Testing
- Elective abdominal surgery
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Peking Union Medical College Hospital
Iron Deficiency Anemia
Polyglucoferron Compared to i.v. Ferric Carboxymaltose and Oral Iron Substitution in Preoperative Treatment of Iron Deficiency Anaemia in Patients
Patients with IDA and for whom fast replenishment of iron stores is necessary, e.g. if its not appropriated to postpone surgery, will be identified within 28 to 42 days before surgery.
- Trial name
- IDA-I (NCT04087993)
- Testing
- Polyglucoferron, Ferric carboxymaltose, Ferrous Sulfate
- Where
- Germany
- Sponsor
- Dr. Frank Behrens
Cholecystectomy, Elective Surgery
Comparison Of Dexmedetomidine and Fentanyl In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy.
Compare effects of intravenous dexmedetomidine and fentanyl in attenuation of intubation response in a patient undergoing laparoscopic cholecystectomy.
- Trial name
- NCT04089592
- Testing
- Dexmedetomidine, Fentanyl
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Laparoscopic Colorectal Surgery
HEAT HumiGard Evaluation Study
During long surgical procedures under general anaesthetic, patients' body temperatures sometimes drop below 36°C. This is classified as hypothermia.
- Trial name
- HEAT (NCT04164706)
- Testing
- HumiGard device
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Cardiff and Vale University Health Board
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia with tracheal intubation. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07252921
- Testing
- HRS-9190
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Vascular Surgery
POWER: PrehabilitatiOn Workshop and Mentored Exercise Programme in Patients Having Elective Aortic Aneurysm Repair
Protocol Short Title: POWER Study - PrehabilitatiOn Workshop and mentored Exercise programme in patients having elective aortic aneurysm Repair Population: Patients scheduled for elective repair of aortic aneurysm at St.
- Trial name
- POWER (NCT04169217)
- Testing
- Prehabilitation
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust