Clinical trials: Elective Thoracic Surgery
Mid-line Laparotomies
Analgesia for Mid-line Laparotomies: Thoracic Epidural vs Restus Sheath Analgesia
Midline laparotomies are accompanied by severe postoperative pain. Adequate post-operative pain relief after major abdominal surgery reduces complications (e.g.
- Trial name
- NCT04262622
- Testing
- Group TEA: thoracic epidural analgesia group, Group RSB: rectus sheath block group
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Pain, Postoperative, Pain, Acute
Dexmedetomidine and Morphine as Adjuvants to US Guided Erector Spinae Plane Blocks in Elective Thoracic Surgeries
The aim of this study will be to compare the effects of morphine versus dexmedetomidine when used as adjuvants to local anesthetic (Ropivacaine) in Erector Spinae Plane Block under ultrasound guidance.
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Morphine
- Trial name
- NCT05843344
- Testing
- erector spinae plane block with a combination of ropivacaine and morphine, erector spinae plane block with a combination of ropivacaine and dexmedetomidine, erector spinae plane block with ropivacaine only
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Dr Kassiani Theodoraki
Stroke
Exclusion of the Left Atrial Appendage (LAA) With the LAAx, Inc. TigerPaw System
The dual primary safety and effectiveness outcomes for the use of The TigerPaw System include the rate of device related adverse and serious adverse events and the extent of complete exclusion of the LAA with minimal residual…
- Trial name
- NCT00962702
- Testing
- LAAx TigerPaw System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- LAAx, Inc.
Thoracic Aortic Aneurysm, Respiratory Insufficiency
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
The purpose of this study is to determine whether immunonutrition and pre operative nutrition can reduce lenght of respirator support, lenght of stay in the ICU and incidence of post operative infections
- Trial name
- NCT00339053
- Testing
- Immunonutrition ( Impact)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- St. Antonius Hospital
Elective Open Thoracotomy
Remifentanil Without Muscle Relaxant for Thoracotomy
Although the administration of muscle relaxation is essential standard of care for thoracic procedures, it could cause long-reversal times and postoperative residual curarization (PORC) increasing length of post-anesthesia care…
- Trial name
- NCT02030808
- Testing
- Muscle Relaxants (MR) group, Non- Muscle Relaxants (NMR) group
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Pain, Postoperative, Pain, Acute
Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks
The aim of this study will be to compare the effects of morphine versus ketamine when they are used as adjuvants to the local anesthetic in paravertebral nerve blocks performed with the aid of ultrasound.
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- Annie-Dimitr (NCT04852484)
- Testing
- local anesthetic-morphine, local anesthetic-ketamine, local anesthetic
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Aretaieion University Hospital
Surgery, Thoracic
Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective VATS
The aim of the study is to compare two different locoregional techniques in VATS.
- Trial name
- NCT05798585
- Testing
- ESP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Andrea Saporito
Coronary Artery Disease, Postoperative Complications
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery.
- Conditions
- Coronary Artery Disease, Postoperative Complications, Aortic Valve Stenosis, Mitral Valve Disease
- Trial name
- PREFER-CABG (NCT03574311)
- Testing
- Ferric carboxymaltose, Physiological saline
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- Turku University Hospital
Spontaneous Pneumothorax
Techniques for Lung Deflation With Arndt® Blocker
The use of wire-guided Arndt® endobronchial blocker does not gain widespread acceptance during video-assisted thoracoscopy (VATS) because it takes longer time to collapse the operative lung especially in patients with chronic…
- Trial name
- NCT02030795
- Testing
- Disconnection group, Bronchial Suction group
- Where
- Saudi Arabia
- Volunteers
- 58 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Local Anesthetic Toxicity, Regional Anesthesia Morbidity
Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery
Primary aim: observe the incidence of systemic toxicity from local anesthetic (LAST) after performing fascial blocks in patients undergoing elective cardio-thoracic and abdominal surgery.
- Conditions
- Local Anesthetic Toxicity, Regional Anesthesia Morbidity, Postoperative Pain
- Trial name
- NCT05592691
- Testing
- Fascial block
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Thoracic Anesthesia, Lung Ultrasound
Auscultation, Lus, Fob In Olv (ALFIO)
The study will be to demonstrate that, in patients undergoing elective thoracic surgery, lung ultrasound (LUS) in OR is more sensitive, specific and accurate method than thoracic auscultation, for the evaluation of OLV.
- Conditions
- Thoracic Anesthesia, Lung Ultrasound, Left Double-lumen Tube, Selective Bronchial Intubation
- Trial name
- ALFIO (NCT03912311)
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- University of Parma
Elective Thoracic Surgery, Pulmonary Function
Deep Learning for Preoperative Pulmonary Assessment in Thoracic CT
The trial was designed as a single-centre, non-interventional prospective observational study to utilize deep learning technology combined with computed tomography (CT) images to precisely predict the pulmonary function…
- Conditions
- Elective Thoracic Surgery, Pulmonary Function, Deep Learning
- Trial name
- NCT06477458
- Testing
- Single inspiratory phase computed tomography., Respiratory dual-phase computed tomography.
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University