Clinical trials: Electroencephalographic
Cognitive Deterioration
Objective Measurement of Pain in Individuals With Cognitive Deterioration Utilizing Electroencephalography
This research addresses the challenge of pain assessment in individuals with cognitive deterioration (CD), a common aspect of aging and various neurological conditions.
- Trial name
- NCT06256666
- Testing
- BIS Quantitative EEG
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Delirium
Delirium, Electroencephalographic Alterations and Cortical Spreading Depression (CSD) in Critical Illness
Delirium in the intensive care unit is an acutely developed brain dysfunction affecting up to 80 % of patients. It is associated with significantly increased morbidity and mortality during admission and post-discharge.
- Trial name
- NCT01980251
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Chronic Pain
Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord Injury
The diagnosis of chronic pain currently lacks objective and quantifiable biomarkers. This study aims to observe the EEG characteristics of patients with chronic pain following spinal cord injury and subsequently administer…
- Trial name
- NCT06531837
- Testing
- Esketamine(Continuous infusion), Remifentanil (Target-Controlled Infusion), Flurbiprofen (Single intravenous injection)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Pain Postoperative, Nociceptive Pain
Intraoperative Electroencephalographic Biomarkers of Postoperative Pain
The goal of this study is to explore whether specific intraoperative EEG signals (brain waves or neuronal electrical activity) are associated with the severity of acute postoperative pain.
- Trial name
- NCT06313320
- Where
- 2 sites in Chile
- Volunteers
- 57 people
- Sponsor
- University of Chile
Creutzfeldt-Jakob Disease (CJD) | Prion Disease
CLIME-CJD: A Multimodal Study
Creutzfeldt-Jakob disease (CJD) is a rare and rapidly progressive neurological disorder. This study aims to describe and summarize the key features of CJD by looking back at medical records of patients who were diagnosed with CJD…
- Trial name
- NCT07589283
- Testing
- No Interventions
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Anesthesia
Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
A correlation between the bispectral index values and electroencephalographic patterns at the loss of consciousness (LOC) when using propofol in elderly patients, has not been determined.
- Trial name
- NCT03195530
- Testing
- Propofol
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Post-anesthesia Recovery
Ketamine Effect on Isoflurane Anesthesia
Ketamine effect on isoflurane anesthesia This study is designed to study the effect of ketamine on isoflurane anesthesia. As both drugs are hypnotic and are used to cause sleep during surgery and other painful procedures, it was…
- Trial name
- NCT03290495
- Testing
- ketamine, saline
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Anaesthetic Requirements During Total Hip Arthroplasty
Effects of Combined Pericapsular Nerve Group (PENG) and Lateral Femoral Cutaneous Nerve (LFCN) Blocks on Anaesthetic Requirements and Electroencephalographic Depth of Anaesthesia During Total Hip Arthroplasty: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to evaluate the effects of combined pericapsular nerve group (PENG) and lateral femoral cutaneous nerve (LFCN) blocks on intraoperative anaesthetic consumption and…
- Trial name
- PENG-LFCN-EEG (NCT07903740)
- Testing
- Combined Pericapsular Nerve Group (PENG) and Lateral Femoral Cutaneous Nerve (LFCN) Block, EEG-Guided General Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kocaeli City Hospital
Lumbar Spine Fusion Surgery
Multimodal GA for Lumbar Spine Surgery
To evaluate the effects of multimodal general anesthesia on the recovery profile of elder patients undergoing lumbar spine fusion surgery.
- Trial name
- NCT05247177
- Testing
- dexmedetomidine, ketamine co-administration with sevoflurane for general anesthesia, Conventional general anesthesia by administration of sevoflurane alone
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Postoperative Delirium, Cognitive Function Abnormal
EEG Characteristics and Postoperative Delirium
The goal of this [type of study: observational study ] is to [compare Energy differences in various bands of intraoperative electroencephalogram in elderly patients with postoperative delirium and non delirium.] in [describe…
- Conditions
- Postoperative Delirium, Cognitive Function Abnormal, PSI, Frailty
- Trial name
- NCT06102967
- Testing
- delirium
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhuo Liu
Coronavirus COVID-19, Respiratory Infection
EEG as Predictor of HD-tDCS Effectiveness in Long COVID-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Trial name
- NCT05289128
- Testing
- Experimental group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Paraíba
Surgery, Postoperative Delirium
Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis
Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients.
- Conditions
- Surgery, Postoperative Delirium, Anesthesia, Silent Stroke
- Trial name
- NCT06545786
- Testing
- Intraoperative electroencephalography
- Where
- Russia
- Volunteers
- 265 people
- Sponsor
- Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
Deep Sedation, Mechanical Ventilation
Spectral Edge Frequency From Spectral EEG Analysis to Guide Deep Sedation in the Critical Care Setting (Pilot)
Critically ill patients under mechanical ventilation (MV) have pain, anxiety, sleep deprivation and agitation. The use of analgesics and sedatives drugs (sedoanalgesia) is a common practice to produce pain relief and comfort…
- Trial name
- SEFICU (NCT04026451)
- Testing
- Sedation guided by SEF95 (10-13 Hz) from SedLine® monitor, Sedation guided by SAS scale (1-2), Deep sedation with propofol andfentanyl
- Where
- 2 sites in Chile
- Sponsor
- University of Chile
Sleep Disorder
Safety and Performance Study of the Electroencephalographic Recording Device and Sound Emissions
Safety and performance study of the MemoWave electroencephalographic and sound recording device to increase slow brain waves during sleep to improve memory consolidation in subjects with mild cognitive impairment
- Trial name
- MEMOWAVE (NCT04875442)
- Testing
- Memowave emitting sounds, Memowave not emitting sounds
- Where
- France
- Sponsor
- BioSerenity
Treatment-resistant Depression
Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) I
Our hypothesis is that targeted propofol infusion in treatment-resistant depressed patients will induce slow wave activity during sedation and augment subsequent sleep slow wave activity.
- Trial name
- NCT04680910
- Testing
- Propofol, Electroencephalography (EEG), Slow-Wave Activity
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Washington University School of Medicine
Propofol Overdose, EEG
Dose-response Curves Between Propofol and Intraoperative Electroencephalographic Patterns
In the world, 230 million surgeries are performed per year and a significant part is performed in patients over 65 years of age.
- Trial name
- NCT04345926
- Testing
- Propofol, Electroencephalogram recording
- Where
- 2 sites in Chile
- Volunteers
- 15 people
- Sponsor
- University of Chile
Alzheimer Disease, Lewy Body Dementia (LBD)
The Role of Advanced Electroencephalographic Data as Marker of Pathology and Prognosis in Primary Dementias
The study aims to use advanced brainwave recordings of electroencephalogram (EEG) to understand early signs of Alzheimer's disease (AD) in people with mild memory problems, known as amnestic Mild Cognitive Impairment (MCI).
- Conditions
- Alzheimer Disease, Lewy Body Dementia (LBD), Mild Alzheimer Disease, Frontotemporal Dementia (FTD)
- Trial name
- NCT06826157
- Testing
- Electroencephalogram, 3 Tesla MRI, Apolipoprotein E genetic test
- Where
- Italy
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Encephalopathy, Brain Diseases
EEG Abnormalities as Predictor of Outcome in Pediatric Encephalopathy
This prospective cohort study aims to evaluate the prognostic value of electroencephalographic (EEG) abnormalities in predicting poor clinical outcomes among children with encephalopathy admitted to Assiut University Children…
- Trial name
- NCT07825675
- Volunteers
- 147 people
- Sponsor
- Assiut University
Stroke
Safety and Feasibility of eGlove
The purpose of this study is to measure how cortical signals improve in stroke participants after passive hand stretching therapy from a robotic glove.
- Trial name
- NCT05345301
- Testing
- Event related desynchronization measurement
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Pain
Acute Pain Oscillation in Electroencephalographic Monitoring Under General Anaesthesia
Chronic pain is an undesirable condition that impacts predominantly quality of life at all levels. Chronic pain might occur in healthy young patients when acute postoperative pain is undertreated and persists in time.
- Trial name
- EEGpain (NCT05873894)
- Testing
- EEG
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Hospital General Universitario de Valencia