Clinical trials: Electrolyte Imbalance
Hyperkalemia
Lower vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department
This clinical trial aims to evaluate the safety and efficacy of a lower dose insulin compared to the conventional dose for treating mild to moderate hyperkalemia, a condition characterized by elevated serum potassium levels below…
- Trial name
- IDK+ (NCT06724991)
- Testing
- Lower Dose Therapy, Conventional Dose Therapy
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Hyperparathyroidism, Secondary
Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis
This study is designed to assess the efficacy and safety of etelcalcetide (AMG 416) compared with placebo in the treatment of SHPT in CKD patients receiving hemodialysis.
- Trial name
- NCT01788046
- Testing
- Etelcalcetide
- Where
- 106 sites in United States, Australia and 13 more
- Volunteers
- 515 people
- Sponsor
- Amgen
Alcoholic Liver Cirrhosis, Ascites
Prevention of Decompensation in Liver Cirrhosis
The purpose of this study is to determine whether losartan, an angiotensin II blocker prevents the sodium retention in patients with liver cirrhosis and by that reduces the fluid retention.
- Trial name
- NCT00239096
- Testing
- losartan (drug)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Dehydration, Physical Exertion
Metabolomic Analysis of the Impacts of Hydration Status on Exercise Performance
Kona Deep is bottled water extracted from a depth of 3000 feet off the cost of Kona, Hawaii. Kona Deep claims that this unique source provides water that is "naturally free of pathogens, chemicals and pollutants and rich in…
- Conditions
- Dehydration, Physical Exertion, Salivary Osmolar Concentration, Urinary Osmolar Concentration
- Trial name
- NCT02486224
- Testing
- Kona Deep, Spring Water, Sports Drink
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Primary Adrenal Insufficiency, Ramadan Fasting
Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone.
In primary adrenal insufficiency (PAI), there is a risk of hypoglycemia and dehydration. These risks seem to be increased during intermittent fasting.
- Conditions
- Primary Adrenal Insufficiency, Ramadan Fasting, Prednisolone, Continuous Glucose Monitoring
- Trial name
- NCT07367425
- Testing
- Ramadan fasting
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Hopital La Rabta
Malnutrition Elderly, Kidney Diseases
Methods for Nutrition, Inflammation, Kidney Function, Aging, Body Composition, and Hydration Among Older Patients
The goal of this observational study, is to improve the diagnostic assessment method of malnutrition and kidney diseases, amongst hospitalized and low priority patients, by evaluating modern methodology and biomarkers, with…
- Conditions
- Malnutrition Elderly, Kidney Diseases, Dehydration
- Trial name
- MIKADO (NCT07501195)
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Ove Andersen
Hyponatremia
Establishment of an Algorithm for a Clinical Classfication of Hypoosmolar Hyponatremia
The prospective clinical diagnosis of hyponatremia is often very difficult- but requirement for an appropriate and riskless treatment of hyponatremia.
- Trial name
- CONA (NCT00541944)
- Where
- Germany
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wuerzburg
Osteoporosis, Hypercalcemia
Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine Disorders
Hormones are chemical messengers that help regulate many functions in the body. As women go through menopause, and as men age, levels of certain reproductive hormones change significantly.
- Conditions
- Osteoporosis, Hypercalcemia, Primary Hyperparathyroidism, Adrenal Gland Disease
- Trial name
- NCT07824102
- Where
- Denmark
- Volunteers
- 20,000 people
- Sponsor
- Martin Blomberg Jensen
Hyponatremia, Premature
Early Sodium Intake in Preterm Newborns
Hyponatremia is a common complication among preterm infants, renal losses of sodium contribute to the development of hyponatremia in preterm newborns. Sodium imbalances impact in newborns outcome.
- Trial name
- NCT04035564
- Testing
- Sodium < 1mEq/kg/day, Sodium 5mEq/kg/day
- Where
- Mexico
- Volunteers
- 52 people
- Sponsor
- Hospital del Niño "Dr. Federico Gomez Santos"
Acute Gastroenteritis, Dehydration
Continuous Enteral Rehydration by Nasogastric Tube With ORS in Children With Acute Gastroenteritis
When oral rehydration is impossible, enteral rehydration via the nasogastric route has been the recommended method of rehydration since 2008 by ESPGHAN ( European Society for Paediatric Gastroenterology Hepatology and Nutrition…
- Trial name
- GEA (NCT04555200)
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Brest
Thirst, Water-Electrolyte Imbalance
Effects of Glucagon Like Peptide 1 (GLP-1) Analogues on Fluid Intake
The aim of this study is to elucidate whether GLP-1 analogues influence not only appetite but also thirst perception. It is hypothesized that GLP-1 analogues reduce fluid intake in healthy volunteers compared to Placebo.
- Trial name
- GATE (NCT03141632)
- Testing
- Dulaglutide
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hyponatremia
Targeted Correction of Plasma Sodium Levels in Hospitalized Patients With Hyponatremia
Hyponatremia is the most common electrolyte disorder with a prevalence of up to 30% in hospitalized patients. While treatment of acute hyponatremia with severe clinical symptoms due to cerebral edema is undisputed and…
- Trial name
- HIT (NCT03557957)
- Testing
- Targeted correction of plasma sodium levels, Standard care
- Where
- 9 sites in Croatia, Germany and 3 more
- Volunteers
- 2,278 people
- Sponsor
- University Hospital, Basel, Switzerland
Dehydration, Urinary Infections
GEL-AID: Safe and Effective Hydration for Institutionalized Older Adults
The objective of this clinical trial is to assess whether hydration with gelled water (GEL-AID) can improve fluid intake and reduce cases of dehydration, as well as the incidence of urinary and respiratory infections in…
- Conditions
- Dehydration, Urinary Infections, Respiratory Infections, Daily Fluid Intake
- Trial name
- NCT07381881
- Testing
- GEL-AID, Usual Care
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
DiGeorge Anomaly, Complete DiGeorge Anomaly
Phase I/II Thymus Transplantation With Immunosuppression #950
The study purpose is to determine if cultured thymus tissue implantation (CTTI) (previously described as transplantation) with tailored immunosuppression based on the recipient's pre-implantation T cell population is a safe and…
- Conditions
- DiGeorge Anomaly, Complete DiGeorge Anomaly, Complete Atypical DiGeorge Anomaly, Complete DiGeorge Syndrome
- Trial name
- #950 (NCT00579527)
- Testing
- Cultured Thymus Tissue for Implantation (CTTI), Cultured Thymus Tissue Implantation and Parental Parathyroid Transplantation, Blood Draw
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
End Stage Renal Disease
Comparison of Serum Calcium Level Between Preoperative Vitamin D and Non-vitamin D Regimen of Total Parathyroidectomy in End-stage Renal Failure Patients in Rajavithi Hospital
This Research is compare about IV Calcium between end-stage renal failure patients who take vitamin D and non-vitamin D preoperative parathyroidectomy
- Trial name
- NCT04967469
- Testing
- Calcitriol, Alfacalcidol 0.5 MCG Oral Capsule
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Stroke, Dehydration
BUN/Cr-based Hydration Therapy to Improve Outcomes for Dehydrated Patients With Acute Ischemic Stroke.
The investigators' preliminary findings suggest that providing patients with acute ischemic stroke hydration therapy on the basis of their presenting BUN/Cr ratio may help reduce the occurrence of stroke-in-evolution(SIE) and…
- Trial name
- HYDO (NCT02099383)
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 244 people
- Sponsor
- Chang Gung Memorial Hospital
Dehydration
Microcirculation in Dehydrated Older Patients
This proof-of-concept study examines whether 1) sublingual measurement in dehydrated old patients is feasible, 2) frailty and incompliance in old, awake patients affects video-quality, 3) dehydration impacts microcirculation This…
- Trial name
- MicroCirc (NCT04261374)
- Testing
- Measurement of sublingual microcirculation
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Fluid and Electrolyte Imbalance
RL Versus Glucose Saline in Cancer Patient Undergoing Major Surgeries and Its Impact on Electrolytes, GLC & pH
To compare two electrolytes maintenance in perioperative period in children undergoing major surgeries on perioperative change in pH,lactate,sodium and glucose level
- Trial name
- NCT05810662
- Testing
- Lactated ringer and dextrose 5%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Kidney Diseases, Hyponatremia
Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function
A study to compare a conivaptan PK in subjects with mild or moderate kidney function impairment to subjects with normal kidney function after a 48-hour continuous infusion of conivaptan.
- Trial name
- NCT00887627
- Testing
- conivaptan hydrochloride
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cumberland Pharmaceuticals
Lipodystrophy, Obesity
Hemoglobin Level, Coagulopathy Profile and Electrolyte Balance
What is Impact of Amount Versus Surface Area of Liposuction on Haematological Parameters, Coagulopathy Profile and Electrolyte Balance? Liposuction involves the creation of extensive subsurface trauma, comparable in many respects…
- Trial name
- NCT04656054
- Testing
- liposuction
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alaa Hassan M. Elhawary