Clinical trials: Electrolyte Imbalance
Secondary Hyperparathyroidism, Renal Insufficiency, Chronic
Effectiveness and Safety of IV Zemplar in Patients on Hemodialysis and With Secondary Hyperparathyroidism Using iPTH/100 as Initial Dose
The purpose of this study is to observe the effectiveness and safety of the use of a low initial dose regime (iPTH/100) in chronic kidney disease patients with secondary hyperparathyroidism (PTH>300pg/mL) and that require…
- Conditions
- Secondary Hyperparathyroidism, Renal Insufficiency, Chronic, Parathyroid Hormone, Hemodialysis
- Trial name
- NCT00891813
- Testing
- Zemplar (paricalcitol)
- Where
- 3 sites in Peru
- Volunteers
- 100 people
- Sponsor
- Abbott
Dehydration
Effect of Different Fluid Ingestion Rate on Post-exercise Rehydration
The purpose of the present study is to investigate the effect of different rate of fluid consumption on post-exercise rehydration.
- Trial name
- NCT04155372
- Testing
- Different Fluid Ingestion Rate
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Hyponatremia, Dilutional Hyponatremia
Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia
The purpose of this study is to determine if hospitalized patients with symptomatic hyponatremia treated with tolvaptan are in the hospital for less time than patients treated with fluid restriction.
- Conditions
- Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
- Trial name
- SALACIA (NCT01227512)
- Testing
- tolvaptan, Fluid Restriction
- Where
- 56 sites in United States
- Volunteers
- 124 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Hyperkalemia, Chronic Kidney Disease (Stage 3-4)
AK+ Guard™ Pilot Study in Chronic Kidney Disease: Outpatient Diagnostic Accuracy and Remote Monitoring
The goal of this observational pilot study is to evaluate the investigational AK+ Guard™ software as a medical device (SaMD) for detection of moderate to severe hyperkalemia (serum potassium (K+) ≥ 6.5 mmol/L) in adults with…
- Trial name
- NCT07210021
- Testing
- AK+ Guard™ ECG Application
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AccurKardia, Inc.
Colorectal Cancer
C-Reactive Protein and Sodium in Predicting Anastomotic Leakage
Anastomotic leakage is serious morbidity that can develop in patients operated on for colorectal cancer and can reach potentially life-threatening dimensions.
- Trial name
- NCT04717648
- Testing
- Biochemical test
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Tepecik Training and Research Hospital
Hyponatremia
Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function
In this study patients with hyponatremia, defined as a serum sodium < 126 mmol/L on admission to the hospital will be tested for muscular power by use of a hand grip dynamometer, for cognitive function by use of the…
- Trial name
- NCT04020926
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Bürgerspital Solothurn
Hyperkalemia
A Comparative Study of ZG-801 and Placebo in Patients With Hyperkalemia
The purpose of this study is to evaluate the superiority of ZG-801 to placebo in Japanese hyperkalemia patients whose serum potassium value becomes normal in the Run-in period by comparing the change in the value at the…
- Trial name
- NCT04955678
- Testing
- Calcium, hydrolysed divinylbenzene-Me 2-fluoro-2-propenoate-1, 7-octadiene polymer sorbitol complexes
- Where
- Japan
- Volunteers
- 85 people
- Sponsor
- Zeria Pharmaceutical
SIAD - Syndrome of Inappropriate Antidiuresis, Hyponatremia
Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Hyponatremia is a common electrolyte imbalance which often results from hormonal disregulation. The study aims to investigate whether the apelin hormone, which plays a role in regulating salt and water balance in the body, can be…
- Trial name
- ESCAPE (NCT06277336)
- Testing
- Apelin Low Dose, Apelin High Dose, Selected Apelin Dose
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Antidiuretic Hormone, Inappropriate Secretion
Samsca Post-marketing General Drug Use-results Survey in Patients With Hyponatremia in SIADH
The purpose of this study is to confirm the safety of tolvaptan in patients with hyponatremia in syndrome of inappropriate antidiuretic hormone secretion (SIADH) in Japan
- Trial name
- NCT04790175
- Testing
- Tolvaptan (SAMSCA)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Hyperkalemia, Hemodialysis
Hyperkalaemia Prevalence, Recurrence and Treatment in Haemodialysis
The objective of this study is to evaluate the prevalence and recurrence of Hyperkalaemia (HK) in Chinese HD patients and to understand the treatment pattern of HK in China.
- Conditions
- Hyperkalemia, Hemodialysis, Water-Electrolyte Imbalance
- Trial name
- PRECEDE-K (NCT04799067)
- Testing
- observational study
- Where
- 12 sites in China
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Hyperkalemia
Safety & Efficacy of Zirconium Silicate in Mild to Moderate Hyperkalemia
Acute Phase: It is hypothesized that ZS (zirconium silicate) is more effective than placebo control (alternative hypothesis) in lowering S-K levels in subjects with S-K between 5.0 - 6.5 mmol/l versus no difference between ZS and…
- Trial name
- NCT01737697
- Testing
- Zirconium silicate (acute phase), Zirconium silicate (subacute phase)
- Where
- 44 sites in United States, Australia
- Volunteers
- 754 people
- Sponsor
- ZS Pharma, Inc.
Hyperkalemia
Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns
The purpose of this study is to find out whether there is a correlation (link) between the level of potassium in blood samples drawn from a vein and those drawn from a heel stick in infants scheduled for elective surgery.
- Trial name
- PS (NCT01349218)
- Testing
- Blood sample drawn from a vein, Blood sample drawn from a heel stick
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Dehydration, Diabetes Mellitus, Type 2
INDIGO-2: The Effect of High Water Intake on Glucose Regulation in Low-drinkers
Previous studies have indicated increased vasopressin due to hypertonic saline infusion impairs glucose regulation. The current study will examine the effect of low water intake on glucose regulation.
- Trial name
- INDIGO-2 (NCT04076995)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hyponatremia, Hypernatremia
Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery
The goal of this clinical trial is to determine if isotonic or hypotonic fluids are more effective in maintaining serum sodium levels in neonates undergoing maintenance fluid therapy post-surgery.
- Conditions
- Hyponatremia, Hypernatremia, Postoperative Care in Neonates, Edema
- Trial name
- NCT06484608
- Testing
- Isotonic Saline with Dextrose
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Hypocalcemia, Thyroid Diseases
Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia?
The investigators are performing this study to determine if supplementation with calcium and calcitriol (vitamin D) before surgery decreases the rate of hypocalcemia (low calcium) after surgery.
- Trial name
- NCT03869398
- Testing
- Tums, Calcitriol
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Hyperkalemia, Chronic Kidney Disease(CKD)
Prevalence and Risk Factors of Hyperkalemia in Non-Dialysis Chronic Kidney Disease Patients in Community
The goal of this observational study is to investigate the prevalence and risk factors of hyperkalemia in community-based non-dialysis chronic kidney disease (CKD) patients. The main questions it aims to answer are: 1.
- Trial name
- NCT06940414
- Testing
- No Intervention
- Where
- China
- Volunteers
- 1,890 people
- Sponsor
- Xiujuan Zang
Head and Neck Cancer
Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients
The goal of this research study is to learn if home-use of devices to identify dehydration risk, when added to standard care, will help to lower hospitalizations and emergency room visits (and related costs) in patients with head…
- Trial name
- NCT02253238
- Testing
- Quality of Life Survey, Health Management Surveys, Monitoring Devices
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- M.D. Anderson Cancer Center
Dehydration in Children, Dehydration
The Impact of Brief One-time Education and Coach Encouragement on Hydration Status in Child Judo Athletes
Due to the lack of any comparative study related to effect of different hydration processes, this study aimed to compare the effectiveness of coach encouragement and hydration education in maintaining hydration status in child…
- Trial name
- NCT06992817
- Testing
- Hydration-Coach Encouragement, Short Hydration Informative Session
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Hyponatremia, Accidental Falls
Hyponatremia in the Prevention of Hospitalized Patients Falls
Cross ecological quasi-experimental study to assess effectiveness of early intervention in the diagnosis and treatment of hyponatremia in the prevention of hospitalized patients´ falls.
- Trial name
- PRECAHI (NCT03265691)
- Testing
- Early detection and treatment of hyponatremia, No Intervention (SOC)
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Mª del Carmen Lobo Rodríguez