Clinical trials: Elevated Blood Sugar
Post-Prandial Hyperglycemia, Post-Prandial Hypoglycemia
Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy
The study will be conducted in two phases; an in-patient meal study phase (Phase I) and an outpatient home study (Phase II). The two phase study design is chosen to enhance safety by testing the Afrezza Closed-Loop (CL) system in…
- Trial name
- NCT03234491
- Testing
- DiAS, Afrezza low dose, Afrezza high dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Diabetes, Prediabetic
Sleep Effectiveness and Insulin and Glucose Homeostasis
The purpose of this study is to examine the influence of sleep effectiveness on glucose and insulin metabolism in health and disease (prediabetes and type two diabetes).
- Conditions
- Diabetes, Prediabetic, Prediabetes, Glucose Intolerance
- Trial name
- NCT01887691
- Testing
- eszopiclone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Dehydration, Seizure
Point of Care Device Use in the Pediatric Emergency Department
To compare the effect of "point-of-care" (POC) analysis of blood work with traditional laboratory methods on length of stay in a pediatric emergency department (PED).
- Conditions
- Dehydration, Seizure, Gastroenteritis, Hyperglycemia
- Trial name
- NCT00285285
- Testing
- Point of Care Device; i-Stat Analyzer
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Mellitus, Type 2, Diet, Healthy
CTSI Pilot: Improving Adherence to Diabetic Diet
425 million adults live with diabetes worldwide, and the prevalence of Type 2 diabetes is rising. Dietary approaches are recommended for weight control and diabetes management, but modern environments, characterized by plentiful…
- Conditions
- Diabetes Mellitus, Type 2, Diet, Healthy, Pre-diabetes
- Trial name
- NCT04051008
- Testing
- Online - use of online grocery shopping platform, Default - use of online grocery shopping platform with default shopping carts
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- State University of New York at Buffalo
Diabetes Mellitus, Type 2, Hyperglycemia
Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 Inhibitors
This clinical trial investigates the effects of adding different diabetes medications to patients with type 2 diabetes who are currently being treated with DPP4 inhibitors.
- Conditions
- Diabetes Mellitus, Type 2, Hyperglycemia, Insulin Resistance
- Trial name
- NCT07108985
- Testing
- Sitagliptin 100 mg, Sitagliptin 100 mg + Dapagliflozin 10 mg, Sitagliptin 100 mg + Dapagliflozin 10 mg + Lobeglitazone 0.5 mg
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Isolated Impaired Fasting Glucose
Low-calorie Diet in Isolated Impaired Fasting Glucose
This study aims to evaluate the preliminary efficacy of a low-calorie diet (LCD) intervention in addressing the underlying pathophysiological abnormalities and improving fasting hyperglycemia among individuals with isolated…
- Trial name
- NCT06451055
- Testing
- Low-calorie diet, Routine dietary and physical activity habits
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Type 2 Diabetes
Family Health Team High-Intensity Interval Training
With the rapid shift to virtual care, this pilot study aims to determine the feasibility of prescribing low-duration, interval-based training through virtual care.
- Trial name
- FHT HIIT (NCT04109235)
- Testing
- High-Intensity Interval Training Physical Activity (PA) Advice, Population-Based Physical Activity (PA) Advice
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Pre Diabetes
Therapeutic Intervention of Eriocitrin in the Reduction of Hyperglycemia in Pre-diabetic Individuals
Supplementation with citrus bioflavonoids (hesperidin, naringin, diosmin and eriocitrin, among others) has been associated with an improvement in the glycidic and lipid profile, reduction of insulin resistance and systemic…
- Trial name
- NCT03928249
- Testing
- Eriocitrin
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- São Paulo State University
Endocrine Disease, Diabetes
Mifepristone Effects on Glucose Intolerance in Obese/Overweight Adults
Background: Metabolic syndrome is a name given to a group of factors that tend to occur together. These risk factors include central obesity (extra weight around the middle of the body) and high blood pressure and blood sugar…
- Trial name
- NCT01419535
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Impaired Glucose Tolerance
Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT)
The researchers will investigate whether exercise could provide positive effects on general brain functions in elderly people with impaired glucose tolerance.
- Trial name
- NCT01219231
- Testing
- Exercise
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Charite University, Berlin, Germany
Metabolic Disturbance, Glucose Intolerance
A Nutrient Cocktail to Protect Against Physical Inactivity
This experiment consists on a 20-day reduction in daily step in free-living active individuals to induce physical inactivity. This will be used to test the efficacy of the anti-oxidant cocktail we aim to test as a new…
- Conditions
- Metabolic Disturbance, Glucose Intolerance, Physical Inactivity, Glucose Metabolism Disorders
- Trial name
- NCT03313869
- Testing
- XXS-2A + Omega-3 + Vitamin E + Selenium, control diet
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre National d'Etudes Spatiales
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Pre-Diabetes, Weight, Body
Prevention of Progression of Prediabetes, Obesity and CV Risk
The investigators are studying how to help people with prediabetes (Pre-DM) and obesity. The goal is to use new and affordable treatments to bring blood sugar levels back to normal and help participants to lose weight.
- Conditions
- Pre-Diabetes, Weight, Body, Cardiovascular Diseases
- Trial name
- Pre-DM (NCT06446531)
- Testing
- Rybelsus Tablet, Jardiance 25Mg Tablet, Metformin
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pre-diabetes, Lifestyle Risk Reduction
Evidence-based Intervention for Diabetes Prevention
The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention…
- Conditions
- Pre-diabetes, Lifestyle Risk Reduction, Diet Prevention of Metabolic Diseases
- Trial name
- EID (NCT07443995)
- Testing
- Adapted diabetes prevention program, App based support, Patient education materials
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- New York University
Overweight and Obesity
The Effect of Exercise and/or Diet on Health Related Parameters
The study evaluates the effect of exercise and/or diet during on body weight, body composition and health related blood parameters.
- Trial name
- NCT04100356
- Testing
- Exercise, Normal Diet, LCHF Diet
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- Atlantis Medical University College
Risk Factor, Cardiovascular, Physical Activity
Exercise Effects on Appetite-regulating Hormones and Cardiovascular Risk Factors
The aim of this study is to examine the effect of a single bout of moderate exercise, standardized breakfast and buffet meal on appetite-related hormones, type two diabetes and cardiovascular risk factors with a comparison…
- Conditions
- Risk Factor, Cardiovascular, Physical Activity, Pre-diabetes
- Trial name
- NCT03698786
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kingston University
Type 2 Diabetes, Pre-diabetes
Nutri Diet Goal Setting Software Pilot Trial
The investigators will conduct a pilot cluster randomized trial of Nutri, a clinical decision support software to support collaborative diet goal setting in primary care.
- Conditions
- Type 2 Diabetes, Pre-diabetes, Metabolic Syndrome
- Trial name
- NCT05436041
- Testing
- Collaborative Diet Goal Setting Clinical Decision Support
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Texas at Austin
Metabolic Syndrome, Impaired Glucose Tolerance
11ß-HSD1 and Metabolic Syndrome
The purpose of this study is to determine whether the insulin sensitizing effects of rosiglitazone were accompanied by changes in 11ß-HSD1 expression and activity in different tissues.
- Trial name
- NCT00370305
- Testing
- rosiglitazone
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Type 2 Diabetes
Combination of Sulfonylureas and Insulin Glargine Outpatient Therapy for Unstable Diabetes and Impending DKA
The purpose of this study is to compare two simple and safe emergency department discharge therapy for Type 2 Diabetes patients with severe hyperglycemia and with no indications for inpatient admission.
- Trial name
- NCT00732524
- Testing
- Glipizide, Glipizide and Glargine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Cook County Health
Healthy Diet, Postprandial Hyperglycemia
Effect of the Consumption of Alcohol-free Beers With Different Carbohydrates Composition on Postprandial Metabolic Response
The overall objective of this study is to explore the glycemic index and glycemic load induced by an alcohol-free beer with modified composition (including almost full fermentation of carbohydrates and the addition of…
- Trial name
- NCT04790877
- Testing
- Sub-study 1, Sub-study 2
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
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