Clinical trials: Elevated Blood Sugar
Pre-Diabetes
Designer Functional Foods on Parameters of Metabolic and Vascular in Prediabetes
This is a multi-site, double-blind, randomized, controlled food intervention study being conducted at the Canadian Centre for Agri-Food Research in Health and Medicine (CCARM) in Winnipeg and the Mayo Clinic, Rochester, MN, to…
- Trial name
- PREFFER-2014 (NCT02400450)
- Testing
- Functional Ingredient Group, Control Ingredient Group
- Where
- 2 sites in United States, Canada
- Sponsor
- University of Manitoba
Pre Diabetes
Nasturtium (Tropaeolum Majus L) Intake and Biochemical Parameters in Pre-diabetic Subjects in Bogota Colombia
Brassicaceae plant family have a high content of bioactive compounds such as e.g. glucosinolates (GSLs) and isothiocyanates (ICTs) associated, recently, with diabetes prevention.
- Trial name
- NCT05346978
- Testing
- Nasturtium (Tropaeolum majus)
- Where
- Colombia
- Volunteers
- 10 people
- Sponsor
- Javeriana University
Stress Hyperglycemia
Exenatide for Stress Hyperglycemia
Stress hyperglycemia is a common phenomenon in cardiac surgery that concerns diabetic and non diabetic patients. It has been shown that perioperative hyperglycemia is an independent risk factor of postoperative mortality and…
- Trial name
- ExSTRESS (NCT01969149)
- Testing
- Exenatide, Insulin
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sleep Disorder, Pre Diabetes
Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes
Recruitment strategies comparing different strategies.
- Conditions
- Sleep Disorder, Pre Diabetes, Obstructive Sleep Apnea
- Trial name
- NCT03984058
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Time Restricted Eating, Obstructive Sleep Apnea
Time Restricted Eating in Sleep Apnea
Obstructive sleep apnea (OSA) is a highly prevalent disorder that is associated with both cardiovascular and metabolic dysfunction, such as hypertension, increased blood glucose levels and diabetes, obesity, and nonalcoholic…
- Trial name
- TERESA (NCT06047496)
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Diabetes, Hyperglycemia
Pivotal Study of the Intravenous Blood Glucose (IVBG) System, In-Clinic Setting
The purpose of this study is to evaluate safety and accuracy of the IVBG System (the "System") when used to track blood glucose in insulin treated subjects with diabetes mellitus in an in-clinic setting for up to 72 hours (per…
- Trial name
- NCT00925080
- Testing
- IVBG
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- DexCom, Inc.
Hyperglycaemia, Kidney Transplantation
Continuous Glucose Monitoring (CGM) After Kidney Transplantation
This study examines glucose levels measured by continuous glucose monitoring (CGM) in the immediate period following kidney transplantation among recipients with diabetes, without diabetes, and with pre-diabetes.
- Trial name
- CGM-KTx (NCT06675903)
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- Bo Feldt-Rasmussen
Pre-diabetes
Motivational Instant Messaging and E-diabetes Prevention Programme for High Risk of Type 2 Diabetes
The overall aim of this feasibility trial is to assess the effectiveness of a wearable technology and an e-diabetes prevention programme delivered via a smartphone application, including motivational messaging, in reducing weight…
- Trial name
- NCT02919397
- Testing
- Wearable technology, Diabetes Prevention Programme educational material, Motivational messaging
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Diabetes Mellitus, Type 1
Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial
The ATTEMPT (Adolescent Type 1 diabetes Treatment with SGLT2i for hyperglycEMia \& hyPerfilTration Trial) is a multi-center, double-blinded, randomized, placebo-controlled trial to evaluate the effect of treatment with…
- Trial name
- ATTEMPT (NCT04333823)
- Testing
- Dapagliflozin 5mg
- Where
- 3 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- The Hospital for Sick Children
Autoantibody Positive, Non-diabetic Relatives at Risk for Type 1 Diabetes
Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
The study will determine whether the anti-CD3 monoclonal antibody, teplizumab, can help to prevent or delay the onset of type 1 diabetes (T1D) in relatives determined to be at very high risk for developing the disease.
- Conditions
- Autoantibody Positive, Non-diabetic Relatives at Risk for Type 1 Diabetes, High Risk, Impaired Glucose Tolerance
- Trial name
- NCT01030861
- Testing
- Teplizumab
- Where
- 19 sites in United States, Canada and 1 more
- Volunteers
- 76 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hypoglycemia, Hyperglycemia
Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response
The aim of this study is to Measure the effect on gene expression in leukocytes from a meal rich in oat bran Investigate the postprandial glucose, insulin and triglyceride responses after intake of meals containing fiber from…
- Trial name
- NCT01005342
- Testing
- Oat bran, Spray-dried oat drink, Rye bran
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Lund University
Impaired Glucose Tolerance
The Role of Pulsatile Insulin Secretion (A Study Investigating the Effects of Partial Pacreatectomy on Glucose Metabolism)
The purpose of this study is to examine changes in sugar metabolism that may occur in subjects who have previously had part of their pancreas removed due to a benign lesion.
- Trial name
- Pilot OGTT (NCT00841867)
- Testing
- All subjects will undergo a 120 minute Oral Glucose Tolerance Test at study visit 2.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes Mellitus, Type 2
Improvement of Hyperglycemia/Diabetes in Patients to Improve Safety
The goal of this project is to bring together staff and clinicians from Northwestern University/Northwestern Medical Group/Northwestern Memorial Hospital as well as patients and caregivers to assess and redesign the…
- Trial name
- NCT06096311
- Testing
- Interviews
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Prediabetes, Impaired Glucose Tolerance
Step Up For Health Study: A Pedometer and Website Intervention in Those With Prediabetes
This study will examine whether a physical activity program, specifically increasing walking steps, offered over the internet is able to increase physical activity in adults with prediabetes.
- Trial name
- NCT05412264
- Testing
- Website intervention
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Gestational Diabetes Mellitus, Intrauterine Hyperglycemia
Wenzhou Gestational Diabetes Cohort
The Wenzhou Gestational Diabetes Cohort (WGDC) is a prospective cohort study among women with gestational diabetes mellitus (GDM) during pregnancy and their offspring living in Wenzhou, China.
- Conditions
- Gestational Diabetes Mellitus, Intrauterine Hyperglycemia, Birth Outcome, Adverse, Nutrition, Healthy
- Trial name
- WGDC (NCT05794152)
- Testing
- Standardized breakfast, Standardized snack, Standardized lunch
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Westlake University
Glucocorticoid Induced Hyperglycemia
Liraglutide Efficacy on Glucocorticoid Induced Hyperglycemia in Patients High Risk for Diabetes
Glucocorticoids therapy exposes the patient to an increased risk for diabetes morbidity. However, there is no proven preventive therapy.
- Trial name
- NCT02016846
- Testing
- Liraglutide
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Rabin Medical Center
Type 1 Diabetes, Hypoglycemia
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents
Objective: to gain experience in children and younger adolescents with in-home use of an algorithm that will dose insulin to minimize projected hyperglycemia overnight in addition to suspending the pump if hypoglycemia is…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Hyperglycemia, Artificial Pancreas
- Trial name
- PHM3 (NCT02714972)
- Testing
- Hyperglycemia Minimization Algorithm
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Jaeb Center for Health Research
Gestational Diabetes
Postpartum Glycemia in Women At Risk for Persistent Hyperglycemia
GDM is characterized by decreased insulin sensitivity, decreased insulin secretion, or a combination of both. Women with GDM are at significant risk for overt T2DM later in life, and postpartum insulin sensitivity and secretion…
- Trial name
- NCT04521712
- Testing
- 2-hour 75-g oral glucose tolerance test and Dexcom G6 Pro continuous glucose monitor
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Hyperglycemia Steroid-induced, Insulin Resistance, Diabetes
Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia
Glucocorticoids are known to cause an increase in insulin resistance, leading to hyperglycemia, in both diabetic and non-diabetic patients.
- Trial name
- NCT03511521
- Testing
- NPH Insulin, glargine, Insulin Aspart
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Northwestern University
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