Clinical trials: Elevated Blood Sugar
Pre-diabetes, Diabetes
Immediate and Long-term Induction of Incretin Release by Artificial Sweeteners 1
Epidemiological data suggest, that not only sugar-based, but also artificially sweetened soft drinks may play a role in the development of diabetes.
- Trial name
- ILIAS-1 (NCT02459535)
- Testing
- oral stimulation glucose, oral stimulation saccharin, oral stimulation aspartame
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Glucose Intolerance
C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance
The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose…
- Trial name
- NCT00589355
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Yale University
Endocrine and Metabolic Secondary Hypertension
Sacha Inchi Oil Supplementation in 3Hs
The objective of this study is to evaluate the effect of Sacha Inchi Oil supplementation among the 3Hs patients.
- Trial name
- NCT04920825
- Testing
- Sacha Inchi Oil softgel supplement, Corn oil softgel
- Where
- Malaysia
- Volunteers
- 54 people
- Sponsor
- Universiti Sains Malaysia
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
A diagnosis of gestational diabetes mellitus (GDM)has significant implications for the future health of the mother. GDM is often the culmination of years of unrecognized and unmodified diabetes risk factors that lead to overt and…
- Conditions
- Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus, Metabolic Syndrome, Impaired Glucose Tolerance
- Trial name
- NCT01234649
- Testing
- Metformin XR plus liraglutide
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Woman's
Anemia, Iron Deficiency, Hyperglycemia
Prevalence of Hyperglycemia and Anaemia in Elective Surgical Patients
The study is a prospective, observational study of adult, non-cardiac, non-obstetric, elective surgical patients conducted over a period of one week.
- Trial name
- EPIC-1 (NCT03318055)
- Where
- 6 sites in South Africa
- Volunteers
- 343 people
- Sponsor
- University of Cape Town
Cystic Fibrosis, Diabetes
The Effect of Combination Lumacaftor and Ivacaftor on Markers of Hyperglycemia
The purpose of this research study is to find out if the combined therapy lumacaftor-ivacaftor affects glycemia in patient with cystic fibrosis.
- Trial name
- NCT02858843
- Testing
- lumacaftor-ivacaftor
- Volunteers
- 1 people
- Sponsor
- Massachusetts General Hospital
Pre Diabetes
Effect of Eriocitrin Supplementation in Subjects With Intermediate Hyperglycemia
First, it will be evaluated whether supplementation of eriocitrin reduces hyperglycemia and insulin resistance, significantly reducing the risk of diabetes.
- Trial name
- NCT03215043
- Testing
- Eriocitrin
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Thais Cesar
Non Communicable Diseases, Blood Pressure
Evaluation of the Ambuja Cement Foundation Noncommunicable Disease Program in Bathinda District of Punjab, India
This is an academic evaluation of a program being implemented by the Ambuja Cement Foundation (ACF). The aim of the evaluation is to determine the effect of the ACF noncommunicable disease (NCD) program on (1) fasting blood…
- Conditions
- Non Communicable Diseases, Blood Pressure, Behavior, Health, Blood Glucose, High
- Trial name
- NCT04827615
- Testing
- Ambuja Cement Foundation's Non Communicable Disease Program
- Where
- India
- Volunteers
- 11,322 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Ketosis, Postprandial Hyperglycemia
Pre-meals of 3-hydroxybutyrate in Type 2 Diabetes
Hyperglycemia following meals in patients with type 2 diabetes mellitus (T2DM) is a common problem. Recently, our group found that oral consumption of the ketone metabolite, 3-hydroxybutyrate (3-OHB), effectively stimulates…
- Conditions
- Ketosis, Postprandial Hyperglycemia, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- PreKetone (NCT05581043)
- Testing
- 3-hydroxybutyrate (3-OHB)
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Chronic Obstructive Pulmonary Disease, Hyperglycemia
Insulin Therapy in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations
The purpose of this study is to determine the effect of preventing hyperglycaemia in patients admitted to hospital with acute exacerbations of chronic pulmonary disease.
- Trial name
- NCT00467636
- Testing
- Blood glucose monitoring, Insulin Glulisine
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- The Royal Bournemouth Hospital
Diabetes Mellitus
Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes
The purpose of this study is to determine if restoring normal metabolic function in patients with either type I or type II diabetes can improve the impact of the consequences of diabetic complications specifically on the wide…
- Trial name
- NCT01029444
- Testing
- Pulsatile Intravenous Insulin Therapy (Humulin, Humulog, Novolog )
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida Atlantic University
Hyperglycemia
Metabolic Effects of High-amylose Wheat-based Rusks.
Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based rusks in overweight subjects.
- Trial name
- NCT02702934
- Testing
- Test meal
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Impaired Glucose Tolerance, Myocardial Infarction
Assessment of an Alpha-glucosidase Inhibitor to Block Cardiac Events in Patients With MI and IGT
The purpose of this study is to evaluate whether an alpha-glucosidase inhibitor, a drug for the suppression of postprandial hyperglycemia, could reduce the recurrence of myocardial infarction in patients with impaired glucose…
- Trial name
- NCT00212017
- Testing
- voglibose, diet and exercise therapy
- Where
- Japan
- Volunteers
- 3,000 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Hyperinsulinism, Diabetes
Bionic Pancreas in Children With Hyperinsulinism and Post-Pancreatectomy Diabetes
This is a pilot study designed to determine if the bihormonal bionic pancreas provides improved blood glucose control, compared to the current standard of care, in individuals with hyperinsulinism who developed diabetes after…
- Conditions
- Hyperinsulinism, Diabetes, Pancreatic Diseases, Pancreatectomy; Hyperglycemia
- Trial name
- NCT03303196
- Testing
- Bihormonal Bionic Pancreas
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Prediabetes
Evaluation of Chiglitazar Sodium With Lifestyle Intervention for Reversing Prediabetes
This multicenter, randomized, double-blind, placebo-controlled trial aims to evaluate the efficacy and safety of Chiglitazar Sodium combined with lifestyle intervention for reversing prediabetes to normal glucose metabolism.
- Trial name
- NCT07558525
- Testing
- Chiglitazar sodium
- Where
- 30 sites in China
- Volunteers
- 472 people
- Sponsor
- Second Xiangya Hospital of Central South University
Hyperglycemia, Postoperative Complications
Intensive Insulin Therapy as Therapeutic Strategy for Non-diabetic Hyperglycemia After Surgery in ICU
The current study hypothesizes that the use of Intravenous intensive insulin therapy (IV-IIT) may be beneficial than IV conventional insulin therapy (IV-CIT) for improving the outcome of non-diabetic surgical patients had…
- Conditions
- Hyperglycemia, Postoperative Complications, Insulin Resistance
- Trial name
- NCT04554615
- Testing
- Insulin
- Where
- Saudi Arabia
- Volunteers
- 86 people
- Sponsor
- Tanta University
Critical Illness, Hyperglycemia
Comparing Two Ways of Controlling Blood Sugar With Insulin in Patients Admitted to the Intensive Care Unit
The purpose of this study is to determine if there is any difference between two ways of controlling blood sugar with insulin. In patients admitted to the intensive care unit, blood sugar levels often rise due to the stress of…
- Trial name
- NCT00166491
- Testing
- Insulin
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Mayo Clinic
Pre-Diabetes
BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes
This is a single-centre, 16-week, randomized, double-blind, placebo-controlled, 3-treatment arm pilot study to evaluate the efficacy and safety of BTI320 in the treatment of high risk subjects with pre-diabetes.
- Trial name
- NCT02358668
- Testing
- BTI320
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Pre-diabetes
Screening and Understanding of the Pre-diabetes: DECODIAB
The main objective of the study is to understand the pathophysiological mechanisms involved in switching from pre-diabetes to type 2 diabetes and to identify new biomarkers of type 2 diabetes risk in the population of patients…
- Trial name
- DECODIAB (NCT01739868)
- Testing
- Biopsies of muscular and fat tissue
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Nantes University Hospital
Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations
Background: Type 2 diabetes mellitus is a main risk factor for cardiovascular disease and heart failure, in part due to diabetic cardiomyopathy.
- Conditions
- Type 2 Diabetes Mellitus, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Familiar Hypocalcuric Hypercalcemia, Healthy Volunteers
- Trial name
- RISC_7T (NCT02023489)
- Testing
- 1H/ 13C and 31P Magnetic Resonance Spectroscopy, Meal Tolerance Test, Hyperglycemic-hyperinsulinemic clamp
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
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