Clinical trials: Elevated Blood Sugar
Acute Pancreatitis (AP), Diabetes Mellitus
Hyperglycemia and Acute Pancreatitis
The goal of this observational study is to learn about post-acute pancreatitis diabetes mellitus (PPDM-A). The main questions it aims to answer are: 1. What are the clinical characteristics of PPDM-A? 2.
- Trial name
- NCT06590233
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Changzheng Hospital
Aerobic Exercise, Hyperglycemia
Hyperglycemia and Exercise.
This study will determine whether exposure to short-term high blood glucose levels impairs exercise-induced adaptations in glucose tolerance, and whether the pattern of high blood glucose levels plays a role.
- Conditions
- Aerobic Exercise, Hyperglycemia, Glucose Metabolism Disorders (Including Diabetes Mellitus)
- Trial name
- GlucotoxEx (NCT03284216)
- Testing
- Steady-state hyperglycemia, Fluctuating hyperglycemia, Exercise
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Pregnancy Preterm, Glycemic Control
Metformin to Treat Corticosteroids-induced Hyperglycemia
Antenatal corticosteroids, particularly, betamethasone is routinely administered to pregnant women at risk for preterm delivery to improve neonatal outcomes.
- Conditions
- Pregnancy Preterm, Glycemic Control, Corticosteroids Induced Hyperglycemia
- Trial name
- NCT04332393
- Testing
- Metformin
- Where
- 4 sites in Israel
- Volunteers
- 187 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Insulin Sensitivity, Healthy Adult
Diaplex and Glycemic Control
The goal of this 16-week double-blind, placebo-controlled pilot study is to determine whether daily Diaplex supplementation improves insulin sensitivity and glycemic control in adults with elevated blood glucose levels, while…
- Trial name
- NCT07711587
- Testing
- Diaplex
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Standard Process Inc.
Critical Illness, Hyperglycemia
Tight Versus Liberal Blood Glucose Control in Adult Critically Ill Patients
Critically ill patients usually develop hyperglycemia, which is associated with an increased risk of morbidity and mortality. Controversy exists on whether targeting normal blood glucose concentrations with insulin therapy…
- Trial name
- TGC-fast (NCT03665207)
- Testing
- Insulin
- Where
- 4 sites in Belgium
- Volunteers
- 9,230 people
- Sponsor
- KU Leuven
Trauma, Stress Induced Hyperglycemia
Stress Induced Hyperglycemia In Trauma
The clinical relevance of the observed stress induced hyperglycemia in trauma patients remains unclear. The earlier studies suggested the implications of cytokines in stress induced hyperglycemia and the outcomes after trauma.
- Conditions
- Trauma, Stress Induced Hyperglycemia, Diabetes Mellitus
- Trial name
- SIHG (NCT02999386)
- Where
- Qatar
- Volunteers
- 300 people
- Sponsor
- Hamad Medical Corporation
Glycemic Control, Insulin
Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia
The role of ultralong insulin in the control of the blood glucose level in diabetic patients is well known, the current study will discuss the role of ultralong insulin in controlling of hyperglycaemia in critical illness defined…
- Conditions
- Glycemic Control, Insulin, Critical Illness
- Trial name
- NCT06178874
- Testing
- Insulin Glargine, Insulin Degludec, Insulin regular
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Type 2 Diabetes
Effect of Bydureon on Carotid Atherosclerosis Progression in Type 2 Diabetes Mellitus
Investigators will be determining whether a once weekly injectable medication Bydureon versus placebo is able to reduce the development of atherosclerosis.
- Trial name
- NCT02162550
- Testing
- Bydureon
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Phoenix VA Health Care System
Type 1 Diabetes
Reactive Oxygen Species in the Pathogenesis of Diabetic Complications
Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy and incipient nephropathy in these models.
- Trial name
- NCT00703989
- Testing
- benfotiamine, α-lipoic acid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Burns, Hypoglycemia
Computer Decision Support to Achieve Glycemic Control in the ICU
This study is intended to fill the knowledge gap regarding the burn population with research that achieves scientific merit. we will determine the effectiveness of the computer decision support system (CDSS) to facilitate glucose…
- Trial name
- EndoTool (NCT00589589)
- Testing
- Endo Tool
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- United States Army Institute of Surgical Research
Hypoglycemia Hyperglycemia
Pediatric Critical Illness Hyperglycemia and Glycemic Control Registry
The objective in this project is to assemble a consortium of pediatric critical care centers of varying size, acuity, and composition to evaluate our glycemic control protocol on at least 250 children with hyperglycemia in…
- Trial name
- NCT01116674
- Where
- 3 sites in United States
- Volunteers
- 206 people
- Sponsor
- Indiana University
Prediabetes
Cocoa and Metabolic Health in Prediabetes
The purpose of this study is to determine the impact of consuming cocoa on blood glucose levels, glucose metabolism, and other markers of pre-diabetes in overweight and/or obese individuals.
- Trial name
- NCT02203240
- Testing
- Cocoa
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Polytechnic Institute and State University
Diabetes Mellitus, Type 2
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS)
The purpose of this study is to compare the benefits and risks of lixisenatide (AVE0010) used as 2-step initiation regimen and 1-step initiation regimen in Japan, over a period of 24 weeks of treatment, followed by an extension…
- Trial name
- GETGOAL-MONO (NCT00905255)
- Testing
- Lixisenatide (AVE0010), Pen auto-injector
- Where
- Japan
- Volunteers
- 69 people
- Sponsor
- Sanofi
Hypertension
Salt Loading and Thiazide Intervention Study
The investigators of this study propose to examine the relationships between STK39 (Serine Threonine Kinase 39) genotypes and responses to salt loading and to thiazide diuretics, hydrochlorothiazide.
- Trial name
- SALTI (NCT00896389)
- Testing
- Salt loading, Hydrochlorothiazide (HCTZ)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Type1diabetes, Depressive Symptoms
Type 1 Diabetes and Depression: Role of Brain Glutamate
The goal of this study is to examine the effect of chronic and acute hyperglycemia in type 1 diabetes mellitus (T1DM) on brain glutamate levels using magnetic resonance spectroscopy (MRS), and associations of brain glutamate with…
- Conditions
- Type1diabetes, Depressive Symptoms, Major Depressive Disorder
- Trial name
- NCT05355285
- Testing
- Glucose Clamp
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Overweight/Obesity, Insulin Resistance
Efficacy of Hydroxycinnamates and Beta-glucans as a Dietary Tool Against Obesity (OBHEALTH)
The study aimed at assessing the effect of a decaffeinated green coffee extract, rich in hydroxycinnamates, oat beta-glucans or the combination of both bioactive compounds on overweight/obese subjects with hyperglycemia.
- Trial name
- OBHEALTH (NCT05009615)
- Testing
- Green coffee extract, Beta glucan, Green coffee + beta-glucan
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Type 2 Diabetes
Lifestyle Control of Postprandial Hyperglycemia
Large spikes in blood glucose experienced after meals in people with type 2 diabetes are known to damage blood vessels. Low carbohydrate high fat diets and exercise can improve blood glucose control in people with type 2 diabetes…
- Trial name
- NCT02683135
- Testing
- High-carbohydrate diet, Low-carbohydrate diet, Low-carbohydrate diet with post-meal walking
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of British Columbia
Hyperglycemia
Continuous Glucose Monitoring in Critically Ill Surgical Patients
The specific aim of this study is to identify the degree of correlation between real time subcutaneous glucose monitoring and intermittent glucose monitoring using capillary glucose samples, arterial blood samples and venous…
- Trial name
- NCT01108640
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Diabetes Type 2, Hyperglycaemia (Diabetic)
Effect of Hyperglycaemia and Moxifloxacin on QTc Interval in T2DM
Diabetes is a significant risk factor for sudden cardiac death, with the QTc interval on electrocardiograms (ECGs) often prolonged in diabetic patients due to factors such as hyperglycaemia and insulin resistance.
- Conditions
- Diabetes Type 2, Hyperglycaemia (Diabetic), QT Interval, Variation in, Torsades de Pointes
- Trial name
- NCT07014735
- Testing
- glucose, moxifloxacin
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Richmond Pharmacology Limited
Diabetes
Life Style Modifications Prevents Type 2 Diabetes in Asian Indians
Three year prospective randomised controlled trial in IGT subjects to study the effect of metformin and lifestyle modification in preventing the conversion to diabetes
- Trial name
- NCT00279240
- Testing
- Metformin
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.V. Hospital for Diabetes
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.