Clinical trials: Elevated Intracranial Pressure
Traumatic Brain Injuries, Intracranial Hypertension
Effectiveness of Surgical Procedures for Acute Cranial Expansion in Traumatic Brain Injury
Traumatic brain injury (TBI) patients often exhibit an increase in their intracranial volume due to blood collection or brain tissue edema.
- Trial name
- E-SPACE-TBI (NCT06776614)
- Testing
- Decompressive Craniectomy, Expansion Craniotomy
- Volunteers
- 292 people
- Sponsor
- Meditech Foundation
Intracranial Hypertension, Acute Brain Injury
Non-Invasive Triage for Intracranial Hypertension in Prehospital Care
This study tests whether two non-invasive tools can help paramedics detect dangerously high pressure inside the skull in patients with a sudden brain injury, such as stroke or head trauma, before they reach the hospital.
- Conditions
- Intracranial Hypertension, Acute Brain Injury, Stroke, Traumatic Brain Injury
- Trial name
- B4C-APH (NCT07747636)
- Testing
- Brain4care non-invasive intracranial pressure monitor, Optic nerve sheath diameter ultrasound
- Volunteers
- 180 people
- Sponsor
- Juliana Caldas
Intracranial Hypertension, Traumatic Brain Injury
Invasive Versus Non-Invasive Intracranial Pressure-Guided Management in Neurosurgical Patients
Raised intracranial pressure (pressure inside the skull) is a serious complication for patients with brain injuries, strokes, or tumors. Managing this pressure is critical to prevent further brain damage.
- Conditions
- Intracranial Hypertension, Traumatic Brain Injury, Subarachnoid Haemorrhage (SAH), Intracerebral Haemorrhage
- Trial name
- NCT07853963
- Testing
- External Ventricular Drain (EVD) Placement and ICP Monitoring, Optic Nerve Sheath Diameter (ONSD) Ultrasonography
- Where
- Nepal
- Volunteers
- 40 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
Increased Intracranial Pressure
The Value of Doppler Study of Central Retinal Artery in Diagnosis of Increased ICP
The purpose of this study is to evaluate the diagnostic value of central retinal artery Doppler study in case of increased intracranial pressure.
- Trial name
- NCT05891678
- Testing
- doppler study of central retinal artery
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Inas Ahmed Sayed Ammar
Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension
Bleeding Intracerebral Hemorrhage With Early Invasive Intracranial Pressure Monitoring Trial
Spontaneous cerebral hemorrhage (SICH) is a hemorrhage caused by the rupture of a blood vessel within the brain parenchyma that is non-traumatic.
- Conditions
- Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension, Monitoring, Critical Care
- Trial name
- BIATICH (NCT05593380)
- Testing
- Parenchymal Intracranial pressure monitor, Treatment based on clinical and imaging observations
- Where
- 17 sites in China
- Volunteers
- 193 people
- Sponsor
- Xiangya Hospital of Central South University
Intracranial Pressure Increase
Intra-operative Evaluation of the External Ventricular Drain Catheter Position With Structured Light for Patients (Bullseye EVD)
The placement of external ventricular drainage (EVD) is a life-saving procedure used to relieve high pressures in the brain. Often performed at the bedside, a small tube (catheter) is inserted into one ventricle of the brain to…
- Trial name
- NCT05931991
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Intracranial Hypertension
The Use of Near Infrared Spectroscopy (NIRS) to Estimate Intracranial Pressure (ICP)
The aim of this study is to determine whether we can predict the intracranial pressure using near infra-red spectroscopy
- Trial name
- NCT01850069
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Brain Injuries, Intracranial Hypertension
Prospective Evaluation of the Non-invasive ICP HeadSense Monitor in TBI Patients Undergoing Invasive ICP Monitoring
Patients with severe traumatic brain injury (TBI) are admitted to the intensive care unit (ICU). Under certain condition (such as a impaired consciousness) the intracranial pressure (ICP) is measured.
- Trial name
- NCT02773862
- Testing
- HS-1000
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- HeadSense Medical
ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter
Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes.
- Conditions
- ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter, Intracranial Hypertension
- Trial name
- NCT06367868
- Testing
- After 5 ml CSF Drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
Sodium Lactate, Intracranial Hypertension
Sodium Lactate and Brain Relaxation (LSD)
Resection surgery of brain tumors by craniotomy requires efficient brain relaxation intraoperatively in order to avoid injuries caused by the brain retractors (such as ischemic-reperfusion and cerebral oedema).
- Conditions
- Sodium Lactate, Intracranial Hypertension, Brain Relaxation
- Trial name
- LSD (NCT04488874)
- Testing
- Sodium Lactate, Mannitol 20% Infusion
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon