Clinical trials: Embryo Implantation
Infertility
Predictive Value of Endometrial Cytokines in Endometrial Implantation in Cases of Intracytoplasmic Sperm Injection
For all women immediately after ovum retrieval from 80 women undergoing IVF, intra uterine salin flushing will be analyzed using a multiplex immunoassay for soluble regulators of implantation, namely Interleukin (IL)-1b, Tumor…
- Trial name
- NCT02854514
- Testing
- Aspiration of endometrial secretion
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Benha University
Infertility
Atosiban in Women With Previous Implantation Failure and Abnormal Uterine Contractions
This study aims to evaluate the efficacy of atosiban in patients with previous pregnancy failure and abnormal uterine contractions during the peri-embryo transfer period in assisted reproductive technology.
- Trial name
- NCT07185230
- Testing
- Atosiban
- Where
- China
- Volunteers
- 792 people
- Sponsor
- Northwest Women's and Children's Hospital, Xi'an, Shaanxi
Dental Implantation
Evaluation Of The Effect Of Surface Properties On The Stabılıty Of The Different Implants
This randomised clinical study aims to evaluate different surfaced implants (alkali-modified surfaced implants or sand-blasted surfaced implants) stability with resonance frequency analysis(RFA).
- Trial name
- Surface (NCT03915509)
- Testing
- Evaluation of the effect of surface properties on the stability of the different implants with resonance frequency analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Aortic Stenosis, Gut Microbiome
Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis
This study investigates the impact of transcatheter aortic valve implantation (TAVI) on the composition and function of the gut microbiota in patients with severe aortic valve stenosis.
- Conditions
- Aortic Stenosis, Gut Microbiome, Gut Microbiota, TAVI
- Trial name
- GUT-TAVI (NCT07052071)
- Testing
- TAVI
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Hippocration General Hospital
Implant Complication, Periimplant Infection
The Effect Of Photobiomodulation On Dental Implant Survival
Dental implants offer a high success rate as the most up-to-date treatment method for replacing lost teeth. However, whilst implants have emerged as the ideal treatment for tooth loss, the incidence of postoperative…
- Conditions
- Implant Complication, Periimplant Infection, Periimplant Bone Loss
- Trial name
- NCT07636265
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance
Safety and Performance of Motiva® Sizers
The Motiva® Sizer clinical study is a four-year, multicenter, post-marketing, and cohort study, designed to confirm the safety and performance of Motiva® Sizer in breast augmentation or reconstruction procedures.
- Conditions
- Breast Implant; Complications, Breast Implantation; Methods, Safety and Performance, Mammaplasty, Breast Reconstruction
- Trial name
- NCT06274736
- Testing
- Motiva Sizer
- Where
- Costa Rica
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
CIED-related Infections
Antimicrobial Strategy for Device Implantation
Infections associated with cardiovascular implantable electronic devices (CIEDs) represent one of the major postoperative complications in interventional cardiology.
- Trial name
- NCT07158502
- Testing
- TauroPace Cohort
- Volunteers
- 1,000 people
- Sponsor
- University of Calabria
Infertility, Genetic Disease
Microfluidic Chip vs Density Gradient Centrifugation on the Euploidy Rate of Pre-implantation Genetic Testing
Infertile women attending for PGT at the Centre of Assisted Reproduction and Embryology, Queen Mary Hospital and Kwong Wah Hospital will be recruited during ovarian stimulation for IVF.
- Conditions
- Infertility, Genetic Disease, Chromosomal Rearrangement, Aneuploidy
- Trial name
- NCT06023472
- Testing
- microfluidic chip, density gradient centrifugation
- Where
- China
- Volunteers
- 318 people
- Sponsor
- Professor Ernest Hung-Yu Ng
Cataract, Intraocular Lens Complication
Functional IOL Implantation in Patients With Epiretinal Membrane
We have designed this prospective study to evaluate macular involvement and epiretinal membrane (ERM) grading by OCT in eyes with ERM and to compare clinical outcomes after implantation of Enhance IOL with standard monofocal IOL…
- Conditions
- Cataract, Intraocular Lens Complication, Epiretinal Membrane
- Trial name
- NCT06719739
- Testing
- Intraocular lens implantation
- Where
- 2 sites in China
- Volunteers
- 90 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Infertility, Female
Effect of Oxytocin Antagonists on Implantation Success Rates of Frozen-thawed Embryo Transfer
Uterine contraction has a negative impact on implantation and pregnancy rates. Inhibition of oxytocin receptors decreases uterine contraction frequency both on pregnant and non-pregnant women.
- Trial name
- NCT03904745
- Testing
- Atosiban
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cochlear Trauma, Vestibular Disorder
Vestibular Function in Cochlear Implants
The objective of this study is to identify possible preoperative risk factors including genetic background and to suggest the optimal test battery of vestibular function in cochlear implant recipients
- Conditions
- Cochlear Trauma, Vestibular Disorder, Deafness, Bilateral
- Trial name
- NCT05795530
- Testing
- cochlear implantation
- Where
- Czechia
- Volunteers
- 57 people
- Sponsor
- Charles University, Czech Republic
Congestive Heart Failure
The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices
The purpose of this study is to obtain data or information on how blood clotting factors are activated during open heart surgery.
- Trial name
- NCT01481012
- Where
- 13 sites in United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac Arrhythmias
EluPro Antibiotic-Eluting BioEnvelope Registry
A Multi-Center Registry Study Evaluating Participants Who Receive EluPro Antibiotic-Eluting BioEnvelope During CIED Implantation
- Trial name
- NCT06854081
- Testing
- EluPro Antibiotic-Eluting BioEnvelope
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Elutia Inc.
Sensorineural Hearing Loss, Vestibular Hypofunction
Optimizing Cochlear Implant Laterality in Patients With Unilateral Vestibular Weakness
In patients with symmetric hearing loss who meet traditional cochlear implant candidacy criteria yet demonstrate pre-operative unilateral vestibular weakness, the choice of which ear to implant may impact their post-operative…
- Trial name
- NCT07452653
- Testing
- Ipsilateral cochlear implantation in patients with unilateral vestibular hypofunction, Contralateral cochlear implantation in patients with unilateral vestibular hypofunction
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Aortic Valve Stenosis
Engager Direct Aortic Clinical Study
To confirm the safety and performance of the Medtronic Engager™ Transcatheter Aortic Valve Implantation System via direct aortic approach.
- Trial name
- NCT01789567
- Testing
- Engager™ aortic valve
- Where
- 6 sites in Czechia, Germany and 1 more
- Volunteers
- 20 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF)
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation require treatment with different antithrombotic drugs.
- Conditions
- Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation, P2Y12 Inhibitor
- Trial name
- MATRIX-2 (NCT05955365)
- Testing
- P2Y12 inhibitor, Aspirin, DOAC
- Where
- 15 sites in Belgium, France and 7 more
- Volunteers
- 3,010 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Facial Wrinkles
Multicenter Study of the Safety and Effectiveness of Dermal Filler, Belotero®.
This was a study to find out how an investigational product, Belotero, compares to a second product in people with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00876265
- Testing
- Belotero, Zyplast
- Where
- 6 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Birth Rate, Embryo Implantation
EFFects of Thrombophilia on the Outcomes of Assisted Reproduction Technologies
Both hereditary and acquired thrombophilia have been associated with recurrent miscarriage and pregnancy complications. Thrombophilia could favor the development of thrombosis of the maternal vasculature and obstacle…
- Conditions
- Birth Rate, Embryo Implantation, Reproductive Techniques, Thrombophilia
- Trial name
- NCT02407730
- Where
- Italy
- Volunteers
- 687 people
- Sponsor
- G. d'Annunzio University
Premature Ovarian Insufficiency, Intrauterine Adhesion
Application of Platelet-rich Plasma (PRP) in Reproductive Medicine
Female fertility is affected by many factors, such as ovarian function, fallopian tube patency, uterine environment, and mental state, among which the ovaries and endometrium are more important.
- Conditions
- Premature Ovarian Insufficiency, Intrauterine Adhesion, Poor Ovarian Response, Repeated Implantation Failure
- Trial name
- NCT06645379
- Testing
- Platelet-Rich Plasma (PRP) Injections
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Idiopathic Parkinson's Disease (PD)
MER Versus MRI Guidance DBS in Parkinson's Disease
Most leading academic centers including Baylor College of Medicine (BCM) perform deep brain stimulation surgery in the awake patient using microelectrode recording to guide final electrode placement.
- Trial name
- NCT01883973
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Baylor College of Medicine