Clinical trials: Emergence From Anesthesia
Delayed Recovery From Anaesthesia
Measurement of Psychomotor Recovery After Anesthesia Using 4CRT
The aim of the investigation is to validate the SmartPhone-based 4-Reaction Choice Time Test (4CRT) as a measure for recovery of the psychomotor function in patients after general anesthesia.
- Trial name
- 4CRT (NCT02232139)
- Testing
- Midazolam
- Where
- Germany
- Volunteers
- 124 people
- Sponsor
- University Medicine Greifswald
Postoperative Residual Curarization, Residual Neuromuscular Block
Comparison Between Cisatracurium and Rocuronium in Terms of Recovery of the Muscular Strength in the Postoperative Phase After Surgery and General Anaesthesia
The purpose of this study is to determine the incidence of post-operative residual curarization in our patients and to determine if Cisatracurium and Rocuronium behave differently from each other in terms of residual curarization.
- Trial name
- NCT01651572
- Testing
- Cisatracurium, Rocuronium
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera di Padova
Postoperative Residual Curarization, Neuromuscular Blockade
Comparison of Adductor Pollicis and Abductor Digiti Minimi Muscles (Thumb Vs. Fifth Digit) As Sites for Neuromuscular Monitoring with Electromyography
This study aims to evaluate the performance of the TetraGraph on two muscle groups: the adductor pollicis and the abductor digiti minimi. Theese muscles are located on the arms.
- Trial name
- NCT06691204
- Where
- 2 sites in Hungary
- Volunteers
- 46 people
- Sponsor
- Tamas Vegh, MD
Cough
The Effect-site Concentration of Remifentanil for Preventing Cough During Emergence From Balanced Anesthesia for Nasal Surgery
After nasal surgery, emergence cough or straining will produce venous engorgement and increase bleeding from the surgical site, so the necessity for smooth extubation without severe cough during emergence provides a challenge for…
- Trial name
- NCT01291849
- Testing
- Dixon up-and-down method
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
Anesthesia
Arousal Pathways and Emergence From Sedation
Emergence from sedation involves an increase in both the level of consciousness and arousal. Some insight to the neural core of consciousness was gained in the recent past.
- Trial name
- NCT02253758
- Testing
- Propofol
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Residual Paralysis, Post-Anesthesia
Effects of Postoperative Residual Paralysis on Hospital Costs
This is a secondary analysis of a previously performed prospective, observer-blinded, observational study at Massachusetts General Hospital.
- Trial name
- NCT01718860
- Testing
- Quantitative measurement of neuromuscular transmission
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Massachusetts General Hospital
Extubation, Respiratory Depression
Effect of Percutaneous Electrical Acupoint Stimulation on the Improvement of Incidence of Adverse Respiratory Events
The goal of this study is to investigate the effect of combined acupoint electrical stimulation at Taiyuan (LU9) and Hegu (LI4) on improving the incidence of respiratory adverse events after extubation in patients during the…
- Conditions
- Extubation, Respiratory Depression, Acupuncture Points, Hypoxia
- Trial name
- NCT06772961
- Testing
- Transcutaneous electrical acupoint stimulation, Conventional care plan
- Where
- 2 sites in China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Delirium
Electroencephalographic Biomarker to Predict Postoperative Delirium
Acute post-operatory cognitive dysfunction states are one of the most important complications in older patients that underwent surgery. Among them postoperative delirium (POD) is the the most studied.
- Trial name
- NCT05992506
- Testing
- POD risk estimation using PEUMA
- Where
- 2 sites in Chile
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Chile
Emergence From Anesthesia
Electroencephalographic Trajectories During Emergence From Inhalational and Total Intravenous Anesthesia
General anesthesia emergence is a critical transition during which patients recover from an anesthetic-induced unconscious state to consciousness.
- Trial name
- NCT07806903
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Anesthesia
TEAS to Improve Outcome During Emergence From General Anesthesia After Robotic Surgery
This study is to observe whether transcutaneous electrical stimulation at specific acupoints could improve the quality of emergence in patients undergoing robotic laparoscopic gynecologic surgery.
- Trial name
- TIGER (NCT02323958)
- Testing
- acupoint stimulation, non-acupoint stimulation, electrode attached
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Air Force Military Medical University, China
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Anesthesia
Use of Tragus Pressure in Guiding Emergence From Anaesthesia
The aims of this study is to evaluate the effectiveness of tragus pressure application in predicting or facilitating recovery from general anaesthesia, and compare the reliability of tragus pressure guided recovery/ emergence…
- Trial name
- NCT04331756
- Testing
- Guiding Emergence From Anaesthesia With Tragus Pressure, Guiding Emergence From Anaesthesia Without Tragus Pressure
- Where
- Singapore
- Volunteers
- 405 people
- Sponsor
- National University Hospital, Singapore
Residual Paralysis, Post Anesthesia, Postoperative Complications
Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Despite emerging efforts to decrease residual paralysis and postoperative complications with the use of quantitative neuromuscular monitoring and reversal agents their incidences remain high.
- Conditions
- Residual Paralysis, Post Anesthesia, Postoperative Complications, Neuromuscular Blockade, Quantitative Neuromuscular Monitoring
- Trial name
- PINES (NCT05471882)
- Where
- 2 sites in Germany
- Volunteers
- 240,000 people
- Sponsor
- University Hospital Ulm
Residual Neuromuscular Blockade, Curarization, Postoperative Residual
Validation of the REPS Prediction Tool
Neuromuscular blocking agents' (NMBA) use during surgery is associated with postoperative respiratory complications and increased risk of readmission to the hospital following ambulatory surgery.
- Conditions
- Residual Neuromuscular Blockade, Curarization, Postoperative Residual, Postoperative Respiratory Complication
- Trial name
- NCT03585400
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 101,510 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Residual Paralysis, Post Anesthesia
Best Management of Muscle Relaxation- Objective Monitoring
The purpose of this study is to demonstrate that the investigators can reduce residual paralysis to a very low incidence, and that the investigators can do this while preserving a role for the older and less expensive reversal…
- Trial name
- NCT03958201
- Testing
- Protocol for Management of Muscle Relaxation With Rocuronium Using Objective Monitoring and Reversal With Neostigmine or Sugammadex
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Washington
Residual Neuromuscular Blockade
Reversal of Neuromuscular Blockade in Thoracic Surgical Patients
The majority of patients undergoing surgery receive neuromuscular blocking agents (NMBAs) in the operating room. Reversal of neuromuscular blockade at the conclusion of a general anesthetic is accomplished with cholinesterase…
- Trial name
- NCT01837498
- Testing
- Neostigmine, Sugammadex
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Endeavor Health
Hypothermia; Anesthesia, Agitation, Emergence
Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation
The main aim of our study was to investigate the relationship between perioperative hypothermia and postoperative emergence agitation.
- Conditions
- Hypothermia; Anesthesia, Agitation, Emergence, Postoperative Complications, Hypothermia Following Anesthesia
- Trial name
- NCT06543134
- Testing
- surgery, sedation scale
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Neuromuscular Blockade, Residual Neuromuscular Blockade
Neuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.
This study aims to compare two monitoring methods of neuromuscular blockade - Kine-myography and Electromyography. The main questions to answer are: are electromyography and kine-myography interchangeable is electromyography…
- Trial name
- NCT05992090
- Where
- Czechia
- Volunteers
- 129 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Neuromuscular Block, Residual
Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery
Compare the reversal effect of neostigmine and sugammadex using quantitative neuromuscular monitoring
- Trial name
- NCT03292965
- Testing
- Neostigmine, Sugammadex
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Postoperative Residual Curarisation, Postoperative Hypoxemia
Postoperative Residual Curarisation at Arrival in the Post-anesthesia Care Unit
Several studies have documented that neuromuscular block often persists in the postanesthesia care unit (PACU). Residual paralysis is associated with postoperative complications such as hypoxia, weakness, and respiratory failure.
- Conditions
- Postoperative Residual Curarisation, Postoperative Hypoxemia, Postoperative Airway Obstruction
- Trial name
- NCT01362647
- Testing
- neuromuscular transmission monitoring, Pulse oximetry measurement
- Where
- Belgium
- Volunteers
- 625 people
- Sponsor
- Onze Lieve Vrouw Hospital