Clinical trials: Emergencies, open to volunteers
Suicide, Mental Health Issue
Proximal Risk for Suicide in Adolescents
The central hypothesis is that biometric data can continuously monitor and allow for early identification/intervention of escalating suicidal symptoms.
- Trial name
- NCT06400810
- Testing
- Analog Devices Inc.
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Oregon Health and Science University
Emergency Department Discharge Communication
Examining the Effectiveness and Implementation of the Emergency Department Patient-Activated Transition to Care At Home Tool
The goal of this clinical trial is to examine the effectiveness and implementation of the Emergency Department Patient-Activated Transition to Care at Home (ED-PATCH) tool, which is used by patients to manage information during…
- Trial name
- ED-PATCH (NCT06668636)
- Testing
- ED-PATCH
- Where
- 2 sites in Canada
- Volunteers
- 12,000 people
- Sponsor
- IWK Health Centre
Dyspnea
The Impact of Telemedicine, Using the Caller's Mobile Phone Camera, on the Quality of Care Provided to Adult Patients Contacting the 15 Centre for Acute Dyspnea
Dyspnea is the subjective sensation of difficult or uncomfortable breathing. It accounts for approximately 10% of emergency department visits and 8% of calls to Emergency Medical Communication Centers.
- Trial name
- TELEDYS (NCT07726628)
- Testing
- Addition of telemedine to standard medical dispatching process
- Where
- 10 sites in France
- Volunteers
- 778 people
- Sponsor
- Poitiers University Hospital
Pediatric Emergency Care
The Effect of Using a Stress Ball and Watching Cartoons on Fear and Pain Levels During Enemas in Children Aged 6-12
Aim: The aim of this study is to investigate the effect of using a stress ball and watching cartoons during the enema procedure-performed as part of the diagnosis and treatment process-on the levels of fear and pain in children…
- Trial name
- NCT07754136
- Testing
- Cartoon watching group, Stress ball group
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Acute Heart Failure (AHF)
Early Gliflozin for Elderly Patients With Acute Decompensated Heart Failure in the Emergency Department
Background: SGLT2 inhibitors reduce CHF morbidity/mortality but are underutilized in elderly patients with acute decompensated CHF (ADCHF) admitted outside cardiology departments.
- Trial name
- GlifloFastER (NCT07392788)
- Testing
- Early initiation of dapagliflozin 10mg daily within 24h of emergency department admission, Telephone follow-up by cardiac nurse practitioner at 1 month, Standard acute decompensated heart failure care
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Macroscopic Hematuria
Causes and Management of Children Presenting With Macroscopic Hematuria in the Pediatric Emergency Department
Macroscopic hematuria. is a common symptom, leading to numerous emergency department visits in children of all ages. It can be linked to many pathologies, and its management in the emergency department is not standardized.
- Trial name
- HMUP (NCT07312461)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Trauma, Injury
Data-Driven Lay First Responder Program in Cameroon
Cameroon experiences a high burden of injury-related morbidity and mortality and currently lacks a formal pre-hospital care system.
- Trial name
- K-LFR Project (NCT07581327)
- Testing
- Lay First Responder (LFR) training
- Where
- Cameroon
- Volunteers
- 1,812 people
- Sponsor
- Sabrinah Christie
Cancer, Emergencies
Pro-active Monitoring of Vital Signs in Oncology Patients Using a Smartwatch
The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters.
- Trial name
- PROGRESS (NCT06680778)
- Testing
- Proactive Monitoring
- Where
- Netherlands
- Volunteers
- 175 people
- Sponsor
- Erasmus Medical Center
Brain Injuries, Traumatic, Brain Injuries, Acute
Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain Injury
Traumatic brain injury (TBI) and other conditions that reduce blood flow to the brain - such as cardiac arrest (CA) - are life-threatening medical emergencies.
- Conditions
- Brain Injuries, Traumatic, Brain Injuries, Acute, Hypoxia, Brain, Cardiac Arrest (CA)
- Trial name
- CHARON (NCT07782216)
- Where
- 4 sites in Hungary
- Volunteers
- 477 people
- Sponsor
- University of Pecs
Syphilis
Offering Routine and Rapid Point of Care (POC) Syphilis Testing in Pregnant Patients Presenting to the Emergency Department
The purpose of this study is to offer routine lab-based and rapid point of care (POC) syphilis diagnostic testing in the emergency department (ED) and obstetrical (OB) triage , thereby increasing screening and treatment…
- Trial name
- NCT06645106
- Testing
- Rapid Point of Care (POC) Syphilis testing
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- The University of Texas Health Science Center, Houston
Opiate-Related Disorders, Opiate Use Disorder
MedSMA℞T Mobile ED
The goal of this clinical trial is to learn if a new smartphone-based intervention can help with factors related to opioid misuse in parents and adolescent/early adult children.
- Conditions
- Opiate-Related Disorders, Opiate Use Disorder, Opioid
- Trial name
- NCT06848504
- Testing
- MedSMA℞T Mobile
- Where
- 3 sites in United States
- Volunteers
- 244 people
- Sponsor
- Olufunmilola Abraham
Suicidal Ideas, Suicidal Ideation
A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department
The purpose of this study is to test whether a lethal means safety planning intervention, TEEN LENS ED, is acceptable to teens at elevated suicide risk and their caregivers in the Emergency Department.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Suicidal Thoughts, Firearm Safety
- Trial name
- TEEN LENS ED (NCT07916792)
- Testing
- TEEN LENS, Usual Care
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Pulmonary Aspiration, Emergency Surgery
Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Pulmonary aspiration of gastric contents is a serious patient safety problem accounting for 50% of anesthesia-related mortality.
- Trial name
- NCT06303492
- Testing
- GUS
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Shortness of Breath
Effectiveness of a Mastery Learning Education Program for Parents of Children Using Inhaler Therapy in an Emergency Unit
Respiratory diseases account for a significant proportion of pediatric emergency department admissions, and effective management of respiratory conditions in children is crucial.
- Trial name
- NCT07452731
- Testing
- Parent Education Program, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Emine ŞAHİN
Abdominal Pain (AP), Acute Abdomen
Emergency Medicine Evaluation for Acute Abdominal Pain - a Pragmatic Randomized Trial
The goal of this clinical trial is to learn whether initial assessment by a physician specializing in emergency medicine can improve the care of adults who come to the emergency department with acute abdominal pain or another…
- Conditions
- Abdominal Pain (AP), Acute Abdomen, Acute Abdominal Pain, Abdomen, Acute
- Trial name
- EMERGE-Abdomen (NCT07815795)
- Testing
- Emergency Medicine Initial Assessment, Standard Surgical Assessment
- Where
- Norway
- Volunteers
- 440 people
- Sponsor
- Haukeland University Hospital
Trauma and Emergency Care, Shock,Hemorrhagic
Delayed Fluids in Hemorrhagic Shock Due to Severe Injuries.
This study will provide information on the quality of care in hemorrhagic shock of severe injuries in a limited resource facility of Latin America, the strategies of fluid resuscitation, and outcomes.
- Conditions
- Trauma and Emergency Care, Shock,Hemorrhagic, Intravenous Fluid Therapy
- Trial name
- PERMIT-LATAM (NCT07530653)
- Testing
- Crystalloid below 1000 mL., IV fluids more than 1,000 mL
- Where
- Colombia
- Volunteers
- 716 people
- Sponsor
- Hospital Departamental de Villavicencio
Sepsis in ED Patients
REDS SCORE VERSUS qSOFA SCORE to Predict Mortality in Patients With Suspected Sepsis
Our goal in this work is to compare the predictive accuracy of the REDS score versus qSOFA in identifying in-hospital mortality among ED patients with suspected sepsis and improving outcomes in ED patients.
- Trial name
- NCT07271329
- Testing
- Sphygmomanometer
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Small Bowel Obstruction
Contribution of Point of Care Ultrasound by the Emergency Physician to Rule Out the Small Bowel Obstruction: a Diagnostic, Multicenter Study
Small Bowel Obstruction (SBO) is a frequent pathology in the emergency department (ED). Diagnosis is currently based on abdominal CT scan (CT).
- Trial name
- OCCLUS-POCUS (NCT06803628)
- Testing
- Point of care ultrasound
- Where
- 18 sites in France
- Volunteers
- 667 people
- Sponsor
- Nantes University Hospital
Supraventricular Tachycardia (SVT)
Adenosine vs Diltiazem for Treatment of SVT in the ED
This is a small, pilot study with a primary goal of assessing patient perceptions of two medication treatments for supraventricular tachycardia in adult patients treated in the Emergency Department.
- Trial name
- COMFORT-ED (NCT06993038)
- Testing
- adenosine, diltiazem
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Anne E. Zepeski
Screening Compliance, Lung Cancer (Diagnosis)
Increasing Lung Cancer Screening Uptake Among Emergency Department Patients
The objective of the proposed clinical trial is to determine if we can increase LCS among ED patients using a combination of facilitated referral to an LCS program plus text message reminders to get screened.
- Conditions
- Screening Compliance, Lung Cancer (Diagnosis), Lung Cancer Diagnosis, Lung Cancer
- Trial name
- NCT07287085
- Testing
- Facilitated referral and text messaging, Basic Referral (enhanced control arm)
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Rochester