Clinical trials: Emergencies
Patients Emergency On-site Care by Mobile Emergency Unit
Impact of a Teleconsultation Performed During Ambulance's Displacement
The establishment of pre-hospital care protocols has shown benefits in the prognosis of numerous acute situations, such as myocardial infarction and stroke, but travel time to the hospital is still a key factor in clinical…
- Trial name
- NCT05274724
- Testing
- No teleconsultation during the ambulance journey, Teleconsultation during the ambulance journey
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Israelita Albert Einstein
Penicillin Allergy
Oral Penicillin Challenge and Allergy De-labeling in Children
The primary purpose of this study is to investigate the portion of penicillin allergy labels that are not true allergies using oral amoxicillin challenges among pediatric patients.
- Trial name
- NCT05563610
- Testing
- Amoxicillin 500mg
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Phoenix Children's Hospital
Intravenous Infusions
Single-operator Ultrasound-guided IV Placement by Emergency Nurses
The placement of peripheral intravenous lines (IVs) is central to the treatment of patients in the emergency department (ED). The procedure is used for phlebotomy and administration of a variety of therapeutic medications and…
- Trial name
- NCT01439113
- Testing
- Ultrasound guided IV placement
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tufts Medical Center
Seizures
Pediatric Dose Optimization for Seizures in Emergency Medical Services
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances.
- Trial name
- PediDOSE (NCT05121324)
- Testing
- Standardized seizure protocol, Conventional seizure protocol
- Where
- 20 sites in United States
- Volunteers
- 6,700 people
- Sponsor
- Stanford University
Emergencies, Diagnoses Disease
Digitalized Differential Diagnosis Broadening in Emergency Rooms
10 to 35% of patients admitted to an emergency department receive an incorrect diagnosis. Not surprisingly, given the wide variety of health conditions encountered in emergency medicine, physicians often do not consider…
- Trial name
- DDX-BRO (NCT05346523)
- Testing
- Isabel Pro - The DDx generator (CDDS)
- Where
- 4 sites in Switzerland
- Volunteers
- 1,218 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain, Anxiety
Lumbar Puncture in Emergency Under Nitrous OXide
Lumbar puncture (LP) is a frequent exam that can cause pain and anxiety. In a scheduled setting, it has been shown that nitrous oxide use during the procedure was able to reduce both pain and anxiety.
- Trial name
- LENOX (NCT03941990)
- Testing
- Fixed 50:50 mixture of nitrous oxide and oxygen
- Where
- France
- Volunteers
- 88 people
- Sponsor
- University Hospital, Clermont-Ferrand
Vascular Access, Emergencies
POCUS for Difficult Peripheral Access in the Emergency Department - a RCT
Peripheral intravenous line insertion is the most commonly performed invasive procedure in the emergency department (ED). The research hypothesis is that a biplane sonographic approach (i.e., an out-of-plane and in-plane view)…
- Trial name
- NCT05119673
- Testing
- bi-plane sonographic view to difficult peripheral vascular access using Butterfly iQ+®
- Where
- Italy
- Volunteers
- 442 people
- Sponsor
- University of Turin, Italy
Emergency Service, Hospital
Informing Low-acuity Emergency Department Patients of Non-emergent Resources
The goal of this campaign is to reduce unnecessary visits to a Geisinger emergency department (ED)/encourage patients with high acuity visits to follow up with an appropriate Geisinger provider.
- Trial name
- NCT06350266
- Testing
- Information about healthcare resources
- Where
- United States
- Volunteers
- 6,242 people
- Sponsor
- Geisinger Clinic
Stroke Syndrome, Stroke Hemorrhagic
Assessing Accuracy of Clinical Diagnosis and Lesion Location in Acute Neurological Deficits - How Good Are Neurologists?
The emergency setting for acute neurological conditions, such as stroke, is peculiar due to time pressure and limited resources for further diagnostics.
- Conditions
- Stroke Syndrome, Stroke Hemorrhagic, Stroke, Acute, Strokes Thrombotic
- Trial name
- HOGAN (NCT03009656)
- Testing
- No study specific interventions
- Where
- Switzerland
- Volunteers
- 800 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Community-acquired Pneumonia
Accuracy of Lung Injury Biomarkers in the Initial Investigation of Patients With Suspected Pneumonia
The aim of this study is to investigate the diagnostic and prognostic value of surfactant protein D, Krebs von den Lungen (KL-6), and Chitinase-3-like protein 1 (YKL-40) in the initial investigation of patients hospitalized with…
- Trial name
- NCT04686331
- Testing
- Biomarkers for pneumonia
- Where
- Denmark
- Volunteers
- 411 people
- Sponsor
- University of Southern Denmark
Troponin T, Hemolysis
Effect of in Vitro Haemolysis on Serum High Sensitivity Troponin T Measurements From Patients in Accident & Emergency
This study will be investigating how a common blood test for identifying heart damage (Troponin T) is affected by red blood cell damage in the blood sample (Haemolysis).
- Trial name
- NCT03439605
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Violence
University of Michigan Youth Violence Prevention Emergency Department Brief Intervention (Project Sync)
The purpose of this study is to determine whether a brief motivational interviewing intervention given during emergency department care to 14-20 year olds seeking treatment, could reduce youth violence.
- Trial name
- NCT02586766
- Testing
- Project Sync
- Volunteers
- 409 people
- Sponsor
- University of Michigan
Psychiatric Patients, Serious Medical Illness
Missed Serious Medical Illness in Psychiatric Patients Seen in an Academic Emergency Department
The purpose of this study is to determine the prevalence, etiology, and timing of missed Serious Medical Illness (SMI) in patients referred to adult psychiatry by emergency physicians, as well as to determine admission rates for…
- Trial name
- NCT02589951
- Testing
- admission to non-psychiatric service
- Where
- Canada
- Volunteers
- 2,200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hiv, Hepatitis C
Development and Pilot Testing of a PHCI for Emergency Department Patients Who Decline Rapid HIV/ HCV Screening
The Centers for Disease Control and Prevention (CDC) recommends that emergency departments (EDs) and other health care facilities conduct HIV and HCV screening to identify and link to care those with undiagnosed infections.
- Trial name
- NCT04137094
- Testing
- Persuasive Health Communication Intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Emergencies, Flu
Burden of Influenza at Emergency Department Level : BIED
Seasonal influenza surveillance in France relies on several sources to detect the onset of the epidemic early, as well as to estimate the severity of epidemics and their impact on the health system.
- Trial name
- BIED (NCT04153331)
- Testing
- Nasal swab
- Where
- France
- Volunteers
- 2,487 people
- Sponsor
- Hospices Civils de Lyon
Emergency Medical Services, Triage
Reliability of the Swiss Emergency Triage Scale (SETS®) Used by Emergency Medical Service (EMS) Providers
The Swiss Emergency Triage Scale (SETS) in used for triage in emergency departments in Switzerland, France and Belgium. No validated triage scale is actually used by Emergency Medical Service (EMS) providers.
- Trial name
- NCT02559531
- Testing
- Mobile triage system
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
HIV Infections, Contraception
A Study of the Drug Interactions Between a Hormonal Emergency Contraception and an HIV Medication
The purpose of this study is to determine if blood levels of the hormonal emergency contraceptive agent, Plan B, are altered by concomitant use with the HIV medication, efavirenz.
- Conditions
- HIV Infections, Contraception, Pharmacokinetics
- Trial name
- NCT00482963
- Testing
- levonorgestrel, efavirenz
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Myocardial Infarction
Feasibility and Security of a Rapid Rule-out and rule-in Troponin Protocol in the Management of NSTEMI in an Emergency Departement
Management of NSTEMI in emergency departements represent 10% of the global activity. Since the the last European Society of Cardiology recommendation the use of an 1 hour rule-in and rule-out protocol is recommended combined with…
- Trial name
- ICTUS (NCT03668587)
- Testing
- Troponin Protocol
- Where
- France
- Volunteers
- 1,099 people
- Sponsor
- Nantes University Hospital
Fever, Sepsis
AION BIOSYSTEMS, INC. Tempshield for Continuous Tempreature Monitoring
The purpose of this research study is to evaluate the effectiveness of the AION BIOSYTEMS, INC. tempshield ("Shield") temperature monitoring device and platform in detecting body temperature for children 2-4 years old.
- Trial name
- NCT07145541
- Testing
- Aion Tempshield Device
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- AION Biosystems
Community-acquired Pneumonia, Dyspnea
Chest CT-scan for the Diagnosis of Community-acquired Pneumonia
Primary objective : to estimate impact of CT-scan on diagnostic for emergency department (ED) patients with suspected Community-acquired Pneumonia (CAP).
- Trial name
- PACSCAN (NCT01574066)
- Testing
- Chest CT-scan
- Where
- 4 sites in France
- Volunteers
- 339 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris