Clinical trials: Emergency Airway Management
Acute Respiratory Failure
Pragmatic Trial Examining Oxygenation Prior to Intubation
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- PREOXI (NCT05267652)
- Testing
- Preoxygenation with Non-Invasive Positive Pressure Ventilation, Facemask Oxygen
- Where
- 16 sites in United States
- Volunteers
- 1,301 people
- Sponsor
- Vanderbilt University Medical Center
One-year Outcome After Prehospital Intubation
One-year Outcome After Prehospital Intubation
The primary aim of this study was to describe the long-term outcome of critically ill or severely injured patients not in cardiac arrest treated by an EMS physician.
- Trial name
- NCT02307123
- Testing
- Intubation
- Volunteers
- 483 people
- Sponsor
- Tampere University Hospital
Acute Respiratory Failure
Bougie Use in Emergency Airway Management
This prospective, open-label trial randomizes adult patients intubated in the ED with a Macintosh blade to use or not use a bougie for the first intubation attempt. The primary outcome is first pass success.
- Trial name
- BEAM (NCT02902146)
- Testing
- Bougie, Endotracheal tube
- Where
- United States
- Volunteers
- 757 people
- Sponsor
- Hennepin Healthcare Research Institute
Acute Respiratory Failure
DirEct Versus VIdeo LaryngosCopE Trial
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- DEVICE (NCT05239195)
- Testing
- Video Laryngoscope, Direct Laryngoscope
- Where
- 12 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Vanderbilt University Medical Center
Oral Intubation
GlideScope Versus Direct Laryngoscope for Emergency Intubation
The purpose of this study is to assess if the GlideScope video laryngoscope is superior to the Macintosh direct laryngoscope for definitive airway management in acutely-injured patients.
- Trial name
- NCT01235065
- Testing
- type of laryngoscope
- Where
- United States
- Volunteers
- 623 people
- Sponsor
- University of Maryland, Baltimore
Acute Respiratory Failure
Randomized Trial of Sedative Choice for Intubation
Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death.
- Trial name
- RSI (NCT05277896)
- Testing
- Ketamine, Etomidate
- Where
- 6 sites in United States
- Volunteers
- 2,367 people
- Sponsor
- Vanderbilt University Medical Center
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute