Clinical trials: Emergency Contraception
Pregnancy Prevention
Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days
This clinical trial determines if an oral medication taken within 2 days of anticipated ovulation will delay ovulation by 7 days.
- Trial name
- OVULATION (NCT05695352)
- Testing
- Levonorgestrel 1.5mg, Meloxicam 15 mg
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Contraception
Study Comparing Emergency Contraception Effectiveness in Women Who Weight ≥ 80 kg
The proposed research study is a Phase IIb, multi-center, single-blind, randomized study of UPA 30 mg, LNG 1.5 mg and LNG 3.0 mg to evaluate EC effectiveness in women with weight ≥ 80 kg who present within 72 hours of unprotected…
- Trial name
- NCT03537768
- Testing
- Ulipristal Acetate, Levonorgestrel
- Where
- 18 sites in United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Kimberly Myer
Obesity
Effects of Obesity on Pharmacokinetics of the Levonorgestrel Emergency Contraceptive Pill
The purpose of this study is to determine the effects of obesity on the pharmacokinetics of the levonorgestrel (LNG) only emergency contraceptive (EC) regimen and on markers of ovulation Primary hypothesis: 1) Obese users of…
- Trial name
- NCT02104609
- Testing
- Levonorgestrel 1.5mg by mouth once
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Emergency Contraception, Healthy, Reproductive Age Women
Application for the Etonogestrel/Ethinyl Estradiol Ring
This study is enrolling healthy women ages 18-39yo who are not pregnant or breastfeeding, and are not using hormonal birth control.
- Trial name
- AFTER (NCT03120728)
- Testing
- Etonogestrel/ethinyl estradiol contraceptive vaginal ring
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Emergency Contraception, Contraception
Depot Medroxyprogesterone Acetate as Emergency Contraception
Background: The prevalence of repeat unprotected intercourse after EC use in the same cycle demonstrate the need for more self-bridging emergency contraceptive options.
- Trial name
- NCT03395756
- Testing
- Depot-Medroxyprogestereone Acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Emergency Contraception
Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception
This is a randomised controlled trial aimed at comparing the efficacy of levonorgestrel (LNG) co-administered with piroxicam or placebo for oral emergency contraception (EC).
- Trial name
- NCT03614494
- Testing
- Piroxicam 40 mg, Levonorgestrel 1.5mg
- Where
- 2 sites in Hong Kong
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Dr. Hang Wun Raymond Li
Contraception
Ovarian Function With ENG Implant and UPA Use
Same day initiation of the etonogestrel (ENG) implant and oral ulipristal acetate (UPA) would overcome contraceptive access barriers to people capable of pregnancy with recent unprotected intercourse to ongoing contraception.
- Trial name
- NCT04291001
- Testing
- ENG implant, oral ulipristal acetate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Emergency Contraception, Abortion, Induced
Medical Abortion for Emergency Contraception Failure
The purpose of this study is to compare the efficacy, safety and acceptability of pre-treatment with mifepristone and misoprostol compared to misoprostol alone in the medical termination of pregnancy by mifepristone EC failure.
- Trial name
- NCT00677755
- Testing
- mifepristone combined misoprostol, misoprostol alone protocol
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Taizhou Hospital
Contraception
RAPID EC - Rct Assessing Pregnancy With Intrauterine Devices for EC
This study is a randomized trial of two IUDs for emergency contraception: the copper IUD, the most effective method of emergency contraception vs.
- Trial name
- NCT02175030
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- 6 sites in United States
- Volunteers
- 711 people
- Sponsor
- University of Utah
HIV Infections, Tuberculosis
Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy
The purpose of this pharmacokinetic (PK) study was to evaluate if a double dose (3 mg) of levonorgestrel (LNG) overcomes known drug-drug interactions (DDIs) with efavirenz (EFV)-based antiretroviral therapy (ART) or rifampicin…
- Trial name
- NCT03819114
- Testing
- Levonorgestrel (LNG)
- Where
- 18 sites in United States, Botswana and 5 more
- Volunteers
- 122 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Pregnancy Prevention
Phase II Study of Ovulation in Obese Women
The goal of this clinical trial is to compare the delay in ovulation between placebo to levonorgestrel plus meloxicam in obese women with normal menses. The main questions it aims to answer are: 1.
- Trial name
- NCT06306131
- Testing
- Levonorgestrel 1.5 milligram, Meloxicam 15 milligram, calcium carbonate 750 milligram
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- InnovaGyn, Inc.
Emergency Contraception
Study of the Copper IUD or Oral Levonorgestrel and the Levonorgestrel IUD for Women Seeking Emergency Contraception
The purpose of this study is to see how often women who come to a family planning clinic for emergency contraception, the morning after pill, are willing to use either the copper IUD or the levonorgestrel IUD.
- Trial name
- COLIEC (NCT01963962)
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Utah
Contraception
Targeted Video Messaging About Emergency Contraception
This research study will assess the real-world effectiveness of Facebook advertising as a strategy to reach women of reproductive age who are at risk of unintended pregnancy with a brief educational intervention about emergency…
- Trial name
- NCT03774368
- Testing
- Emergency contraception website, Emergency contraception video
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Pregnancy
Randomized Trial of Advanced Provision Emergency Contraception Among Women With Gonorrhea or Chlamydia
The purpose of this trial is to determine whether providing non-contracepting women with gonorrhea or chlamydial infection with advanced provision emergency contraception (APEC) and condoms decreases their risk of becoming…
- Trial name
- NCT00520455
- Testing
- levonorgestrel 0.75mg taken twice 12 hours apart (Plan B) and condoms
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- University of Washington
Pregnancy, Unplanned, Pregnancy; Accident
Levonorgestrel Intrauterine System For Emergency Contraception
The purpose of this research study is to test the levonorgestrel intrauterine system as a method for emergency contraception. Emergency contraception refers to pregnancy prevention after an act of intercourse.
- Trial name
- LIFE (NCT01539720)
- Testing
- Ulipristal acetate, levonorgestrel IUS
- Where
- 3 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of the St. Louis Region and Southwest Missouri
Preconception Care
Computer-assisted Preventive Health Education for Women of Reproductive Age in Urgent Care Settings
The purpose of this study is to determine whether "video doctor" programs can effectively deliver preventive health messages to women of reproductive age while they wait to be seen in urgent care settings.
- Trial name
- NCT00177515
- Testing
- "video doctor," computer module
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Emergency Contraception
Awareness & Use of Emergency Contraception
General objective: To decrease the percentage of unwanted and/or unplanned pregnancies and their consequences on women's reproductive health. Specific objectives: 1.
- Trial name
- NCT04172584
- Testing
- correct use of the contraceptions
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post Partum
Advance Supply of Emergency Contraception Compared to Routine Postpartum Care in Teens
This is a pilot randomized controlled trial to assess the effects of advanced supply of emergency contraception versus routine care in a teen postpartum population.
- Trial name
- NCT00433004
- Testing
- Plan B (Levonorgestrel)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Contraception
Ulipristal Emergency Contraception Used Before or After Ovulation
This was a prospective, open-label, single-drug, uncontrolled, observational clinical study. Women attending the Family Planning Association of Hong Kong (FPAHK) for emergency contraception within 120 hours of UPSI were…
- Trial name
- NCT02517463
- Testing
- Ulipristal acetate
- Volunteers
- 700 people
- Sponsor
- The University of Hong Kong
Contraceptive Usage
Disparities in Emergency Contraceptive Metabolism Dictate Efficacy
The purpose of this study is to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not.
- Trial name
- NCT05674513
- Testing
- Ulipristal acetate
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University