Clinical trials: Emergency Departments
Clinical Decision Support, Clinical Practice Guidelines
Professional Development in Emergency Medical Services
The ProDEms-trial focuses on nurses and ambulance drivers working in prehospital care, taking care on the one hand of patients suffering from time-sensitive critical conditions like STEMI, acute stroke or severe traumatic brain…
- Conditions
- Clinical Decision Support, Clinical Practice Guidelines, Emergency Medical Services
- Trial name
- ProDEms (NCT02365792)
- Testing
- Clinical Decision Support Tool for Prehospital Care
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Migraine Headache
Auricular Acupuncture vs SOC in Migraine HA
Patients with migraine headache will be offered the opportunity to participate in this randomized study evaluating auricular acupuncture versus standard treatment for migraine headaches for patients in the pediatric emergency…
- Trial name
- MigAcu (NCT02681211)
- Testing
- Auricular Acupuncture, Ketorolac 0.5mg/kg, max 30mg, Metoclopramide 0.1 mg/kg, max 10mg
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Louisville
Vomiting, Nausea
Inhaled Isopropyl Alcohol for Treatment of Nausea
To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.
- Conditions
- Vomiting, Nausea, Children, Only
- Trial name
- NCT05418244
- Testing
- Inhaled Isopropyl Alcohol, Oral Ondansetron
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Severe Asthma
Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA)
Adults with severe asthma may have sudden worsening shortness of breath that results in their going to Emergency Department for urgent care.
- Trial name
- TERAA (NCT06705764)
- Testing
- Tezepelumab
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Croup
Impact of Cold Air Exposure on Croup Symptoms
The goal of the present randomised controlled clinical trial is to compare the efficacy of a 30-minute exposition to cold, atmospheric, outdoor air on the severity of croup symptoms with exposition to indoor room air in children…
- Trial name
- NCT05668364
- Testing
- Outdoor cold air exposure
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Rib Fracture
Comparison of Gray-scale Inverted Rib Series With Conventional Ones in Rib Fracture Detection by Emergency Physicians and Medical Students
There were many studies which examined the availability of inverted gray-scale chest X-ray for increasing the detection of lung nodules.
- Trial name
- NCT02028611
- Volunteers
- 55 people
- Sponsor
- Hanyang University
Analgesia
Efficacy of Paracetamol in Addition to Morphine to Improve Analgesia in the Emergency Department
The purpose of this study is to test the additional effect of paracetamol in combination with morphine for analgesia, respectively to test/confirm an opioid sparing effect due to the additional use of Paracetamol, as well as the…
- Trial name
- ParaMoED (NCT03843281)
- Testing
- Paracetamol, Morphine
- Where
- Switzerland
- Volunteers
- 222 people
- Sponsor
- Bruno Minotti
Trauma
Non-invasive Tool for Measuring Hemoglobin in Severe Trauma Patients in the ED
The development of miniaturized analytical technologies has facilitated the gradual decentralization of part of the laboratory examinations to the patient.
- Trial name
- HbOxymeter (NCT04988711)
- Testing
- Hb Oxymeter
- Where
- 2 sites in Tunisia
- Volunteers
- 100 people
- Sponsor
- Hôpital Universitaire Sahloul
Pneumonia, Bacterial
Urease Breath Test for Rapid Characterization of Pneumonia
This is a Phase 1, open label, evaluation of a 13C-urea breath test for the detection of urease-producing bacteria in patient with pneumonia in the emergency department.
- Trial name
- NCT03100760
- Testing
- 13C-urea breath test
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of New Mexico
Mental Health Disorder, Mental Disorder
Impact of Psychological Therapies on Emergency Medical Patients
Prevalence of anxiety and depression in the general population is known, but is under researched in the acute hospital setting and there is little evidence on the prevalence of anxiety and depression within the emergency medical…
- Conditions
- Mental Health Disorder, Mental Disorder, Mental Health Wellness 1
- Trial name
- NCT05303870
- Testing
- Improving access to psychological therapies (IAPT)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
Laceration of Skin, Anesthesia, Local
Double-dorsal Versus Single-volar Digital Block
The aim of this study is to compare the traditional dorsal double injection digital block with the palmar single injection technique in the suturing of acute traumatic hand finger lacerations in terms of injection pain score…
- Conditions
- Laceration of Skin, Anesthesia, Local, Pain, Nerve Block
- Trial name
- NCT06274073
- Testing
- Dorsal digital block, Palmar digital block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Ischemic Stroke
Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients With Acute Ischemic Stroke
According to the Bigdata Observatory platform for Stroke of China (BOSC), the proportion of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis or endovascular treatment in China is 5.64% and 1.45%…
- Trial name
- i-Path (NCT06613074)
- Testing
- Ali Pay intelligent navigation applet
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Frailty in Aging, Emergency Department Visit
Patient Experience of CFS-assessment in the ED
An increasingly common subject of interest among emergency care research is frailty, which is commonly described as a decline in several inter-related physiological systems, in addition to an increased vulnerability to stressors.
- Conditions
- Frailty in Aging, Emergency Department Visit, Patient Experience, Qualitative Research
- Trial name
- NCT06621290
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- University Hospital, Linkoeping
ERAS, Cesarean Section Pain
Enhanced Recovery After Emergency Cesarean Section: A Comparative Study Assessing Postoperative Recovery and Outcomes
Cesarean section (CS) remains one of the most common major surgical procedures worldwide, with emergency CS accounting for approximately 30% of cases.
- Trial name
- ERAS (NCT07242924)
- Volunteers
- 100 people
- Sponsor
- Assiut University
Healthy
Impact of Stress and Sleep Management on Emergency Professionals
The investigators hypothesize that a recovery management program could have an impact on emergency nurses and physicians by improving their sleep and reducing their psychological and physiological responses when dealing with…
- Trial name
- REST (NCT05251246)
- Testing
- recovery management program
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pregnancy During Breastfeeding, Lactational Amenorrhea Method
Emergency Contraception as a Back up of Lactational Amenorrhea Method(LAM)
Prolonged breast-feeding is an encouraged tradition in Egypt. Breastfeeding is associated with variable degrees of amenorrhea and infertility but there is a risk of resumption of fertility and therefore, of conception during…
- Trial name
- ECLAM (NCT01111929)
- Testing
- Counseling for LAM+ LNG-EC
- Volunteers
- 1,174 people
- Sponsor
- Assiut University
Shock
The Use of the USCOM Device in Addition to Cardiac Ultrasound in Patients Undergoing Treatment for Undifferentiated Shock
Currently, bedside ultrasound (US) is performed routinely in emergency department (ED) patients with undifferentiated shock to help guide resuscitation.
- Trial name
- NCT01981629
- Testing
- USCOM
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Hennepin Healthcare Research Institute
Health Care Reform, Health Policy
Impact of Medicaid Expansion on Healthcare Utilization
The Patient Protection and Affordable Care Act (PPACA) came into law in 2010. Originally, according to the Act, a state would lose its federal Medicaid funding if it did not expand its Medicaid eligibility to include all persons…
- Trial name
- NCT03197831
- Volunteers
- 177 people
- Sponsor
- University of Arkansas
Colorectal Cancer
Function and Quality of Life After Emergency vs Planned Creation of a Stoma
The aim is to compare functional outcome and or quality of life in patients with a stoma that was constructed as an emergency procedure with patients where a stoma was created as a planned procedure.
- Trial name
- StomaFUNQ (NCT05102981)
- Testing
- emergency procedure
- Where
- Sweden
- Volunteers
- 700 people
- Sponsor
- Eva Haglind, MD, PhD, professor
Pain, Acute Pain
Optimal Management of Pain in Hospitalized Patients - Opioid Tolerant Populations.
Pain is a symptom that drives hospital admissions, and pain management is required by most patients during their hospital stay. Further, the use of medications such as opioids can lead to upward-spiraling doses, especially among…
- Conditions
- Pain, Acute Pain, Postoperative Pain
- Trial name
- NCT02470728
- Testing
- New Clinical Pathway
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Duke University
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