Clinical trials: Emergency Departments
Sickle Cell Anemia Crisis
Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?
The purpose of this study is to determine whether IV acetaminophen can decrease the need for subsequent opioid administration in the acute management of sickle cell crisis pain in the pediatric emergency room.
- Trial name
- NCT03541980
- Testing
- Acetaminophen, Normal saline
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Newark Beth Israel Medical Center
Housing Problems, Drug Use
ED-Home Pilot Study
This is a single-arm pilot study to test the feasibility of homelessness prevention and substance use interventions to be delivered to at-risk patients in the Bellevue Hospital emergency department (ED).
- Conditions
- Housing Problems, Drug Use, Alcohol; Use, Problem
- Trial name
- NCT03864341
- Testing
- Referral to homelessness prevention services, Substance use services, Follow-up
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Contraception
Ulipristal Emergency Contraception Used Before or After Ovulation
This was a prospective, open-label, single-drug, uncontrolled, observational clinical study. Women attending the Family Planning Association of Hong Kong (FPAHK) for emergency contraception within 120 hours of UPSI were…
- Trial name
- NCT02517463
- Testing
- Ulipristal acetate
- Volunteers
- 700 people
- Sponsor
- The University of Hong Kong
Myocardial Ischemia
Increased CRP Concentrations in Patients Admitted to the Emergency Department With Troponin Elevation Aids to Rule Out Coronary Ischemia
The investigators hypothesized that the CRP/troponin ratio measured in patients presenting to the ED with elevated troponin levels could differentiate between patients with cardiac ischemia and those who present due to a systemic…
- Trial name
- NCT04522583
- Testing
- Diagnosis of Myocardial Ischemia
- Where
- Israel
- Volunteers
- 15,000 people
- Sponsor
- Hillel Yaffe Medical Center
Influenza
Influenza Vaccination in the Emergency Department
Randomized controlled trial of influenza vaccination versus referral for vaccination in the Emergency department. Is the Emergency Department an effective venue for vaccination for influenza? Does vaccination for influenza in the…
- Trial name
- NCT00822627
- Testing
- Influenza Vaccination, Education and referral
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Out-of-hospital Cardiac Arrest
CPR Quality Between Flexible Stretcher and Standard Stretcher in OHCA
This study aims to compare the quality of emergency medical services cardiopulmonary resuscitation between flexible stretcher and standard stretcher during ambulance transport to hospital among out-of-hospital cardiac arrest…
- Trial name
- ASIA-CPR (NCT02527694)
- Testing
- Flexible EMS stretcher cart, mechanical CPR
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Seoul National University Hospital
Acute Low Back Pain, Musculoskeletal Pain
Physiotherapy in Emergency Department for Acute Lumbar Spasm
This retrospective observational study aims to evaluate the effectiveness of physiotherapy interventions-such as manual therapy, electrotherapy (TENS), and individualized exercise programs-in managing acute lumbar spasm in…
- Conditions
- Acute Low Back Pain, Musculoskeletal Pain, Emergency Care
- Trial name
- PT-ED (NCT06987656)
- Testing
- Standard Pharmacologic Treatment, Physiotherapy Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Duzce University
Placenta Previa, Placenta Accreta Spectrum
Planned Delivery at 37 Versus 36 Weeks in Pregnancies With Placenta Previaand Accreta
Current clinical practice guidelines recommend planned cesarean delivery(CD) at 34-37 weeks of gestation in pregnant women with placenta previa and accreta.
- Conditions
- Placenta Previa, Placenta Accreta Spectrum, Antepartum Bleeding, Emergency Cesarean Section
- Trial name
- NCT07025954
- Testing
- Cesarean delivery
- Where
- 6 sites in China
- Volunteers
- 600 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Emergency Medical Service, Assessment
Does Assessment of Ambulance Medical Service Leads to Reduced Number of Transports to the Emergency Room?
There is a need to reduce the number of ambulance transports to the Emergency Room to the patients who are not in need of urgent medical care.
- Conditions
- Emergency Medical Service, Assessment, Registered Nurse
- Trial name
- NCT03466905
- Testing
- Ambulant assessment
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Dalarna County Council, Sweden
Opioid-related Disorders, Opioid Addiction
ER/LA Opioid Surveillance for Emergency Department Visits and Hospitalizations for Overdose and Poisoning
Study to evaluate the impact of the ER/LA opioid REMS program on the incidence of Emergency Department visits and hospitalizations for overdose/poisoning and death among patients prescribed ER/LA opioid analgesics.
- Conditions
- Opioid-related Disorders, Opioid Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02866266
- Testing
- Retrospective database review
- Volunteers
- 183,452 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)
Upper Respiratory Tract Infections, Nasal Suction
Effectiveness of the NoseFrida Compared With Bulb Suction at Relieving Objective Signs of Nasal Obstruction and Reducing Return Visits in Pediatric Patients Presenting to the Emergency Department
The mainstay of treatment in viral upper and lower respiratory tract disease is airway clearance. Viral respiratory tract infections account for a substantial amount of emergency department (ED) visits, financial and stress…
- Conditions
- Upper Respiratory Tract Infections, Nasal Suction, Return Emergency Department Visits
- Trial name
- NCT03666429
- Testing
- Bulb suction, NoseFrida
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Acute Ischemic Stroke
Prehospital Response and Emergency Stroke Transport Optimisation
This study aims to develop and evaluate an innovative prehospital emergency transport system for patients with acute ischemic stroke to reduce delays in reperfusion treatment.
- Trial name
- PRESTO (NCT07892053)
- Testing
- Innovative pre-hospital emergency transport system for acute ischemic stroke
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Musculoskeletal Disorders, Emergency Care
Effect and Cost of a Physiotherapy-led Care Model in Emergency Departments for Patients With Minor Musculoskeletal Injuries
Both in Denmark and internationally, emergency departments have been overwhelmed for several years by a growing number of patients, combined with a shortage of doctors and nurses.
- Conditions
- Musculoskeletal Disorders, Emergency Care, Physiotherapy
- Trial name
- NCT07137754
- Testing
- Advanced practice physiotherapy, Usual Care
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Aarhus University Hospital
Emergency Care, Obstetric
Emergency Obstetric Care Protocol
This study aims to investigate the effect of applying emergency obstetric care protocol on maternity nurses' practices.
- Trial name
- NCT07248605
- Testing
- educational booklet
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Triage, Emergency Medical Services
Clinical Predictors of Capillary Refill Time and Their Association With Triage Categories
This observational study aims to determine the correlation between capillary refill time (CRT) and vital parameters in patients presenting to the emergency department.
- Conditions
- Triage, Emergency Medical Services, Vital Signs Monitoring, Hypoperfusion
- Trial name
- CRT_TriageER (NCT07054151)
- Testing
- No clinical intervention (observational study only)
- Where
- Turkey (Türkiye)
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Bacterial Infections, Gram-Positive Bacterial Infections
What is the Prevalence of Methicillin-Resistant Staphylococcus Aureus in Skin and Soft Tissue Infections Presenting to the Emergency Departments of a Canadian Academic Health Care Center?
Staphylococcus aureus is the most common bacteria responsible for skin, bone, and muscle infections. Recent studies from the United States have suggested that a type of this bacterium called methicillin resistant S.
- Conditions
- Bacterial Infections, Gram-Positive Bacterial Infections, Staphylococcal Infections
- Trial name
- CA-MRSA (NCT00736554)
- Where
- Canada
- Volunteers
- 152 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Severe Acute Pain
A Non-randomised, Non-inferiority Comparative Study of Oral Actiskenan (Morphine Sulfate) Versus Intranasal Sufentanil in the Early Management of Severe Acute Pain in Emergency Departments.
The main objective of this study is to evaluate whether the analgesic protocol combining oral Actiskenan is non-inferior to the protocol combining intranasal Sufentanil for treating severe pain in patients admitted to the…
- Trial name
- SA-URGE (NCT07344350)
- Testing
- Intranasal Sufentanil, Oral Actiskenan
- Where
- 2 sites in France
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Pain, Pain, Acute
Opioid Use and Predicting Factors at the Emergency Department
Background: Increasing opioid misuse is a worldwide problem. About 10% of opioid misusers are primarily exposed to opioids at the Emergency Department (ED).
- Trial name
- VRxOPUS-1 (NCT06072950)
- Testing
- Usual care
- Where
- Netherlands
- Volunteers
- 149 people
- Sponsor
- Radboud University Medical Center
Contraception Behavior
Hormonal Contraceptive Health Education for Adolescent Males
Prospective randomized control trial of an educational electronic application on female hormonal contraception for adolescent males in the pediatric emergency department.
- Trial name
- NCT03400410
- Testing
- Education Arm
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
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