Clinical trials: Emergency Departments
Suicide Attempts
Epidemiology of Acute Self-poisoning in Emergency Services in France
Acute self poisoning is a leading cause of suicide attempts and leads to frequent emergency department visits. However, the exact epidemiology of acute self poisoning is not known.
- Trial name
- EpiTox (NCT02518386)
- Testing
- No intervention
- Volunteers
- 700 people
- Sponsor
- University Hospital, Grenoble
ST Elevation Myocardial Infarction
Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During Emergency PCI
This study is aimed to investigate if the bivaliruding with prolonged full dose infusion after PCI is superior to heparin alone in reducing 30-day mortality or major bleeding for patients with STEMI treated with emergency PCI.
- Trial name
- BRIGHT-4 (NCT03822975)
- Testing
- Bivalirudin, unfractionated Heparin
- Where
- 85 sites in China
- Volunteers
- 6,016 people
- Sponsor
- Shenyang Northern Hospital
Stroke, Ischemic
Regional Strategy for Transfer for Mechanical Thrombectomy
A mono-centre observational study with the aim of compare clinical outcome at 3 month on patients admitted with recent cerebral infarct and intracranial large vessel occlusion in the anterior circulation who are eligible for…
- Conditions
- Stroke, Ischemic, Large Vessel Occlusion
- Trial name
- START (NCT04046757)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
CPAP Ventilation, COVID-19
Early CPAP in COVID-19 Patients With Respiratory Failure.
The study aims at clarifying whether early treatment with continuous positive airway pressure (CPAP) ventilation is able to reduce the need for intubation or death in patients visiting an emergency department (ED) with known or…
- Conditions
- CPAP Ventilation, COVID-19, Emergency Departments
- Trial name
- EC-COVID-RCT (NCT04326075)
- Testing
- CPAP treatment
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Emergencies
Comparison of Propofol-fentanyl and Midazolam-fentanyl for Conscious Sedation
Sixty patients who refer to the emergency ward and need any painful procedure in the ward are randomized into 2 groups. One group is sedated before the procedure using propofol-fentanyl and the other with midazolam-fentanyl, with…
- Trial name
- NCT01749579
- Testing
- Propofol, Midazolam, Fentanyl
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Palliative Medicine, Palliative Care
Palliative Care Needs Among Elderly People at Emergency Department
Aim: To assess what proportion of all patients over the age of 75 who seek care at the emergency department have palliative care needs and whether these are documented in the patient's medical record.
- Conditions
- Palliative Medicine, Palliative Care, Elderly Person
- Trial name
- NCT05883696
- Testing
- Swedish Palliative Care Guide (S-PCG)
- Where
- 2 sites in Sweden
- Volunteers
- 204 people
- Sponsor
- Region Skane
Surgical Site Infection, Length of Stay
Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy
Post-operative wound complications in abdominal surgery have a major impact on patient outcomes and the real impact of Closed incision negative pressure therapy (CINVt) is not clear in the literature moreover concerning its…
- Conditions
- Surgical Site Infection, Length of Stay, Seroma, Hematoma
- Trial name
- CiPNT/SSI (NCT04496180)
- Testing
- Closed incision negative pressure therapy versus standard dressing after emergency abdominal laparotomies
- Volunteers
- 334 people
- Sponsor
- University Hospital, Geneva
Emergency Patients
Management Standard of Bone Marrow Infusion in Acute and Critical Patients
As the spike in the number and severity of patients with critical patients, then quickly effective transfusion treatment demand becomes more and more serious, and the pattern of infusion pathways have traditionally used already…
- Trial name
- NCT04951596
- Testing
- Investigate the current situation
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Septic Shock
SQUEEZE Trial: A Trial to Determine Whether Septic Shock Reversal is Quicker in Pediatric Patients Randomized to an Early Goal Directed Fluid Sparing Strategy vs. Usual Care
The purpose of the SQUEEZE Trial is to determine which fluid resuscitation strategy results in the best outcomes for children treated for suspected or confirmed septic shock.
- Trial name
- SQUEEZE (NCT03080038)
- Testing
- Fluid Sparing Resuscitation Strategy
- Where
- 8 sites in Canada
- Volunteers
- 406 people
- Sponsor
- McMaster University
Diverticulitis
Is It So Hard To Predict Complicated Diverticulitis?
Is It So Hard To Predict Complicated Diverticulitis? Objective: Acute diverticulitis (AD) is a frequent cause of abdominal pain leading to emergency department visits.
- Trial name
- NCT07322926
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Post Traumatic Stress Disorder, Psychiatric Issue
Predictive Factors of PTSD in Adults Admitted to an Emergency Service
After trauma or stress factor like death exposition, serious injuries or sexual violence, some patients may develop stress reaction characterized by the presence of various symptoms among different categories (reviviscence…
- Trial name
- ISSUE (NCT03615014)
- Testing
- Filling questionnaires
- Where
- 5 sites in France
- Volunteers
- 460 people
- Sponsor
- Hospices Civils de Lyon
Language Discordance
Cost Effectiveness of Language Services in Hospital Emergency Departments (EDs)
Numerous studies suggest that the use of in-person, professionally trained medical interpreters can reduce health care costs associated with diagnosing and treating patients with limited English proficiency.
- Trial name
- NCT01041014
- Testing
- Professional medical interpreter
- Where
- 2 sites in United States
- Volunteers
- 447 people
- Sponsor
- Mathematica Policy Research, Inc.
Food Safety, Nutritive Value
Improving The Safety And Nutritional Adequacy Of The Home Food Supply Of Elderly Recipients Of Home Delivered Meals
Rutgers University will partner with the Meals on Wheels America (MOWA) and affiliated agencies in five states to conduct a study designed to improve food safety nutrition and emergency preparedness among homebound elderly…
- Conditions
- Food Safety, Nutritive Value, Homebound Persons, Frail Elderly
- Trial name
- NCT02719626
- Where
- 7 sites in United States
- Volunteers
- 740 people
- Sponsor
- Rutgers, The State University of New Jersey
Traumatic Brain Injury
Traumatic Brain Injury - Knowledge Translation
Blunt head trauma (BHT) accounts for >450,000 emergency department (ED) visits for children annually in the US. Fortunately, >95% of head trauma in children is minor in nature.
- Trial name
- TBI-KT (NCT01453621)
- Testing
- Computerized clinical decision support
- Where
- United States
- Volunteers
- 28,669 people
- Sponsor
- Columbia University
TO STUDY EMERGENCY CANCER PAIN PATTERNS AND TREATMENT ADEQUACY.
A Observational Study of Assessment and Treatment Adequacy of Emergency Cancer Pain in Tertiary Cancer Hospital
EMERGENCY CANCER PAIN MANAGEMENT HAS BEEN INCONSISTENT AND INADEQUATE ACROSS THE GLOBE. THIS STUDY AIMS TO KNOW EMERGENCY ROOM CANCER PAIN PATTERNS AND TREATMENT ADEQUACY IN TERTIARY CARE CANCER HOSPITALS.
- Trial name
- NCT01635478
- Volunteers
- 100 people
- Sponsor
- Tata Memorial Hospital
Sepsis
Change in MAPSE During Treatment of Sepsis
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems.
- Trial name
- NCT05634733
- Testing
- Treatment of Sepsis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Emergency Contraception
A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions
This study is designed to assess whether consumers select and use ella® (ulipristal acetate 30mg), an emergency contraceptive, in a manner consistent with the OTC package directions in an OTC-like setting.
- Trial name
- LIBRella (NCT03208985)
- Testing
- Use Phase (Ulipristal Acetate, 30 mg)
- Where
- 34 sites in United States
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Critical Illness
Validation of an Early Warning Score Based Triage System in the Emergency Department
At Bispebjerg Hospital we have introduced an Early Warning Score based triage system , called Bispebjerg Early Warning Score (BEWS), in order to identify critically ill patient on arrival at the emergency department.
- Trial name
- NCT01243021
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Bispebjerg Hospital
Odontalgia, Toothache
CBD for Dental Pain
The purpose of this study is to evaulate CBD as a therapeutic approach for dental pain. Eligible subjects presented with emergency dental pain will be give a single dose of Epidiolex (FDA-approved CBD) or placebo and will be…
- Trial name
- NCT04642404
- Testing
- Epidiolex 100 mg/mL Oral Solution
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Dyspnea, Chest Pain
Contactless Ultrasound Data Acquisition in Emergency Departments to Discriminate the Origin of Dyspnea and Chest Pain
PAnDA-One is a prospective, multicenter, interventional study (10 centers, France) aimed at developing and validating a diagnostic support algorithm based on the ADx-One medical device, which non-invasively acquires thoracic…
- Trial name
- PAnDA-One (NCT07653204)
- Testing
- All patients from both groups will be imaged with airborne ultrasound device
- Where
- France
- Volunteers
- 2,500 people
- Sponsor
- Austral Diagnostics
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