Clinical trials: Emergency Departments
Mitochondrial Diseases
EPI-743 for Mitochondrial Respiratory Chain Diseases
This study will evaluate the safety and efficacy of EPI-743 in participants with severe mitochondrial respiratory chain diseases who are considered to be within 90 days of end-of-life care.
- Trial name
- NCT01370447
- Testing
- EPI-743
- Where
- 16 sites in United States
- Sponsor
- PTC Therapeutics
Acute Coronary Syndrome, Chest Pain
Randomized Investigation of Chest Pain Diagnostic Strategies
Clinical decision units (CDUs) improve resource utilization and are a recommended care option by the American College of Cardiology / American Heart Association, but are underutilized in non-low risk chest pain patients due to…
- Trial name
- NCT01035047
- Testing
- Clinical decision unit care, coupled with cardiac MRI
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Wake Forest University Health Sciences
Chest Pain
The BEACON Registry: Best Expert Agreement for Care of Occult Myocardial Infarction (MI) Nationally
The purpose of this registry is to assess and improve the process of care and health outcomes of patients presenting to the Emergency Department with chest pain suspected to be of cardiac origin.
- Trial name
- BEACON (NCT00560248)
- Where
- United States
- Volunteers
- 1,897 people
- Sponsor
- The Cleveland Clinic
Chest Pain
Rapid Diagnosis of Patients With Chest Pain During the Covid-19 Outbreak (My-ABCDE)
During the outbreak of COVID-19, among patients with chest tightness and chest pain as the main symptoms in major medical institutions in Shanghai, China, the past medical history and rapid testing were used to quickly identify…
- Trial name
- My-ABCDE (NCT05394038)
- Testing
- None，observational study.
- Where
- China
- Volunteers
- 2,218 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Perforated Viscus, Intestinal Obstruction
Acute High-risk Abdominal Surgery Study - an Optimized Perioperative Course
The objective of this study is to implement an optimized perioperative course for patients undergoing acute high-risk abdominal surgery in order to improve the outcome.
- Trial name
- AHA (NCT01899885)
- Testing
- AHA (Acute Highrisk Abdominalsurgery): Optimized Course
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Hvidovre University Hospital
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Postpartum Hypertension Study
The purpose of this study is to assess which blood pressure medication (intravenous labetalol or oral nifedipine) works better in treating severely elevated blood pressure in women who have just delivered a baby.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
- Trial name
- NCT05139238
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Sarcopenia
Evaluation of Sarcopenia in Elderly at the Emergency Department
The goal of this observational study is to evaluate in elderly patients for the frequency of sarcopenia and its relationship with mortality in a university hospital. The main questions it aims to answer are; 1.
- Trial name
- NCT05567549
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ege University
All Eligible ED Patients (Not Limited to a Particular Condition)
Juice Preference in the Emergency Department
ED patients who are able to drink juice will be approached and asked their beverage preference.
- Trial name
- JUICED (NCT02506478)
- Testing
- Beverage procurement
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- Hennepin Healthcare Research Institute
Sedation
Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
This is a clinical trial of propofol and alfentanil as agents for moderated procedural sedation in patients undergoing sedation in the emergency department (ED).
- Trial name
- NCT00997126
- Testing
- Propofol, Alfentanil
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Hennepin Healthcare Research Institute
Chronic Back Pain, Degenerative Disc Disease Lumbar
CELZ-201-DDT for the Treatment of Chronic Lower Back Pain
CELZ-201-DDT is an investigational (experimental) cell therapy currently being studied for people with degenerative disc disease who have chronic lower back pain.
- Trial name
- ADAPT (NCT07137559)
- Testing
- CELZ-201-DDT
- Sponsor
- Creative Medical Technology Holdings Inc
Fall Patients
Older falleRs : From Emergency to Geriatric Network
The fall is a complex process associated with high morbidity and mortality, with an institutionalization rate of up to 40% and a major socio-economic impact. The prevalence of falls increases with age.
- Trial name
- OREGoN (NCT03488615)
- Where
- France
- Volunteers
- 204 people
- Sponsor
- University Hospital, Angers
Nasogasrtic Tube Insertion
Intranasal Lidocaine Spray Versus Nasogastric Tube Administration in the Emergency Room
The goal of this clinical trial is to evaluate whether 10% intranasal lidocaine spray reduces pain and improves the success rate of nasogastric tube (NGT) insertion compared to placebo in adult emergency department patients.
- Trial name
- Lidocaine (NCT07103915)
- Testing
- Lidocaine 10% Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Emergencies
Effect of Covid-19 Pandemic on Emergency Surgery Practice
A retrospective study at a tertiary university hospital to determine the effect of the COVID-19 pandemic on the emergency surgery practice in the hospital.
- Trial name
- NCT04815135
- Testing
- Observational study
- Where
- Jordan
- Volunteers
- 344 people
- Sponsor
- Ibrahim Khrais
Intussusception, Emergencies
Point-of-Care Ultrasonography for Intussusception
Pediatric emergency medicine (PEM) physicians are increasingly utilizing point-of-care ultrasound (POCUS). There is currently limited data regarding POCUS evaluation for intussusception in pediatric patients.
- Trial name
- NCT03360643
- Testing
- Point-of-care ultrasound prior to radiology ultrasound, Radiology-performed ultrasound
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Pain
Safety and Efficacy of Patient Controlled Analgesia in the Emergency Department
The aims of this study are to assess efficacy and safety of patient-controlled analgesia (PCA) when applied to the Emergency Department setting and to compare the efficacy and safety of two PCA dosing regimens.
- Trial name
- NCT00910208
- Testing
- Patient-controlled analgesia, morphine
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Albert Einstein College of Medicine
Acute Coronary Syndrome, Chest Pain
Are Serial Electrocardiograms Additive to SeriAl Second-generations Troponins in Predicting Acute CoronAry Syndromes in PatienTs With Undifferentiated cHest Pain
Our research will examine whether the presence or absence of serial electrocardiogram (ECG) changes aids in reclassifying participants' risk for major adverse cardiac events (MACE) over and above serial blood testing.
- Trial name
- ASAP Cath (NCT01953276)
- Testing
- Serial Electrocardiograms
- Where
- United States
- Volunteers
- 382 people
- Sponsor
- Wake Forest University Health Sciences
Renal Colic
Transcutaneous Electrical Nerve Stimulation Treatment of Renal Colic
The aim of the present trial was to investigate the analgesic efficacy and safety of Transcutaneous electrical nerve stimulation treatment in patients with renal colic within the emergency department.
- Trial name
- NCT03237208
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University Research Hospital
Acute Stroke
Risk Factors of Conversion From Local to General Sedation in Endovascular Stroke Therapy
Thrombectomy is now the standard of care of revascularization in acute ischaemic stroke. Data tend to show that final neurologic outcome is superior if the thrombectomy procedure was performed under conscious sedation.
- Trial name
- AMAS (NCT02895776)
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Appendicitis
Management of Acute Appendicitis Pain in the Emergency Department
This study aims to compare the effectiveness of TAP (Transversus Abdominal Plane) block, ESPB (Erector Spinal Plane Block), and tramadol in preoperative pain management for patients diagnosed with acute appendicitis and…
- Trial name
- NCT06808087
- Testing
- Transversus abdominis plane blockage, Erector spinae plane blockage, Tramadol
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Dehydration
Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children
The aim of the study is to evaluate the safety, effectiveness and ease of use of subcutaneous (SC) rehydration using HYLENEX-augmented SC infusion of fluids and electrolytes for the rehydration of pediatric patients with mild to…
- Trial name
- INFUSE-PR (NCT00477152)
- Testing
- hyaluronidase (human recombinant)/rehydration fluid
- Volunteers
- 52 people
- Sponsor
- Baxter Healthcare Corporation
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