Clinical trials: Emergency Departments
Pain
Pain Control After Cardiac Surgery Using Intravenous Acetaminophen
Evaluate the efficacy of IV acetaminophen; compared to a placebo, in reducing opioid consumption and/or pain intensity scores after cardiac surgery.
- Trial name
- NCT01822821
- Testing
- IV Acetaminophen
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Acute Coronary Syndrome, STEMI
Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With Chest Pain
Accurate detection of a heart attack (an acute myocardial infarction) is one of the most pressing needs in medicine. Recordings of the electrocardiogram (ECG) (electrical activity of the heart) are one of the first tools used to…
- Conditions
- Acute Coronary Syndrome, STEMI, NSTEMI, Unstable Angina
- Trial name
- NCT01185899
- Where
- Israel
- Volunteers
- 324 people
- Sponsor
- Ori Galante
Pulmonary Embolism
Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE)
This study is a quality improvement project to evaluate health care management of pulmonary embolism (PE) patients. The researchers are testing an intervention to determine if it prevents unnecessary hospital admissions.
- Trial name
- NCT06312332
- Testing
- Pulmonary Embolism (PE) Care in Emergency Department (ED)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan
Intubation
Effect of Upright Patient Positioning on Intubation Success
Endotracheal intubation is most commonly taught and performed with the patient supine. Recent literature suggests that elevating the patient's head to a more upright position may decrease peri-intubation complications.
- Trial name
- NCT02885298
- Testing
- Upright intubation
- Volunteers
- 232 people
- Sponsor
- Indiana University
Femur Fracture, Pain, Joint
Emergency Department Management of Femur Fractures
Comparison of emergency department management of patients presenting with isolated hip fracture: comparison of methods used in pain management, monitoring, and treatment; comparison of hospitalization durations; comparison of…
- Conditions
- Femur Fracture, Pain, Joint, Analgesia
- Trial name
- NCT06531564
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- Saglik Bilimleri Universitesi
Pregnancy in Adolescence, Counseling
Reducing Adolescent Pregnancy
This multi-site study is employing a brief contraception counseling intervention in the Emergency Department (ED) to shed light on factors that affect decision making as well as barriers and facilitators to conception initiation…
- Conditions
- Pregnancy in Adolescence, Counseling, Contraception Behavior
- Trial name
- NCT04120376
- Testing
- Contraception Counseling
- Where
- 2 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Arrhythmias, Cardiac, Heart Diseases
Efficacy and Safety Study of Azimilide on the Incidence of Cardiovascular Hospitalizations/Emergency Department Visits or Cardiovascular Death in Patients With an Implantable Cardioverter Defibrillator (ICD) (SHIELD-2)
This study will evaluate the efficacy and safety of Azimilide on the incidence of cardiovascular hospitalizations, cardiovascular emergency department visits or cardiovascular death in patients with Implantable Cardioverter…
- Conditions
- Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases, Implantable Cardioverter Defibrillator
- Trial name
- SHIELD-2 (NCT01464476)
- Testing
- Azimilide Dihydrochloride
- Where
- 138 sites in United States, Belgium and 11 more
- Volunteers
- 240 people
- Sponsor
- Forest Laboratories
Acute Effects of EMWs Emitted by Cell Phones
Acute Effects of Cell Phone Exposure on Immediate Attention Levels and Concentration of Emergency Physicians
To investigate the acute effects of cell phone exposure on immediate attention levels and concentration of emergency department physicians
- Trial name
- NCT03239925
- Testing
- Electromagnetic field of cell phone in ''on'' mode., Electromagnetic field of cell phone in 'off' mode.
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Emergency Service, Hospital
Nudging High Emergency Department Utilizers to Consider Non-emergent Healthcare Resources
The goal of this campaign is to reduce unnecessary ED visits by providing patients who are high ED utilizers (with a visit of any acuity) with alternative resources to manage their health outside of the ED.
- Trial name
- NCT06818825
- Testing
- Automated interactive messages, Live outreach
- Where
- United States
- Volunteers
- 1,126 people
- Sponsor
- Geisinger Clinic
Opioid Use Disorder
Houston Emergency Opioid Engagement System
The Houston Emergency Response Opioid Engagement System (HEROES) is a community-based research program integrating assertive outreach, medication-assisted treatment, behavioral counseling, peer recovery support, and paramedic…
- Trial name
- HEROES (NCT03396276)
- Testing
- Suboxone, Brief counseling in the ED, Referral to outpatient treatment
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
Emergency Department Procedural Sedation, Fracture Reduction
Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia
When patients come to the Emergency Department with injuries and infections they often need to have painful procedures performed that are essential to allowing them to recover.
- Conditions
- Emergency Department Procedural Sedation, Fracture Reduction, Abscess Incision and Drainage, Electrical Cardioversion
- Trial name
- NCT01211158
- Testing
- Ketofol, Propofol alone
- Where
- Canada
- Volunteers
- 284 people
- Sponsor
- Lions Gate Hospital
PTSD, Physical Injury
IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems
This study evaluates two readily implementable approaches to the delivery of transitional care for injured patients treated emergently in US trauma care systems.
- Trial name
- TSOS 7 Peer (NCT03569878)
- Testing
- Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Text Messaging
Text Messaging Follow-up From ED
Ensuring follow-up for patients after discharge from the emergency department (ED) has long been a concern for ED care providers. The current technology of text messaging may be able to assist us in improving follow-up rates.
- Trial name
- NCT03370978
- Testing
- Text Messaging
- Where
- United States
- Sponsor
- University of Iowa
Emergency Medicine, Diagnostic Errors
Diagnostic Accuracy of Two Large Language Models in Turkish Emergency Department Anamnesis Notes
This retrospective diagnostic accuracy study evaluates two large language models - GPT-4.1 (gpt-4.1-2025-04-14; OpenAI) and Claude Sonnet 4.6 (claude-sonnet-4-6; Anthropic) - as retrospective coding-quality instruments applied to…
- Conditions
- Emergency Medicine, Diagnostic Errors, Artificial Intelligence (AI) in Diagnosis
- Trial name
- LLM-ED-DX-TR (NCT07632859)
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Geriatrics
Continuity of the Therapeutic Limitation Code: Analysis of the Variables of Admission in the Emergency Service That Are Associated With a Therapeutic Limitation Upon Exit
Demographically, the geriatric population is expanding. It is also increasingly found in the emergency services.However, emergency services are not designed to accommodate these patients, whose needs are specific.
- Trial name
- NCT02682979
- Testing
- Medical files analysis
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Stress
Box Breathing Versus Foot Reflexology on Physiological and Psychological Stress Indicators in Emergency Physicians
This study aims to compare between the effect of box breathing and foot reflexology on physiological and psychological stress indicators in emergency physicians.
- Trial name
- NCT07705854
- Testing
- Box Breathing, Foot Reflexology
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Illness
Patient Navigation for Medicaid Frequent ED Users
A large proportion of frequent ED users have Medicaid insurance. The purpose of this study is to evaluate the effectiveness of patient navigation for reducing Emergency Department (ED) visits and hospitalizations and improving…
- Trial name
- NCT01797068
- Testing
- Patient Navigator, Standard of Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Acute Coronary Syndrome, Coronary Artery Disease
Pilot Safety Study of Coronary CTA for the Diagnosis of Acute Coronary Syndrome in the Emergency Room
The Diagnosis of acute coronary syndrome in patients presenting with acute chest pain is problematic when both, electrocardiogram and serum troponins are normal.
- Conditions
- Acute Coronary Syndrome, Coronary Artery Disease, Cardiac Death, Myocardial Infarction
- Trial name
- NCT01682096
- Testing
- computed coronary angiography, Exercise stress echocardiography
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- José Ortiz
Cannabis Use
Brief Intervention Combined With Health Coaching Via Social Media for Cannabis Use
The purpose of the study is to develop and test social media interventions to help young people increase well-being and reduce risky behaviors.
- Trial name
- NCT04316741
- Testing
- Snapcoach
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Michigan
Cutaneous Abscess
Trial of Abscess Drainage Techniques
Comparing the outcome of traditional incision and drainage with a larger skin incision with or without gauze packing of cutaneous abscess in pediatrics versus a new minimally invasive incision and drainage with two small…
- Trial name
- NCT02545946
- Testing
- vessel loop, traditional I&D with or without packing
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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