Clinical trials: Emergency Departments
Emergency
Variation IGFBP7 Markers and TIMP2 Induced by Injection of Contrast Iodized Drug at the Intensive Care Patient
Multicenter, prospective, uncontrolled study to evaluate variations in urinary concentrations of TIMP-2 and PCI IGFBP7 induced injection during a CT scan in intensive care patient.
- Trial name
- ContraCHECK (NCT02881710)
- Testing
- contrast product used to assess biomarkers variations
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Diabetic Ketoacidosis
Use of Insulin Glargine to Treat Diabetic Ketoacidosis
The purpose of this study is to determine the effects of the addition of insulin glargine during the early phase of moderate to severe Diabetic Ketoacidosis (DKA) in children.
- Trial name
- NCT00179127
- Testing
- glargine, saline
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Vanderbilt University Medical Center
Emergency Surgical Procedures, Postoperative Pain
Postoperative Progressive Relaxation Exercises for Pain and Anxiety After Emergency Surgery
This randomized controlled trial investigated the effectiveness of postoperative progressive relaxation exercises (PRE) on pain, anxiety, and physiological parameters among adult patients undergoing emergency general surgery.
- Conditions
- Emergency Surgical Procedures, Postoperative Pain, Postoperative Anxiety
- Trial name
- PRE-ES (NCT07301073)
- Testing
- Progressive Relaxation Exercises (PRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Agri Ibrahim Cecen University
Hepatitis C Virus (HCV), Hepatitis C Virus (HCV) Infection
Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System
The goal of this observational study is to develop, implement, and evaluate a machine learning algorithm-based Hepatitis C Emergency Department (HepC-EnD) screening tool for use in emergency departments (EDs) to identify patients…
- Conditions
- Hepatitis C Virus (HCV), Hepatitis C Virus (HCV) Infection, HIV (Human Immunodeficiency Virus)
- Trial name
- HepC-EnD (NCT07406490)
- Testing
- Physician-Initiated Screening (Conventional Screening), FOCUS (Universal Screening), HepC-EnD (Targeted Screening)
- Where
- 3 sites in United States
- Volunteers
- 6,466 people, healthy volunteers welcome
- Sponsor
- University of Florida
Comparative Effectiveness Research
Geriatric Team in ED: Effects on Rate of Hospitalization and on Community Health Management of Elderly (GerED-21)
The Ger-ED Intervention study focuses on early assessment and intervention in the emergency department (ED) by a specialized geriatric team, which includes a geriatrician, a nurse with expertise in geriatrics and continuity of…
- Trial name
- GerED-21 (NCT06788210)
- Testing
- Multiprofessional Geriatric Emergency Team applied front-door CGA to identify patients who require inpatient care and those who can safely be discharged.
- Where
- Italy
- Volunteers
- 624 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Patient Presented With Acute Abdomen, Patient Undergoing Urgent GIT Surgery
Conventional VS Enhanced Recovery After Surgery Protocols in Emergency GIT Surgery
Although the ERAS program is widely used in elective procedures in many surgical subspecialties, the place of this program in emergency surgery remains uncertain probably because of the significant challenges in applying all ERAS…
- Trial name
- NCT04584060
- Testing
- ERAS protocols, Early oral feeding, Prophylaxis against DVT
- Volunteers
- 60 people
- Sponsor
- Assiut University
Severe Trauma
Evaluation of the Vittel Criteria for Pre-hospital Triage of Severe Trauma Patients in the French West Indies and in French Guiana
Severe trauma is a public health problem because it is the leading cause of death in young people and the third leading cause of death in France for all ages.
- Trial name
- TRAUMA-DOM (NCT06580262)
- Testing
- Routine care
- Where
- 2 sites in France
- Volunteers
- 700 people
- Sponsor
- University Hospital Center of Martinique
Acute Gastroenteritis
Ondansetron Oral Versus Orally Disintegrating Tablets (ODT)
In children aged 3 months to 10 years who present to the Pediatric Emergency Department (PED) with recent, significant vomiting and moderate dehydration, is treatment with Ondansetron Orally Disintegrating Tablet (ODT) better…
- Trial name
- NCT02174874
- Where
- Canada
- Volunteers
- 462 people
- Sponsor
- Dr. Graham Thompson
Shock
Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Fluid Responsiveness During the Initial Management of Shock in Patients Admitted to the Emergency Department
Assessing the response to vascular filling in shock is a challenge in emergency medicine. The mitral annulus velocity measured by tissue Doppler (E') has recently been characterized as sensitive to the preload conditions of a…
- Trial name
- EVO-E' (NCT05888974)
- Testing
- Cardiac ultrasonography
- Where
- France
- Volunteers
- 187 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Low Back Pain, Shoulder Pain
An Efficacy and Safety Study of Tramadol Hydrochloride-Paracetamol in Treatment of Moderate to Severe Acute Neck-Shoulder Pain and Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of tramadol hydrochloride-paracetamol tablets in treatment of moderate (medium level of seriousness) to severe (very serious) acute neck, shoulder and low back pain…
- Conditions
- Low Back Pain, Shoulder Pain, Neck Pain
- Trial name
- NCT01843660
- Testing
- Tramadol HCl-Paracetamol
- Volunteers
- 1,059 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Primary Health Care
Impact of a Community-Based Primary Health Care Project on the Inappropriate Use of Emergency Medical System in Bergamo
The goal of this study is to reduce the inappropriate use of the Emergency Medical System in Bergamo. The main question it aims to answer is: can a Community-Based Primary Health Care Project impact on the use of the Emergency…
- Trial name
- PHC-BG_EMS (NCT06862882)
- Testing
- Community-Based Primary Health Care
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione San Giuliano Onlus
Acute Respiratory Failure
Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial
The Hyperangulated versus Standard Geometry Laryngoscope Blade (ANGLE) Trial is a multi-center, non-blinded, parallel-group, randomized clinical trial evaluating the effect of use of a hyperangulated video laryngoscope blade…
- Trial name
- ANGLE (NCT07223762)
- Testing
- Hyperangulated video laryngoscope blade, Standard geometry video laryngoscope blade
- Where
- 19 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Vanderbilt University Medical Center
Endotracheal Intubation, Deep Sedation
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine.
- Trial name
- ANACONDA (NCT04141267)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Sickle Cell Disease
A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis
This study is being done to learn more about a possible new treatment for pain episodes (called vaso-occlusive crises or VOCs) in children, teens, and young adults with sickle cell disease (SCD).
- Trial name
- NCT06989567
- Testing
- L-citrulline
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Asthma
Pulmicort Respules on Relapse Rates After Treatment in the ED
The purpose of this study is to see if the addition of budesonide to oral corticosteroids will result in a decrease in relapse rates compared to oral corticosteroids alone in children who are discharged from the ED after an…
- Trial name
- Budesonide (NCT00584636)
- Testing
- pulmicort respules
- Where
- United States
- Sponsor
- Phoenix Children's Hospital
Emergencies
Evaluation of the COVID-19 Infection Response in Patients Admitted to the Emergency Department for Dyspnea
This research aims to improve our knowledge of the epidemiology of patients consulting in the COvid-19 Possible REspiratory Units (RECOP unit). Indeed, the epidemic linked to COVID-19 affects France and impacts its health system.
- Trial name
- EPRICOD (NCT04422587)
- Testing
- RECOP unit patient
- Where
- France
- Volunteers
- 1,860 people
- Sponsor
- University Hospital, Toulouse
Distal Radius Fracture
Bier's Block Versus Systemic Analgesia
Background: There are three methods for procedural sedation in upper extremity traumas; systemic, regional and local anesthesia. There is controversy in the literature regarding the method of choice for this purpose.
- Trial name
- NCT03349216
- Testing
- Intravenous Regional Anesthesia, Systemic Analgesia
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Colles' Fracture
A Trial Comparing Circumferential Casting Versus Splinting in Displaced Colles' Fractures
Displaced fractures of the distal radius requiring closed reduction (otherwise known as Colles fractures) are common in the emergency department.
- Trial name
- NCT00704743
- Testing
- Cylindrical cast, Modified sugar tong cast, Volar dorsal splint
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Mental Health Disorder, Mental Health Impairment
An Innovative Mental Health Virtual Ward: Evaluation of Patient-Centered Outcomes
The goal of this study is to evaluate if admission to the Mental Health Virtual Ward (MH vWard) for mental health crisis stabilization is having a meaningful positive impact on patient reported outcomes and healthcare…
- Conditions
- Mental Health Disorder, Mental Health Impairment, Psychiatric Emergency, Crisis; Emotional
- Trial name
- NCT06526026
- Testing
- Virtual crisis stabilization support with a multi-disciplinary team
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Manitoba
Acute Heart Failure, Emergencies
Risk Stratification Using MEESSI-AHF Scale in ED and Impact on AHF Outcomes
Evaluate the impact the application of the MESSI-AHF scale (a risk stratification scale specifically derived and validated in patients diagnosed with acute heart failure, AHF) in decision making (admission vs.
- Trial name
- MEESSI (NCT05919225)
- Testing
- Risk stratification before decision-making about patient hospitalization or discharge
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people
- Sponsor
- Hospital Clinic of Barcelona
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