Clinical trials: Emergency Departments
Fecal Impaction of Colon
PoCUS Diagnostic Accuracy for Fecal Impaction in the Emergency Department: A Prospective Study
Many medical and paramedical specialties regularly use point-of-care ultrasound (PoCUS) in clinical practice. The diagnosis of fecal impaction is quite common in the elderly living in nursing homes with a prevalence of 47.3%.
- Trial name
- NCT06333106
- Testing
- POCUS diagnostic value
- Where
- 6 sites in Belgium
- Volunteers
- 247 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Laceration, Anxiety
Intranasal Dexmedetomidine vs Intranasal Midazolam as Anxiolysis Prior to Pediatric Laceration Repair
The objective of this research study is to show superiority of intranasal dexmedetomidine to intranasal midazolam as anxiolysis prior to pediatric laceration repairs.
- Trial name
- NCT02168439
- Testing
- Dexmedetomidine, Midazolam
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
COVID-19, Inflammatory Response
Severe COVID-19 Infection in Children Presenting to EDs in Israel and England
Even though the COVID-19 pandemic is no longer at its peak, the threat still lingers. Engaging in prospective surveillance studies will enable us to monitor the disease and prepare for any potential resurgence.
- Trial name
- SPICE (NCT06434701)
- Testing
- Nasopharyngeal swab sampling for COVID-19
- Where
- 6 sites in Israel
- Volunteers
- 500 people
- Sponsor
- Hadassah Medical Organization
Contraception
Drospirenone-only Pill as Emergency Contraception
Emergency contraception (EC) provides an additional measure to help prevent pregnancy after unprotected intercourse or contraceptive failure.
- Trial name
- NCT05675644
- Testing
- Drospirenone-only pill
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Acute Aortic Syndrome
Aortic Dissection Detection Risk Score With D-dimer to Rule-Out Acute Aortic Syndrome
The goal of this study is to evaluate the safety of integrating the Aortic Dissection Detection Risk Score (ADD-RS) and D-dimer testing for ruling out acute aortic syndrome (AAS) in the emergency department (ED).
- Trial name
- NCT07640334
- Testing
- D-dimer test
- Where
- 2 sites in Hong Kong
- Volunteers
- 746 people
- Sponsor
- Chinese University of Hong Kong
Falls-Risk
Effectiveness of an Automated Falls-Risk Screening and Referral Tool in the Emergency Department (ED)
The purpose of this retrospective cohort study is to evaluate the effectiveness of an EHR-based clinical decision support system (CDS) for automatically screening older adult ED patients for risk of future falls and providing ED…
- Trial name
- NCT05810064
- Testing
- Falls-Risk Clinical Decision Support (CDS) Tool
- Where
- 3 sites in United States
- Volunteers
- 36,205 people
- Sponsor
- University of Wisconsin, Madison
Inguinal Hernia
Predictability of the Ability to Perform an Emergency Stop After Surgery for Inguinal Hernia
Several studies exist on patient performance in drive simulators especially around and after surgery. Recommendations concerning the ability to drive after inguinal hernia are scarce and so far do not offer conclusive results.
- Trial name
- NCT03808012
- Testing
- Braking performance in a brake simulator
- Where
- Germany
- Sponsor
- University Hospital Tuebingen
Hydronephrosis, Pyelonephritis
Bedside Ultrasonography in Acute Patients With Suspected Kidney Involvement
The aim of this study is to evaluate the accuracy and implications of the diagnoses and treatment determined by bedside ultrasonography (b-US) of the kidneys compared to current clinical assessment.
- Conditions
- Hydronephrosis, Pyelonephritis, Urosepsis
- Trial name
- NCT03873701
- Testing
- bedside ultrasonography
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- Odense University Hospital
Myocardial Infarction
Improving Door-to-Balloon Time in STEMI
The investigators prospectively determined the impact on median door-to-balloon time of a protocol mandating (1) emergency department physician activation of the catheterization lab and (2) immediate transfer of the patient to an…
- Trial name
- EHART (NCT00800163)
- Testing
- ED Activation/Immediate Transfer
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- St. Francis Hospitals & Health Centers
Asthma
Inhaled Steroids at Discharge After Emergency Department Visits for Children With Uncontrolled Asthma
Many children have asthma and this causes problems with their health. A lot of children with uncontrolled asthma use emergency departments for asthma care, and so this is an ideal place for an intervention for these children.
- Trial name
- NCT01881412
- Testing
- fluticasone, Standard Asthma Discharge Instructions
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Rhode Island Hospital
Hyperglycemia, Diabetes Mellitus
Management of Hyperglycemic Patients in Emergency Medicine Department
The main purpose of this study is how to manage hyperglycemic patients in emergency departments, to determine the conditions that require blood glucose regulation and to examine the prognosis of the patients in the next 30 days…
- Conditions
- Hyperglycemia, Diabetes Mellitus, Emergencies
- Trial name
- NCT04665128
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Derince Training and Research Hospital
Acute Coronary Syndrome
Early Risk Stratification in ED Chest Pain Patients
In the management of adult chest pain patients presenting to an Emergency Department (ED) with suspected acute coronary syndrome (ACS), we aimed to evaluate the diagnostic accuracy of the combined use of a modified Thrombolysis…
- Trial name
- NCT02364271
- Testing
- Thrombolysis in myocardial infarction score, routine blood test for hs-cTnT, HEART score
- Where
- China
- Volunteers
- 602 people
- Sponsor
- Chinese University of Hong Kong
Musculoskeletal Diseases, Low Back Pain
Front Line Agreement in Diagnosis and Treatment for Musculoskeletal Dysfunctions
Background: This randomized study, conducted from October to December 2023 in the emergency department of Bethesda Hospital Basel, Switzerland, investigated a new model of care for patients presenting with non-urgent…
- Conditions
- Musculoskeletal Diseases, Low Back Pain, Emergency Service, Hospital, Physical Therapy Modalities
- Trial name
- DirectPhysio (NCT07443098)
- Testing
- Intervention: ED - physiotherapist group, Control: resident physician group
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Bern University of Applied Sciences
Atrial Fibrillation, Atrial Flutter
RAFF5 Proposal: Improve the Quality and Safety of Patients Seen in the Emergency Department for Acute Atrial Fibrillation and Flutter
Acute atrial fibrillation (AF) and flutter (AFL) are the most common arrhythmias requiring management in the emergency department (ED).
- Trial name
- RAFF5 (NCT05468281)
- Testing
- Checklist implementation
- Where
- Canada
- Volunteers
- 1,108 people
- Sponsor
- Ottawa Hospital Research Institute
COVID-19, Headache Disorders
Impact of COVID-19 Pandemic on Headache Evaluations in the Pediatric Emergency Department
Background: To evaluate the impact of COVID-19 on evaluations in the pediatric emergency department (ED) because of headache as main symptom.
- Conditions
- COVID-19, Headache Disorders, Emergency Service, Hospital
- Trial name
- NCT06295003
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Emergency Colorectal Surgery in Ultra 80 Patients
Colorectal Emergencies in Elderly Patients.
Colon diseases can turn in a clinical emergency with the onset of some important complications. Some critical conditions are more common in aged patients because they are more frails.
- Trial name
- NCT05443386
- Testing
- colorectal surgery
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Foggia
Dehydration
Subcutaneous Recombinant Human Hyaluronidase: Workflow Analysis and Emergency Department Design
This is an observational study examining the workflow dynamics and training requirements that support effective use of subcutaneous hydration delivery (a newly FDA approved Baxter product) compared to standard intravenous…
- Trial name
- Hylenex-ED (NCT01020513)
- Sponsor
- University of California, San Diego
Stroke, Guillain-Barre Syndrome
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology
This study examines the use of an AI-powered virtual assistant for quickly identifying and handling neurological emergencies, particularly in places with limited medical resources.
- Conditions
- Stroke, Guillain-Barre Syndrome, Facial Palsy, Migraine
- Trial name
- AIDEN (NCT06334796)
- Testing
- Virtual Assistant
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Cellulitis, Wound Infection
Penicillin for the Emergency Department Outpatient Treatment of CELLulitis
The main objective of this study is to investigate the non-inferiority of oral flucloxacillin alone compared with a combination of oral flucloxacillin and phenoxymethylpenicillin for the emergency department directed outpatient…
- Conditions
- Cellulitis, Wound Infection, Abscess
- Trial name
- PEDOCELL (NCT02922686)
- Testing
- Flucloxacillin, Phenoxymethylpenicillin
- Where
- 5 sites in Ireland
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Acute Back Pain
Battlefield Acupressure for Acute Back Pain Management in the Emergency Department
Patients frequently present to the emergency department for treatment of acute pain. In the emergency department, analgesic medications, particularly opiates, are most often the primary and only means of treatment.
- Trial name
- ED (NCT07771686)
- Testing
- Battlefield auricular acupressure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hackensack Meridian Health
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