Clinical trials: Emergency Departments
Emergency Medical Services, Telemedicine
Effect and Safety of a Pediatric Triage Track on Hospital Visits and at the Public Medical Helpline 1813, Capital Region, Denmark
Children under three years old often fall ill. While most illnesses are mild, they often lead to worry which contributes to a high number of contacts with general practitioners and acute medical services such as the Medical…
- Conditions
- Emergency Medical Services, Telemedicine, Children, Triage
- Trial name
- NCT06722040
- Testing
- Implementation of a pediatric triage track
- Where
- Denmark
- Volunteers
- 244,000 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Hypobaric Hypoxia, Cognitive Deterioration
Effects of Acute Hypobaric Hypoxia Exposure on Neurocognitive Performance of Pre-hospital Emergency Service Providers
The study aims to evaluate the effects of acute hypobaric hypoxia on cognitive performance (H0: cognitive performance at 200 meters above sea level (asl) = cognitive performance at 3000 meters above sea level = cognitive…
- Conditions
- Hypobaric Hypoxia, Cognitive Deterioration, Emergency Medicine, Resuscitation
- Trial name
- NCT04138446
- Testing
- Altitude exposure in climate chamber
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Sedation and Analgesia, Side Effect of Drug
The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department
The purpose of this study is to evaluate the anti-emetic effect of oral ondansetron. For this evaluation, the investigators will perform a multi-center, double-blind, placebo-controled, randomized study.
- Trial name
- NCT01477242
- Testing
- Ondansetron
- Where
- South Korea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Surgical Site Infection, Surgical Wound
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients…
- Conditions
- Surgical Site Infection, Surgical Wound, Surgical Incision, Emergency Laparotomies
- Trial name
- NCT05989386
- Testing
- 0.9% saline solution, Povidone-iodine Swab
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Cancer
Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections
RATIONALE: White blood cells that have been treated in the laboratory may kill cells that are infected with cytomegalovirus. PURPOSE: This phase I trial is studying how well cytotoxic T cells work in treating patients who have…
- Trial name
- NCT00769613
- Testing
- cytomegalovirus IE-1-specific cytotoxic T lymphocytes, cytomegalovirus pp65-specific cytotoxic T lymphocytes, therapeutic allogeneic lymphocytes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Emergency Department, Clinical Pharmacist
Integrating the Clinical Pharmacists Into Emergency Department Teams
The "Emergency Department (ED) Pharmacist" is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations.
- Trial name
- ED-PHARM (NCT04722588)
- Testing
- Introducing clinical pharmacists to the interdisciplinary ED team.
- Where
- 3 sites in Norway
- Volunteers
- 30,888 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
Nonreassuring Fetal Status
Acute Tocolysis With Terbutaline for Suspected Fetal Distress
The trial was to determine the effect of administrating subcutaneous terbutaline prior to emergency caesarean delivery for suspected fetal distress
- Trial name
- NCT05326269
- Testing
- Terbutaline
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Smoking, Smoking Cessation
Deliver an Evidence-based Smoking Cessation Intervention for Smokers Attending A&E Departments in Hong Kong
This project aims to deliver an evidence-based smoking cessation intervention comprising the provision of brief cessation advice to smokers attending emergency departments and active referral to existing smoking cessation…
- Conditions
- Smoking, Smoking Cessation, Evidence-Based Nursing, Emergency Service, Hospital
- Trial name
- NCT03818360
- Testing
- an evidence-based smoking cessation intervention comprising brief advice plus active referrals
- Where
- Hong Kong
- Volunteers
- 1,603 people
- Sponsor
- The University of Hong Kong
Incisional Hernia, Emergency Laparotomy
Preemer Trial - Prophylactic Mesh Versus no Mesh in the Midline Emergency Laparotomy Closure for Prevention of Incisional Hernia: a Multi Center, Double-blind, Randomized Controlled Trial
244 patients, who have an emergency midline laparotomy for any gastrointestinal reason, will be randomized in a 1:1 ratio either to mesh group with a retrorectus prophylactic self-gripping mesh or to control group with 4:1 small…
- Conditions
- Incisional Hernia, Emergency Laparotomy, Midline Laparotomy, Hernia Prevention
- Trial name
- NCT04311788
- Testing
- Prophylactic self gripping mesh, Slowly absorbable continuous monofilament suture
- Where
- 7 sites in Finland
- Volunteers
- 109 people
- Sponsor
- University of Oulu
Syncope
Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Syncope is a common Emergency Department (ED) presentation but the underlying diagnosis is not apparent in 60% of patients after assessment and serious adverse event rate is 7% at one month with most having acute cardiovascular…
- Trial name
- PATCH-ED (NCT02683174)
- Testing
- Novel ambulatory patch (ZIO® XT Patch), BNP and hs-troponin I at 0 and 3 hours post ED attendance
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- NHS Lothian
Shoulder Dislocation
Propofol Target-Controlled Infusion in Emergency Department Sedation
There exists continued controversy over the use of propofol in Emergency Department procedural sedation, this is despite its widespread existence in clinical practice for at least a decade.
- Trial name
- ProTEDS (NCT03442803)
- Testing
- Target-Controlled Infusion
- Where
- 4 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Human Immunodeficiency Virus, Pre-Exposure Prophylaxis
Universal Test and Connect for HIV Service Delivery in South Africa
The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA).
- Conditions
- Human Immunodeficiency Virus, Pre-Exposure Prophylaxis, Emergency Department, South Africa
- Trial name
- UTC: SA (NCT06408142)
- Testing
- HIV testing, In-depth interview
- Where
- South Africa
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Migraine
Corticosteroids for Acute Migraine in the Emergency Department
This is an emergency department based randomized trial in which we compare two different treatment for migraine headache. The goal is to decrease the number of headache days during the week after ED discharge.
- Trial name
- NCT02847494
- Testing
- metoclopramide, Dexamethasone, methylprednisolone acetate
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Montefiore Medical Center
Ischemic Stroke
Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke
Patients presenting to the emergency department with acute ischemic stroke, who are are eligible for standard intravenous tPA therapy within 4.5 hours of stroke onset will be assessed for major vessel occlusion to determine their…
- Trial name
- EXTEND-IA TNK (NCT02388061)
- Testing
- Tenecteplase, Tissue Plasminogen Activator
- Where
- 18 sites in Australia, New Zealand
- Volunteers
- 202 people
- Sponsor
- Neuroscience Trials Australia
Emergency Contraception, Contraception
Depot Medroxyprogesterone Acetate as Emergency Contraception
Background: The prevalence of repeat unprotected intercourse after EC use in the same cycle demonstrate the need for more self-bridging emergency contraceptive options.
- Trial name
- NCT03395756
- Testing
- Depot-Medroxyprogestereone Acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Headache
Prospective ED Headache Cohort Study
The purpose of this study is to determine how often headaches recur and to learn how to predict continued suffering from headache after emergency department discharge.
- Trial name
- NCT00313703
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Montefiore Medical Center
Atrial Fibrillation
Relieving the Emergency Department by Using a 1-lead ECG Device for Atrial Fibrillation Patients After Pulmonary Vein Isolation
In this study, the researchers explored a new approach to manage atrial fibrillation, a disease that affects millions worldwide.
- Trial name
- relievED (NCT06283654)
- Testing
- 1-lead ECG
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Amsterdam UMC, location VUmc
Encephalopathy
Build a Decision Aid Tool to Help Emergency Intensive Care Specialists in the Context of Hypoxic Ischemic Encephalopathy
The project aims at designing a machine learning solution able to recognize characteristics signals patterns of brain damages in full term babies born within a context of Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- NewbornDS (NCT05114070)
- Testing
- Decision of hypothermia
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Conditions, Multiple, Medical Emergencies
Older Emergency Department Users and Hospitalization After an Index Visit: Results of ER2 Database
This study evaluates the recommendations of a screening tool called: ER2 (Emergency Room Evaluation and Recommendations Form).This stool is used in Emergency Department by nurses, and it supposes to measure patient risk score.
- Trial name
- NCT04017273
- Where
- Canada
- Volunteers
- 10,971 people
- Sponsor
- Jewish General Hospital
Polytrauma Patients
The Kampala Trauma Score in the Outcome of Polytrauma Patients
The goal of this observational study is to learn about the predictive value of the Kampala Trauma Score in Egypt. The main question it aims to answer is: How does the performance of the Kampala Trauma Score compare to the…
- Trial name
- NCT06699641
- Volunteers
- 110 people
- Sponsor
- Assiut University
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