Clinical trials: Emergency Departments
HIV Infections
Rapid HIV Testing for Emergency Department Patients
The purpose of this study is to test data collection options in emergency departments (EDs) and to enhance ED patient awareness of the risk of HIV infection.
- Trial name
- NCT00676481
- Testing
- HIV risk education
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Anxiety Fear, Pain
Efficacy of Mindfulness as an Intervention in the Pediatric Emergency Department
Non-pharmacological interventions including distraction techniques (ie., games, ipads, bubbles, stickers) are standard of care in reducing situation anxiety for children in the pediatric emergency department.
- Trial name
- NCT03690531
- Testing
- Take-Pause virtual reality, Passive Distraction
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Antonios Likourezos
Vaso-occlusive Crisis
Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric
Sickle cell disease (SCD) is characterized by an abnormal hemoglobin, the main protein in the red blood cell. From the first months of life, acute obstruction of the vessels of the microcirculation manifests as intense and…
- Trial name
- INVOPE (NCT06181695)
- Testing
- Sufentanil
- Volunteers
- 182 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dialysis, Trauma Related Injuries
Analysis of Emergency Department (ED) Volumes During Natural Disasters
The 'Analysis of Emergency Department Volumes during Natural Disasters' retrospective study focuses on three specified populations including dialysis patients, trauma patients, and patients poisoned by carbon monoxide.
- Conditions
- Dialysis, Trauma Related Injuries, Carbon Monoxide Poisoning
- Trial name
- NCT01059981
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic
This study investigates patients' perceptions of their doctor's or nurse's empathy during an in-person interaction with the doctor or nurse wearing personal protective equipment (PPE) compared to during a video interaction with…
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT05102656
- Testing
- Best Practice, Discussion, Questionnaire Administration
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- M.D. Anderson Cancer Center
Language Barrier
Evaluation of an E-tool Designed to Facilitate Communication Between Allophone Patients and Pediatricians in Emergency Departments.
In France, over 21 million people visit emergency departments every year, 10% of whom speak little or no French. The language barrier is a problem for patient safety and quality of care.
- Trial name
- ENTENTE (NCT06414772)
- Testing
- Use of MARTI application in addition with a classical consultation/support
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Acute Thoraco-Abdominal Emergency Lesions
Vision-Language-Based Large-Scale Model for Emergency Screening
This is a single-center, prospective, stratified 1:1 parallel-group randomized superiority diagnostic trial at The First Hospital of Jilin University.
- Trial name
- NCT07899931
- Testing
- powER vision-language large-model assisted CT reading, Conventional CT reading without AI assistance
- Where
- China
- Volunteers
- 640 people
- Sponsor
- The First Hospital of Jilin University
Trauma Injury
A Nursing Triage Protocol for Minor Orthopedic Traumata: the Effect on Flow Time, Quality of Care and Patient Satisfaction in an Emergency Department
In 2019, nearly half of all hospital contacts in Belgium took place through the emergency department, and more than a third of patients arrived after an accident or trauma.
- Trial name
- TRINU-RX (NCT05765045)
- Testing
- Nursing triage protocol
- Where
- Belgium
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Headaches Chronic
Feasibility and Effectiveness of Home-behavioral Program for Adolescents With Migraine
Chronic Migraine and Migraine without aura at high frequency are disabling conditions also in adolescence age (2% of adolescents report chronic migraine) Common pharmacological treatments are often inadequate.
- Trial name
- Be-Home-Kids (NCT04604977)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Analgesia After ED Discharge for Extremity Injuries
Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
There will be 3 randomized, double-blinded clinical trials to help determine which of commonly prescribed oral opioid combination is most effective in managing acute extremity pain after discharge from the adult emergency…
- Trial name
- NCT01402375
- Testing
- Hydrocodone (first trial), Codeine (first trial), Oxycodone (for second trial)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Montefiore Medical Center
Contraception
Impact of Combined Hormonal Contraceptives on UPA
The purpose of this research study is to determine if taking a birth control pill effects how well an emergency contraceptive pill called Ulipristal acetate (UPA) works.
- Trial name
- NCT02577601
- Testing
- Ulipristal Acetate, Levonorgestrel (LNG)/Ethinyl estradiol birth control pill
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Asthma, Acute Asthma
Budesonide Inhalation Suspension for Acute Asthma in Children
The purpose of this study is to determine whether the addition of budesonide inhalation suspension (BIS) to the standard therapy of albuterol, ipratropium bromide, and systemic corticosteroids (SCS) for moderate to severe asthma…
- Conditions
- Asthma, Acute Asthma, Reactive Airway Exacerbation
- Trial name
- NCT00393367
- Testing
- Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg, Prednisolone, prednisone, or methylprednisolone, Albuterol, ipratropium bromide
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Children's Hospital of Philadelphia
Sepsis Syndrome, Emergency Department
Can we Improve Mortality Prediction in Patients With Sepsis in the Emergency Department
This study aims to identify the prognostic role of procalcitonin (PCT), soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), the soluble form of the urokinase plasminogen activator receptor (suPAR), highly…
- Conditions
- Sepsis Syndrome, Emergency Department, Biomarker
- Trial name
- NCT06338111
- Testing
- ELISA Sepsis Biomarkers dosage
- Where
- Romania
- Volunteers
- 67 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Suicide
Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial
This study will enroll patients presenting to the emergency department with acute suicidal ideation meeting inclusion and exclusion criteria.
- Trial name
- LDK-SI (NCT01892995)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Migraine Headache
Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in the Emergency Department
Migraine headache is a frequent Emergency Department complaint. While first-line Emergency Department treatment for this condition is well-established, optimal second-line treatment options are not well-defined.
- Trial name
- NCT02492295
- Testing
- Propofol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albert Einstein Healthcare Network
Acute Pain, Opioid Use
Low-dose KETamine as an Adjunct to MOrphine for Acute Pain in the ED
The KetMo study is an investigator-initiated, randomized, parallel group, double blinded trial investigating if ketamine as an adjunct to morphine improves pain treatment in the ED.
- Trial name
- KetMo (NCT05422001)
- Testing
- low dose ketamine
- Where
- Denmark
- Volunteers
- 116 people
- Sponsor
- University of Aarhus
Old Age
End-of-Life Patient Identification Assistance in Acute GEriatric Medicine
The main objective of this project is to build a tool, adapted to the French geriatric population, that will predict the risk of death at three months after hospitalization in acute geriatric medicine.
- Trial name
- ARPEGE (NCT03549585)
- Testing
- Criteria for Screening and Triaging to Appropriate aLternative care
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Toulouse
Asthma Attack, Emergency Medicine
Asthma Attack in the Emergency Department : Reasons Of This Attendance
Objective: Identify modifiable factors that may affect asthma control and the use of emergency room to define customized interventions for the management of asthma prior to emergency room.
- Trial name
- AERO (NCT03099915)
- Testing
- completion of self-reported questionnaires
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Olivier CHASSANY
Posttraumatic Stress Disorder
Examining an Emergency Room Intervention for the Prevention of Post Traumatic Stress Disorder (PTSD)
PTSD is a common and distressing possible outcome following exposure to a traumatic event. Recent studies show that memory processes may be central to the development of the disorder, and interrupting the consolidation of…
- Trial name
- NCT01162044
- Testing
- Computer game
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hypertension
A Hypertension Emergency Department Intervention Aimed at Decreasing Disparities
Effective interventions that can address uncontrolled hypertension, particularly in underrepresented populations that use the emergency department (ED) for primary care, are critically needed.
- Trial name
- AHEAD2 (NCT03093532)
- Testing
- ED SBIRT-HTN, PACHT-c
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
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