Clinical trials: Emergency Departments
Appendicitis
EHR-based Decision Support for Pediatric Acute Abdominal Pain in Emergency Care
Although appendicitis is the most common surgical emergency in children, its diagnosis remains a challenge and thus, emergency department (ED) providers increasingly rely on computed tomography to distinguish appendicitis from…
- Trial name
- Appy-CDS (NCT02633735)
- Testing
- Appy CDS
- Where
- 2 sites in United States
- Volunteers
- 5,940 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
The Focus is to Investigate Effect of a Case Management Interventions in Frequent Visitors to Emergency Departments
A Case Management Study Targeted to Reduce Health Care Utilization for Frequent Emergency Department Visitors
The aim of the study is to determine whether a nurse-managed telephone-based case-management intervention can reduce healthcare utilization and improve self-assessed health status in frequent emergency department users.
- Trial name
- NCT01985074
- Testing
- Case-management intervention
- Where
- Sweden
- Volunteers
- 15,000 people
- Sponsor
- Health Navigator
Emergency Department Overcrowding
ED Post-Discharge Digital Follow-Up: A Communication Comparison
Emergency department overcrowding is a universal phenomenon associated with worse patient outcomes and a negative impact on healthcare teams.
- Trial name
- NCT07447674
- Testing
- Standard Telephone Follow-Up, Enhanced Digital Communication Strategy
- Volunteers
- 466 people
- Sponsor
- Hospital Israelita Albert Einstein
Cellulitis
Comparison of Intravenous Cefazolin Plus Oral Probenecid With Oral Cephalexin for the Treatment of Cellulitis
The purpose of this study is to determine whether oral cephalexin is equivalent to intravenous cefazolin plus oral probenecid for the treatment of uncomplicated skin and soft tissue infections in patients that present to the…
- Trial name
- NCT01029782
- Where
- 2 sites in Canada
- Volunteers
- 206 people
- Sponsor
- Kelowna General Hospital
HIV Infections
Two Approaches to Routine HIV Testing in a Hospital Emergency Department
This study was initially designed to compare the effectiveness of two different approaches to providing routine HIV counseling, testing, and referral services in an urban hospital emergency department setting.
- Trial name
- USHER (NCT01258582)
- Testing
- Oral HIV screening, Fingerstick HIV screening
- Where
- United States
- Volunteers
- 1,651 people
- Sponsor
- Massachusetts General Hospital
Behavioral Disorders
Descriptive Study of Emergency Room Visits From Nursing Home Residents for Behavioral Problems at the Nancy University Hospital: Place of the Advanced Practice Nurse
The demographic evolution of old age is a reality. After the age of 75, 2 out of 3 people living in institutions have neurocognitive disorders.
- Trial name
- NCT04846608
- Testing
- Observation
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Central Hospital, Nancy, France
Influenza Vaccination
PROmotion of FLU Vaccine Uptake in the Emergency Department - PROFLUVAXED
The goal of this research is to increase influenza vaccine acceptance and uptake in vulnerable populations whose primary (and often only) health care access occurs in emergency departments (ED Usual Source of Care Patients).
- Trial name
- PROFLUVAXED (NCT05836818)
- Testing
- Question (Q), Messaging (M)
- Where
- 8 sites in United States
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Asymptomatic Hypertension
Innovative Approaches to Hypertension Management in High-Risk Emergency Department Populations
This single-center, single-arm quasi-experimental study will assess the feasibility and acceptability of a community health worker (CHW)-led intervention to address social determinants of health (SDOH) among emergency department…
- Trial name
- aHTN-Manage (NCT07539597)
- Testing
- Community Health Worker engagement
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac Arrest
Epidemiology and Cost-effectiveness of Out-Of-Hospital Cardiac Arrest in Finland
Observational study of all out-of-hospital cardiac arrest during 6 months in regional areas of Helsinki University Hospital and Kuopio University Hospital from activation of EMS system until follow up to 6 months of…
- Trial name
- FINNRESUSCI (NCT01295424)
- Testing
- No intervention
- Where
- Finland
- Volunteers
- 2,600 people
- Sponsor
- Kuopio University Hospital
Intracerebral Hemorrhage (ICH), Hemorrhagic Stroke, Intracerebral
Spleen Volume Change Predicts 45-Day Mortality in Neurocritical Care: A Prospective Cohort Study
This study investigates whether changes in spleen size over 72 hours can help predict the risk of death within 45 days in patients who were admitted to the emergency department with a type of bleeding in the brain called…
- Conditions
- Intracerebral Hemorrhage (ICH), Hemorrhagic Stroke, Intracerebral, Neurocritical Care, Acute Brain Injury
- Trial name
- SCOPE (NCT07132996)
- Testing
- POCUS-based Splenic Volume Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Emergency Department Admission, Imaging Techniques
Referral Guidelines for Imaging Exams: Impact on Exam Relevance and Associated Delays
The main objective of this study is to evaluate the impact of the implementation of referral guidelines for imaging exams requested by the emergency department on exam relevance.
- Trial name
- RIU (NCT01785368)
- Testing
- Implementation of guidelines, Baseline observation
- Where
- France
- Volunteers
- 8,549 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Psychosis, Agitation
Ziprasidone vs Standard Therapy for Agitated Patients in the ED
The primary objective is to determine if ziprasidone is superior to standard therapies in the emergency department treatment of the acutely agitated patient.
- Conditions
- Psychosis, Agitation, Delirium
- Trial name
- NCT00786318
- Testing
- ziprasidone, Standard therapy
- Where
- United States
- Sponsor
- George Washington University
Ischemic Stroke, Acute
Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-D )
To compare the prognosis of patients with hyperacute ischemic stroke (arriving at the emergency department between 4.5-6 hours of symptom onset) managed in a standard stroke unit adherent to guidelines versus managed in Emergency…
- Trial name
- NCT06522282
- Testing
- Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Tiantan Hospital
Technology
Evaluation of a Novel Mobile Phone Application ( OptiBP) for Blood Pressure Monitoring
Evaluation of a novel smartphone application designed to estimate blood pressure (systolic-diastolic and mean arterial pressure) and heart rate based on collected optical signals on patient's finger treated in the emergency…
- Trial name
- NCT04121624
- Testing
- novel mobile phone application for blood pressure monitoring.
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Erasme University Hospital
Sepsis, Septic Shock
Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ
Study Title: Implementation of a Sepsis Management Protocol at Armed Forces Hospital Jazan (AFHJ). Purpose: The purpose of this quality improvement project is to determine if implementing a standardized, evidence-based "sepsis…
- Conditions
- Sepsis, Septic Shock, Systemic Inflammatory Response Syndrome (SIRS), Critical Illness
- Trial name
- NCT07460024
- Testing
- Adapted Surviving Sepsis Campaign (SSC) Protocol, Standard Clinical Care
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Urinary Tract Infections
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
The purpose of this research study is to determine if gentamicin is as effective treatment of acute uncomplicated cystitis (urinary tract infection) using aminoglycosides versus the current standards of care.
- Trial name
- NCT05702762
- Testing
- Gentamicin, Standard of Care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Musculoskeletal Pain
Emergency Department Acupuncture for Acute Musculoskeletal Pain Management
The purpose of this project is to determine the feasibility, acceptability and effectiveness of acupuncture in the Emergency Department (ED) for treating acute musculoskeletal pain.
- Trial name
- NCT04290741
- Testing
- Auricular (Battlefield) Acupuncture, Peripheral Acupuncture
- Where
- United States
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Duke University
SCD, Vaso Occlussive Crisis
Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis
Sickle cell disease (SCD) is a prevalent inherited blood disorder characterized by vaso-occlusive crises (VOCs), which lead to severe pain and complications.
- Trial name
- FLASC (NCT07188766)
- Testing
- Sodium Chloride (NaCl) 0.9 %
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 394 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Delirium
Delirium Screening of the Elderly in the Emergency Department
This study will refine and pilot test an innovative, emergency department (ED)-based intervention for delirium screening, initial management, and communication with inpatient providers, and examine the impact of this intervention…
- Trial name
- SCREEN-ED (NCT02801851)
- Testing
- SCREEN-ED
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Northeastern University
Poison;Medicinal, Extracorporeal Membrane Oxygenation
Treatment of Extracorporeal Membrane Oxygenation in Severe Poisoning
This is a prospective, multicentre clinical study to determine the value of the Extracorporeal Membrane Oxygenation in the treatment of critically ill poisoning patients and whether there are significant differences in the…
- Trial name
- NCT05762029
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
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