Clinical trials: Emergency Departments
End-Tidal Carbon Dioxide Measurement, Capnography
Comparison of Capnography and Blood Gas PaCO₂ Measurements
Capnography provides continuous, non-invasive assessment of ventilation by measuring end-tidal carbon dioxide (EtCO₂). Different capnographic technologies, including mainstream, sidestream, and microstream capnography, may…
- Trial name
- CAPNO-PaCO2 (NCT07834411)
- Testing
- Mainstream Capnography, Sidestream Capnography, Microstream Capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
HIV Pre-exposure Prophylaxis, PrEP
HIV Pre-Exposure Prophylaxis (PrEP) Linkage With Immediate Medications in the Emergency Department Study
Our primary objective is to increase HIV pre-exposure prophylaxis (PrEP) awareness and uptake among people who want, need, or would benefit from PrEP in Dallas, TX through a pilot program of immediate PrEP prescribing in the…
- Trial name
- PrEP ED (NCT07462611)
- Testing
- PrEP Uptake with Rapid Start, Pre-Exposure Prophylaxis (PrEP) Persistence
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Methicillin-Resistant Staphylococcus Aureus
Analysis of CA-MRSA Transmission: An ED Population Sampling Strategy
Given that the Emergency Department (ED) has become the entry way for large populations of patients into the health care system, a strategy of sampling MRSA isolates in ED populations and merging this information with…
- Trial name
- NCT02363166
- Testing
- Acute Abscess Group
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- University of Florida
Text Messages, Emergencies
Text Message Appointment Reminders
This project proposes administer and evaluate via a randomized controlled trail a text message-based appointment reminder system to promote attendance at clinic appointments after ED discharge.
- Trial name
- TAR (NCT01676337)
- Testing
- Text message appointment reminder
- Where
- United States
- Volunteers
- 374 people
- Sponsor
- University of Southern California
Intubation; Difficult or Failed, Airway Obstruction
Comparing iView Video Laryngoscope in the Emergency Department
The US Military is rapidly transitioning into preparing for multi-domain operations. Previous data demonstrates that the most common airway replaced in the prehospital combat setting is endotracheal intubation.
- Trial name
- NCT04907695
- Testing
- I View Video Laryngoscope https://www.intersurgical.com/content/files/108253/-1977057700
- Where
- 2 sites in United States
- Volunteers
- 168 people
- Sponsor
- Brooke Army Medical Center
Acute CHF, Acute Stroke Syndromes
PREMIUM Registry: PRognostic HEModynamIc Profiling in the AcUtely Ill EMergency Department Patient
This multinational registry (3 USA, 2 European centers) will capture in the ED continuous non invasive hemodynamic monitoring (using Nexfin finger cuff technology) of patients presenting with acute heart failure, stroke syndromes…
- Conditions
- Acute CHF, Acute Stroke Syndromes, Systemic Infections
- Trial name
- PREMIUM (NCT01208077)
- Where
- 4 sites in United States, Italy and 1 more
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acute Ischemic Stroke, Large Vessel Occlusion
Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit
This study investigates whether direct transfer to an emergency stroke unit equipped with NeuAngio-CT reduces time to endovascular reperfusion in patients with acute ischemic stroke and suspected intracranial large-vessel…
- Trial name
- NCT07670065
- Testing
- Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit, Conventional Thrombectomy
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Beijing Tiantan Hospital
Pulmonary Aspiration of Gastric Contents, Emergency Surgery
Gastric Ultrasound for Airway Management in Emergency Patients
This prospective observational cohort study evaluates the association between gastric residual content and volume, assessed by point-of-care gastric ultrasound (PoCUS), and the choice of airway management technique (Rapid…
- Conditions
- Pulmonary Aspiration of Gastric Contents, Emergency Surgery, Gastric Residual Volume, Airway Management
- Trial name
- NCT07640165
- Testing
- Preoperative Gastric Point-of-Care Ultrasound (PoCUS)
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Universitas Indonesia
Atrial Fibrillation (AF)
Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation
The goal of this observational study is to better understand the role of measuring troponin (a protein measured by a blood test) and coronary imaging in patients presenting with rapid atrial fibrillation (AF) The main questions…
- Trial name
- Mi-AF (NCT06951100)
- Testing
- CT coronary angiography
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Edinburgh
Substance Use Disorder (SUD)
Peer Support Workers Study
Many people with high-risk opioid use visit emergency departments (EDs), facing a high risk of death if they leave before completing care.
- Trial name
- NCT07030192
- Testing
- Emergency Department Peer Availability
- Where
- Canada
- Volunteers
- 3,781 people
- Sponsor
- University of British Columbia
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation
Emergency Care, Telemedicine
Telemedicine-Based Emergency Physician Assessment Prior to ED Entry: A Randomized Controlled Trial
Background: Emergency department (ED) overcrowding is a growing challenge worldwide and is associated with prolonged length of stay (LOS), reduced patient satisfaction, and increased burden on healthcare systems.
- Conditions
- Emergency Care, Telemedicine, Emergency Department Crowding
- Trial name
- NCT07546071
- Testing
- Telemedicine-Based Remote Physician Assessment
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Surgical Procedures, Operative
Determining Universal Processes Related to Best Outcome in Emergency Gastrointestinal Surgery: an International Evaluation
A multicentre, international evaluation of emergency abdominal surgery to establish surgical outcomes and identify common, modifiable best practice processes.
- Trial name
- GlobalSurg-1 (NCT02179112)
- Testing
- Emergency Abdominal Surgery
- Where
- United Kingdom
- Volunteers
- 10,745 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Orofacial Pain, Orofacial Edema
Evaluation of Out of Hours Dental Emergency Treatments
For 12 years, the odontology service of the Pitié-Salpêtrière hospital group (GHPS) has been responsible for day and night dental emergency care.
- Conditions
- Orofacial Pain, Orofacial Edema, Dental Trauma, Oral Infection
- Trial name
- URGDENT-NW (NCT04352881)
- Testing
- Questionary patient
- Where
- France
- Volunteers
- 369 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hemodialysis Catheter Complication, Catheter Thrombosis
Hemodialysis Catheter Complications in the Emergency Department Versus Hemodialysis Unit
This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency…
- Conditions
- Hemodialysis Catheter Complication, Catheter Thrombosis, Catheter-Related Infections, Hemodialysis Vascular Access
- Trial name
- NCT07645365
- Where
- Turkey (Türkiye)
- Volunteers
- 398 people
- Sponsor
- Antalya Health Sciences University
Supraventricular Tachycardia
Modified Valsalva Maneuver: A Realist Evaluation
Cardiac arrhythmia, specifically paroxysmal supraventricular tachycardia (SVT), accounts for a substantial proportion of emergency medical services resources utilization.
- Trial name
- NCT05466227
- Testing
- Implementation of Modified Valsalva maneuvre
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Ziekenhuis Oost-Limburg
Cardiac Arrest
Effectiveness of Pediatric Intubation
We hypothesized that the Venner videolaryngoscope (A.P. Advance™) is beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of the Venner videolaryngoscope (A.P.
- Trial name
- PETI (NCT02289651)
- Testing
- Venner, Miller
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Emergencies, Diagnostic Imaging
Abdominal Plain X-ray in the Emergency Departement
There are only few recognized indications for the realization of plain abdominal X-rays in the emergency departement. The objective of this study is to explore the reasons for abdominal plain X-rays prescription in the Emergency…
- Conditions
- Emergencies, Diagnostic Imaging, Abdomen, Acute
- Trial name
- NCT02980081
- Testing
- abdominal plain x-ray
- Where
- Switzerland
- Volunteers
- 1,997 people
- Sponsor
- University Hospital, Geneva
Pain
Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.
Intranasal hydromorphone has been shown to be effective in reducing acute pain in adults. It has not been previously studied in children, but may be a viable option for effectively and safely reducing pain in children by…
- Trial name
- NCT02437669
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Columbia University
Procedural Sedation and Analgesia
Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department
The purpose of this study is to compare the effectiveness of the co-administration of intravenous ketamine and propofol to intravenous ketamine as a single agent for procedural sedation in the pediatric emergency department.
- Trial name
- NCT01387139
- Testing
- Ketamine, Ketamine Co-administered with Propofol
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of Colorado, Denver
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