Clinical trials: Emergency Departments
Pain, Acute
Analgesic Efficacy of Orally Administered VTS-K for Pain Management
A combination of ketamine and aspirin for the treatment of acute MSK pain in the ED would confer multimodal analgesia, with the contributions of aspirin and ketamine to an opioid sparing effect.
- Trial name
- NCT04702555
- Testing
- VTS-K
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Antonios Likourezos
Alcohol Drinking
Implementing Mobile Technology for Unhealthy Alcohol Use
Scalable approaches are needed to support patients identified in the emergency department as unhealthy alcohol users and text messaging intervention approaches are a promising solution.
- Trial name
- NCT05350878
- Testing
- Implementation Intervention
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- UConn Health
Wounds and Injuries, Acute Coagulopathy
Pre-hospital Anti-fibrinolytics for Traumatic Coagulopathy and Haemorrhage (The PATCH Study)
The purpose of this research is to determine whether giving severely injured adults a drug called tranexamic acid (TXA) as soon as possible after injury will improve their chances of survival and their level of recovery at six…
- Trial name
- PATCH (NCT02187120)
- Testing
- Tranexamic Acid
- Where
- 33 sites in Australia, New Zealand
- Volunteers
- 1,310 people
- Sponsor
- Monash University
Traumatic Pneumothorax and Hemothorax
Emergency Small vs Large Tube Thoracostomy in Chest Trauma Patients.
To compare between small sized tube thoracostomy and large sized tube thoracostomy regarding the need for another chest tube for the fear of obstruction (in hemomothorax) or ineffective drainage (in hemothorax, pneumothorax or…
- Trial name
- NCT04863989
- Testing
- tube thoracostomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Catheterization, Peripheral, Phlebotomy
VeinViewer for Peripheral IV Placement in Children With Difficult Intravenous (IV) Access
Hypothesis: The first attempt success rate for peripheral IV insertion for children with difficult IV access (difficult IV access [DIVA] score ≥ 4) by nurses using the VeinViewer guided technique is better than conventional…
- Trial name
- NCT00357799
- Testing
- VeinViewer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Children's Hospital and Health System Foundation, Wisconsin
Community-Acquired Pneumonia (CAP), Pneumonia
PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
In North America, up to 5% of preschoolers develop community-acquired pneumonia (CAP) every year. Pneumonia is the second-leading reason for paediatric hospitalization in both Canada and the US; approximately 20% of children…
- Trial name
- PIONEERS (NCT07099976)
- Testing
- The novel care pathway intervention, Usual Care Alone
- Where
- 6 sites in Canada
- Volunteers
- 698 people
- Sponsor
- Jeffrey Pernica
Myocardial Infarction
Accelerated Rule Out of Myocardial Infarction
Every year > 50.000 people in Denmark are hospitalized with a suspected acute myocardial infarction (AMI). The majority has other explanations of their chest discomfort and most are discharged again without any initiation of…
- Trial name
- AROMI (NCT02666326)
- Testing
- Accelerated, combined biomarker rule-out strategy for MI
- Where
- 3 sites in Denmark
- Volunteers
- 4,516 people
- Sponsor
- Aarhus University Hospital Skejby
Multiple Organ Failure, End Stage Cardiac Failure
Timing of Acute Palliative Care Consultation in Critically Ill Patients
A prospective randomized controlled trial studying the ordering of palliative care consultations in the emergency department (Ig) versus later palliative care consultations in the hospital--ICU or hospital ward(Cg).
- Conditions
- Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5
- Trial name
- NCT02858778
- Testing
- Early order of palliative care consultation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
Acute Coronary Syndrome
Enoxaparin Versus Unfractionated Heparin in Subjects Who Present to the Emergency Department With Acute Coronary Syndrome (RESCUE)
The purpose of this study is to determine the efficacy and safety of enoxaparin compared to unfractionated heparin (UFH) for patients diagnosed with Acute Coronary Syndrome (ACS) in the emergency department (ED).
- Trial name
- NCT00077818
- Testing
- Enoxaparin sodium
- Sponsor
- Sanofi
Musculoskeletal Diseases or Conditions, Emergency Department
Advanced Practice Physiotherapy Care in Emergency Departments
Overcrowding in emergency departments (ED) is a major concern worldwide. Recent reports show that Canada has among the longest ED waiting times and limited access to care has been associated with poorer outcomes for many…
- Conditions
- Musculoskeletal Diseases or Conditions, Emergency Department, Physiotherapy
- Trial name
- NCT05545917
- Testing
- Experimental: APP care, Control - Usual physician care
- Volunteers
- 744 people
- Sponsor
- Maisonneuve-Rosemont Hospital
General Anesthesia
Gastric Ultrasound in Paediatric Anaesthesia
Anesthesia for emergency surgery is a situation at risk of pulmonary aspiration of gastric contents. It has been previously reported that bedside two-dimensional ultrasonography can be a useful tool for anesthesiologists to…
- Trial name
- ECHOGASTRO (NCT02584348)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Peritonitis, Primary Closure
Outcome of Primary vs Delayed Primary Closure of Laparotomy in Dirty Abdominal Wounds
This randomized controlled trial is designed to evaluate and compare two different wound management strategies-primary closure (PC) and delayed primary closure (DPC)-in patients undergoing emergency laparotomy for peritonitis The…
- Conditions
- Peritonitis, Primary Closure, Delayed Primary Closure
- Trial name
- NCT07531576
- Testing
- Delayed Primary Laparotomy wound Closure, Primary Abdominal Closure
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Ayub Teaching Hospital
Stroke
Comparative Evaluation of Stroke Triage Algorithms for Emergency Medical Dispatchers
This study will compare the diagnostic accuracy of Card 28 stroke protocol to Card 28 and Cincinnati Stroke Scale, when used by emergency medical dispatchers to interrogate a 911 call suggestive of stroke.
- Trial name
- MeDS (NCT01202318)
- Where
- United States
- Sponsor
- University of California, San Francisco
Appendicitis
European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Background Acute appendicitis is an extremely common surgical emergency. Traditionally, appendicitis has been managed surgically.
- Trial name
- SnapAppy (NCT04365491)
- Where
- Ireland
- Volunteers
- 4,000 people
- Sponsor
- Gary Alan Bass, MD PhD
Cancer, Frailty
Association of ICU Admission Time, Age Stratification, and Clinical Frailty Scale With 30-Day Mortality in Geriatric Oncology Patients
Geriatric oncology patients frequently require intensive care admission and are at increased risk of adverse outcomes due to advanced age, frailty, and critical illness.
- Conditions
- Cancer, Frailty, Mortality
- Trial name
- NCT07825090
- Testing
- Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Chest Pain
Longitudinal Strain in Addition to Visual Assessment of Wall Motion for Ruling in Ischemia in the Emergency Room
To assess the utility of technician-based analysis of echocardiograms with longitudinal strain for ruling-in ischemic chest pain in the emergency room, compared to emergency room (ER) physician opinion and expert…
- Trial name
- NCT01111643
- Testing
- Echocardiogram
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Hillel Yaffe Medical Center
Hypertension, Stroke
REACH OUT: to Reduce High Blood Pressure in the Emergency Department
One of the most powerful predictors of stroke is hypertension, with estimates of approximately 33% of adults in the United States experiencing this condition.
- Trial name
- NCT02301455
- Testing
- Text messaging
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Michigan
Headache
The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine
Investigators are comparing Ketamine to prochlorperazinecompazine for benign headaches in the ED. Subjects will be randomized into 1 of 2 groups.
- Trial name
- Check (NCT02735343)
- Testing
- Compazine, Ketamine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mike O'Callaghan Military Hospital
Dizziness, Vertigo
Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo
This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.
- Trial name
- NCT06010550
- Testing
- Magnetic resonance imaging
- Volunteers
- 600 people
- Sponsor
- Chiayi Christian Hospital
Pain Management
Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Oxycodone and Hydrocodone are the most commonly used oral opioid analgesics in the emergency department and in outpatient settings.
- Trial name
- NCT03088826
- Testing
- Morphine Sulfate, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
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