Clinical trials: Emergency Medical Services
Patient Discharge, Emergency Care
Trial of Emergency Department Discharge With Enhanced Transitions of Care Compared to Usual Care
This is a randomized controlled trial to assess the relative effectiveness of providing Enhanced Transitions of Care (ETOC) to improve patient outcomes after discharge from the Emergency Department (ED).
- Trial name
- ETOC (NCT02533856)
- Testing
- ETOC
- Volunteers
- 316 people
- Sponsor
- Thomas Jefferson University
Flu
Alere i FluA*B Biologic Test Relocated in Emergency Service for Flu Diagnosis
It appears that the heavyness of flu pathology, the diagnosis limits and the validity of it was well studied in the last years.However, the economical impact and the organisation benefit in emergency service is not yet evaluated…
- Trial name
- NCT03293979
- Testing
- Test A i Flu A&B implemented in emergency service
- Where
- France
- Volunteers
- 301 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pneumonia, Diaphragm; Movement
Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department.
The goal of this Prospective interventional multicenter diagnostic study is to investigate the use of diaphragmatic ultrasound (DE) as a diagnostic tool in an adult emergency department for patients in acute respiratory distress.
- Conditions
- Pneumonia, Diaphragm; Movement, Diaphragmatic Ultrasound, Emergency Medical Services
- Trial name
- EchoDiaph (NCT06650137)
- Testing
- diaphragmatic ultrasound
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Fatigue
SleepTrackTXT Feasibility and Pilot Study
Aim 1: To determine if real-time assessments of perceived sleepiness and fatigue using text-messaging impacts an emergency medicine clinician's Attitudes, Perceived Norms, Self-Efficacy, Alertness Habits, Perceived Importance of…
- Trial name
- SleepTrackTXT (NCT02063737)
- Testing
- Text-message assessments only, Text-message interventions for high level fatigue
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stroke
Direct Transfer to an Endovascular Center Compared to Transfer to the Closest Stroke Center in Acute Stroke Patients With Suspected Large Vessel Occlusion
To evaluate the hypothesis that direct transfer to an Endovascular Stroke Center, compared to transfer to the closest Local Stroke Center, offers a better outcome in the distribution of the modified Rankin Scale scores at 90 days…
- Trial name
- RACECAT (NCT02795962)
- Testing
- Direct transfer to an Endovascular Center
- Where
- 12 sites in Spain
- Volunteers
- 1,401 people
- Sponsor
- Fundacio Ictus Malaltia Vascular
Musculoskeletal Pain
Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)
This study compares the efficacy of five oral analgesics: 5 mg oxycodone + 325 mg acetaminophen, 5 mg hydrocodone + 300 mg acetaminophen, 30 mg codeine + 300 mg acetaminophen, 400 mg ibuprofen + 1000 mg acetaminophen, and 800 mg…
- Trial name
- NCT03173456
- Testing
- oxycodone/APAP, hydrocodone/APAP, codeine/APAP
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Albert Einstein College of Medicine
Posttraumatic Stress Disorder, Cannabis Use Disorder
Mitigating PTSD-CUD After Sexual Assault
683,000 women are sexually assaulted annually in the United States, half of whom develop chronic posttraumatic stress disorder (PTSD) and thus have markedly increased risk for cannabis use disorder (CUD).
- Trial name
- RISE-C (NCT05989841)
- Testing
- RISE Guide, Relaxation Control
- Where
- 6 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of Nevada, Las Vegas
Analgesia, Prehospital
Quality of Telemedically Guided Prehospital Analgesia
The purpose of this retrospective study is to analyze quality and adverse events of analgesia by telemedically supported paramedics in comparison to conventional treatment by on-scene emergency medical service (EMS) physicians in…
- Conditions
- Analgesia, Prehospital, Telemedicine, Ambulance
- Trial name
- NCT02928705
- Testing
- physician operated telemedical prehospital analgesia, prehospital analgesia by on-scene EMS physicians
- Where
- Germany
- Volunteers
- 381 people
- Sponsor
- RWTH Aachen University
Status Epilepticus
Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant Medications
The goal of this non-inferiority trial is to determine which type of routine care is the best for paramedics to stop someone from seizing.
- Trial name
- RAMPART (NCT00809146)
- Testing
- Intramuscular route of active treatment, Intravenous route of active treatment
- Where
- 17 sites in United States
- Volunteers
- 1,023 people
- Sponsor
- Robert Silbergleit
Sepsis
Implementation of a qSOFA Score in the Emergency Department
The Quick-SOFA score (qSOFA), identifies septic patients with a mortality risk higher than 10%. In our study all adult patients coming to the emergency for suspected infection are screened according to the qSOFA score on arrival.
- Trial name
- qSOFA2 (NCT04568746)
- Testing
- emergency vital room, box
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Outcome From Traumatic Cardiac Arrest
This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest.
- Trial name
- NCT05294575
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Artificial Intelligence, Machine Learning
Appropriate Use of Blood Cultures in the Emergency Department Through Machine Learning
The goal of this clinical trial is to study whether the use of our blood culture prediction tool is non-inferior to current practice and if it can improve certain outcomes in all adult patients presenting to the emergency…
- Conditions
- Artificial Intelligence, Machine Learning, Microbiology, Emergency Service, Hospital
- Trial name
- ABC (NCT06163781)
- Testing
- Blood culture prediction tool
- Where
- Netherlands
- Volunteers
- 7,584 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Acute Bronchial Obstruction, Asthma
Efficacy of Formoterol vs Ipatropioum Bromide Plus Fenoterol in Children (5-<12 Years) With Acute Bronchial Obstruction
To determine efficacy and tolerability of inhaled Formoterol vs nebulized Ipatropioum Bromide plus Fenoterol in cumulative sequential doses in asthmatic children (5-<12 years) with acute bronchial obstruction attending emergency…
- Trial name
- NCT00460577
- Testing
- Formoterol fumerate, fenoterol/ipratropium bromide
- Where
- 2 sites in Venezuela
- Volunteers
- 60 people
- Sponsor
- Novartis
Cardiopulmonary Resuscitation
Pilot Study Comparing Ventilation Modes During CPR With Mechanical Compression Device.
Comparison of three ventilation modes (volume controlled, BIPAP and CPAP) during cardiopulmonary re-suscitation with a mechanical compression device in the emergency room.
- Trial name
- COVME (NCT03347175)
- Testing
- Volume controlled ventilation, Pressure controlled ventilation, CPAP mode
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technical University of Munich
Sepsis
Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
The aim of this research study is to compare two different fluids (Human Albumin Solution (HAS) and Balanced Crystalloid that are given via a drip to patients with severe infection (sepsis).
- Trial name
- ABC Sepsis (NCT04540094)
- Testing
- Human albumin, Balanced crystalloid solution
- Where
- 15 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Edinburgh
Acute Critical Illnesses in Emergency Settings, Process Optimization of Early Warning &Amp; Assessment for At-risk Emergency Patients
Early Warning Score Combined With Bedside Assessments: Accelerating Emergency Care To Improve Prognosis
Brief Summary This study, sponsored by the National Natural Science Foundation of China and conducted at the Emergency Department (ED) of Jiangnan University Affiliated Hospital, aims to optimize emergency care for critically ill…
- Trial name
- EWS-BA (NCT07249151)
- Testing
- Optimized ED Bedside Nursing Protocol
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Jun Liu
Out-of-Hospital Cardiac Arrest
Smartphone Video-assisted Advanced Life Support of Patients With Out-of-hospital Cardiac Arrest by EMS Under Physician Direction
Direct medical control using video conferencing capabilities of smartphones has never been conducted in out-of-hospital cardiac arrest patients.
- Trial name
- SWALS (NCT03041350)
- Testing
- Smartphone video-assisted ALS(advanced life support)
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Urinary Calculi, Emergency Service, Hospital
Analysis the Relationship Between the Abdomen CT and Outcomes in Acute Urinary Stone Patients
This is an observational study based on retrospectively collected data of ureter stone patients between 2011 and 2014. Aim of study is to determine radiologic findings of non-contrast abdominal computerized tomography as…
- Trial name
- NCT02983409
- Testing
- Pstone
- Volunteers
- 862 people
- Sponsor
- Konkuk University Medical Center
Recognition of Thrombectomy Candidate
Implementation of Finnish Prehospital Stroke Scale to Emergency Medical Services
The investigators have developed a simple prehospital stroke scale (FPSS), containing 5 dichotomized items to recognize both large and small artery thrombi of the brain.
- Trial name
- NCT03520335
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Cardiac Arrest, Needle Stick
Needle Stick Injuries in Emergency Medical Service Practice
During the pandemic era, medical personnel should wear full protective suits. However, they limit the performance of medical procedures. One of the main questions is whether to use double gloves.
- Conditions
- Cardiac Arrest, Needle Stick, Injuries, Glowe
- Trial name
- NCT04363788
- Testing
- double gloves
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Lazarski University