Clinical trials: Emergency Patients
Moderate-to-severe Acute Pain
Open-Label Safety and Efficacy of the Sufentanil Sublingual Tablet 30 mcg for Acute Pain
To evaluate the safety and efficacy of sufentanil tablet (ST) 30 mcg in the management of moderate-to-severe acute pain in patients in an emergency room (ER) setting.
- Trial name
- NCT02447848
- Testing
- sufentanil sublingual 30 mcg tablet
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Talphera, Inc
Dehydration
Ultrasound of the Inferior Vena Cava (IVC) and Dehydration Status in Pediatric Emergency Patients
Objective: Although approximately 9% of patients presenting to a Pediatric Emergency Department (ED) are dehydrated, there is no reliable method to measure objectively the degree of intravascular dehydration.
- Trial name
- NCT00267644
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Hypertension
Monitoring Blood Pressure at Home
The overall goal of this project is to determine if measuring blood pressure at home and staying in contact with a team of pharmacists and physicians to manage your blood pressure is feasible.
- Trial name
- NCT06247111
- Testing
- Remote Blood Pressure Monitoring + Telehealth, Usual care
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Alabama at Birmingham
Dementia
Program of Intensive Support in Emergency Departments for Care Partners of Cognitively Impaired Patients
Dementia is a common problem for older patients presenting to emergency departments and for the family caregivers who often lack support, understanding, and skills to manage the problems related to the need for emergency…
- Trial name
- POISED (NCT03325608)
- Testing
- POISED Care
- Where
- United States
- Volunteers
- 889 people
- Sponsor
- NYU Langone Health
Advanced Cancer, Hematologic Malignancy
Fatigue in Emergency Center Patients
1. To describe fatigue severity and its related symptom clusters in cancer patients who are seeking emergency care for fever, pain, shortness of breath, or cancer therapy-related gastrointestinal toxicities. 2.
- Conditions
- Advanced Cancer, Hematologic Malignancy, Fatigue
- Trial name
- NCT00504985
- Testing
- Surveys
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- M.D. Anderson Cancer Center
Smoking Cessation
An Intervention to Reduce Second Hand Smoke Exposure Among Pediatric Emergency Patients
This study will test the efficacy of a cessation intervention for caregivers in a large, inner-city Pediatric Emergency Department.
- Trial name
- NCT02531594
- Testing
- SBIRT, HHC
- Where
- United States
- Volunteers
- 770 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hemorrhage
This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding
The primary objective is to demonstrate reversal of the anticoagulant effect of dabigatran in patients treated with dabigatran etexilate who have uncontrolled or life-threatening bleeding requiring urgent intervention, and in…
- Trial name
- NCT03343704
- Testing
- Idarucizumab
- Where
- 13 sites in China
- Volunteers
- 19 people
- Sponsor
- Boehringer Ingelheim
Contraception Behavior
A Trial of an Adolescent Male Sexual Health Intervention
Early unintended fatherhood and rates of sexually transmitted infections remain national concerns, disproportionately affecting minority, underserved adolescent males, many of whom frequently use emergency departments (EDs) for…
- Trial name
- DrEric (NCT04969289)
- Testing
- Dr. Eric Digital Health Intervention
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Columbia University
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hypertension, High Blood Pressure
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single…
- Conditions
- Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction
- Trial name
- NCT00689819
- Testing
- Exercise, Weight Loss, Low Sodium Diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Pain
Association Between Body Size and Response to Hydromorphone in ED
Pain is the most common complaint for patients presenting to the emergency department (ED). Inadequate pain relief is also a common problem in ED.
- Trial name
- NCT01675778
- Testing
- Hydromorphone
- Where
- 2 sites in United States
- Volunteers
- 174 people
- Sponsor
- Albert Einstein College of Medicine
Airway Control, Anesthesia
Ketamine Versus Etomidate for Rapid Sequence Intubation
The purpose of this study is to compare the effectiveness and safety of ketamine and etomidate during rapid sequence intubation (RSI).
- Conditions
- Airway Control, Anesthesia, Intubation, Complication
- Trial name
- NCT01823328
- Testing
- Ketamine, Etomidate
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- Hennepin Healthcare Research Institute
Alcohol Dependence, Alcohol Use Disorder
Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users
Our primary aim is to assess the feasibility of initiating treatment in the ED with extended-release naltrexone (XR-NTX) plus care management (CM) vs.
- Trial name
- NCT02445339
- Testing
- XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Bronchiolitis
Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
The purpose of this study is to assess whether children with moderate to severe bronchiolitis treated with standard racemic epinephrine therapy via 70:30 helium-oxygen (heliox) driven nebulization will have improvements in…
- Trial name
- NCT00116584
- Testing
- heliox, oxygen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Acute Pain
Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Patients treated with protocolized pain management (1 mg of IV hydromorphone followed by an additional 1 mg IV hydromorphone if the patient wants more) will have better pain relief and no more adverse events than patients…
- Trial name
- NCT00627367
- Testing
- Hydromorphone, Nonprotocolized
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
External Causes of Morbidity and Mortality
Comparative Analysis of APACHE II and P-POSSUM
To compare APACHE II and P-POSSUM scoring system in emergency laparotomy.
- Trial name
- NCT02471612
- Where
- India
- Volunteers
- 159 people
- Sponsor
- Tata Main Hospital
Orofacial Swelling
Efficacy of Buffered Lidocaine in Patients With Facial Swelling
The purpose of this study is to determine the clinical efficacy of a buffered 4% lidocaine solution for incision and drainage. Ninety patients will be examined clinically to determine a diagnosis of cellulitis or fluctuance.
- Trial name
- NCT01981772
- Testing
- 4% lidocaine with 1:100,000 epinephrine, 4% buffered lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Ohio State University
ED Patients With Chronic Medical Illnesses
An Emergency Department-To-Home Intervention to Improve Quality of Life and Reduce Hospital Use
The purpose of this study is to determine if assigning older, chronically ill patients a healthcare coach after they leave the Emergency Department (ED) improves their quality of life and reduces the need for hospital-based care.
- Trial name
- NCT02079987
- Testing
- ED-to-home care transition intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 1,101 people
- Sponsor
- University of Florida
Diabetes Mellitus
Harnessing mHealth and Social Support to Improve Diabetes Related Health Behavior for Inner-city Patients
In this study, an existing mobile health intervention to improve diabetes self-management will be combined with a social support module and tested for feasibility.
- Trial name
- TExTMEDFANS (NCT01945996)
- Testing
- TExT MED, FANS
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Southern California
Cancer, Diarrhea
CASAD for Severe Diarrhea in the Emergency Department
The goal of this clinical research study is to learn if calcium alumina-silicate (CASAD) can help to stop your diarrhea. Researchers also want to know if this drug can help decrease the duration of your diarrhea.
- Trial name
- NCT02018653
- Testing
- Calcium Alumina-Silicate (CASAD), Questionnaire
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- M.D. Anderson Cancer Center