Clinical trials: Emotion Dysfunction
Severe Eosinophilic Asthma, Psychological Distress
Severe Asthma, MepolizumaB and Affect: SAMBA Study
This is a real-life pragmatic non-randomised study to explore the impact of mepolizumab on the emotional and affective outcomes of patients with severe eosinophilic asthma and their partners.
- Conditions
- Severe Eosinophilic Asthma, Psychological Distress, Anxiety, Depression
- Trial name
- SAMBA (NCT04680611)
- Testing
- no study intervention. Patients receive standard clinical care
- Where
- 6 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Stroke, Fatigue
Emotional and Cognitive Determinants of Post-stroke Fatigue
Fatigue is a prevalent, prolonged and partly disabling symptom following cerebral stroke. The health services has little knowledge of fatigue, both in terms of what characterizes those affected, and with regard to how fatigue can…
- Conditions
- Stroke, Fatigue, Post-Stroke Fatigue, Neuropsychology
- Trial name
- NCT03639259
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- University Hospital of North Norway
Pain, Fatigue
Fatigue in Chronic Pain - Cognition, Emotional Aspects, Biomarkers, and Neuronal Correlates
The investigators will examine mental/cognitive as well as cognitive functions (executive functions, attention functions, processing speed, learning and memory) in 200 patients with chronic pain and 36 healthy controls.
- Conditions
- Pain, Fatigue, Cognitive Impairment
- Trial name
- NCT05452915
- Testing
- Neuropsychological (NPA), Imaging, Inflammatory biomarkers
- Where
- 3 sites in Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Coronary Artery Disease, Coronary Artery Ectasia
Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck…
- Conditions
- Coronary Artery Disease, Coronary Artery Ectasia, Slow-Flow Phenomenon, Endothelial Dysfunction
- Trial name
- STRAIN-TIMI (NCT02831153)
- Testing
- coronary angiography
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Ertan YETKIN
Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood
Brain Changes in Children and Adolescents With Behavioral Problems
Purpose: This study will examine brain activity in children age 10-18 with disruptive behavior problems, including conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD)…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood, Conduct Disorder
- Trial name
- NCT00104039
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cognitive Impairment
Gene Expression, Meditative Movement, and Emotional Distress (GME)
Study Title: Gene Expression, Meditative Movement and Emotional Distress (GME) Background and Objectives: Breast cancer survivors (BCS) often report decrements in cognitive functioning.
- Trial name
- GME (NCT04213872)
- Testing
- Meditative Movement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Arizona State University
Personality Disorder, Borderline, Personality Trait
Bridging Affect Consciousness, Mentalization and Trauma- Exploring an Integrative Treatment Approach for Personality Disorder (PD).
Study background: Specialized Group Outpatient Clinic within specialist mental health services, tailoring two year group treatment programmes for severe Avoidant PD (AvPD) and Borderline PD (BPD) with Affect Consciousness (AC)…
- Conditions
- Personality Disorder, Borderline, Personality Trait, Personality Disorder, Personality Type
- Trial name
- NCT06983002
- Testing
- Experimental group: AC-group therapy intervention., Control group 1: Body Awareness Group., Control group 2: Art Psychotherapy group.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Helse Stavanger HF
Mild Cognitive Impairment, Depressive Symptoms
Homebound Elderly People Psychotherapeutic Intervention
This study aims to develop, implement, and assess the feasibility, acceptability, and preliminary efficacy of a 10-week structured and individualized cognitive-emotional intervention program for homebound older adults with Mild…
- Conditions
- Mild Cognitive Impairment, Depressive Symptoms, Anxiety State
- Trial name
- HEPPI (NCT04967378)
- Testing
- HEPPI
- Where
- Portugal
- Volunteers
- 51 people
- Sponsor
- University of Coimbra
Substance Use Disorders, PTSD
A Mobile App for Peer-led Seeking Safety
Peer support is historically prominent for substance use disorder (SUD), such as the world-wide model of Alcoholics Anonymous and other 12-step groups.
- Conditions
- Substance Use Disorders, PTSD, Trauma, Emotional Dysfunction
- Trial name
- NCT03846115
- Testing
- Peer-Led Seeking Safety app, Control app
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Treatment Innovations
Stroke, Cognitive Impairment
Cognitive and Emotional Impairment After Stroke
Cognitive and emotional symptoms are often seen in the acute phase of a stroke. The prevalence of such symptoms later and the mechanisms explaining the symptoms are not fully known.
- Conditions
- Stroke, Cognitive Impairment, Vascular Dementia
- Trial name
- NCT00506818
- Testing
- Multifactorial vascular-risk-factor-intervention
- Where
- Norway
- Volunteers
- 250 people
- Sponsor
- Sykehuset Asker og Baerum
Multiple Sclerosis, Cognitive Deficits
Effects of Cognitive Behavioural Therapy and Exercise on Stress and Cognitive Deficits in Multiple Sclerosis
High levels of psychological stress have been reported by 90% of patients with MS experiencing disease exacerbation, and approximately 39% of those with more stable disease course.
- Conditions
- Multiple Sclerosis, Cognitive Deficits, Stress, Psychological
- Trial name
- NCT01763983
- Testing
- Cognitive Behavioural Therapy, Aerobic Exercise
- Where
- Canada
- Volunteers
- 173 people
- Sponsor
- Sunnybrook Health Sciences Centre
Distress, Emotional, Emotional Dysfunction
Brief Interventions for Coping with Distress
This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training…
- Conditions
- Distress, Emotional, Emotional Dysfunction, Anxiety, Depression
- Trial name
- NCT05779761
- Testing
- Online, Self-Directed Attention Skills Training with Coaching Support, Online, Self-Directed Attention & Reflective Thought Skills Training with Coaching Support, Online, Self-Directed Health & Wellness Education Training with Coaching Support
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Teachers College, Columbia University
Autism Spectrum Disorder, Asthma
Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)
FACT 4 Child is a follow up study of mothers who participated in the Folic Acid Clinical Trial (NCT01355159) and their children at 4-6 years of age to determine the effect of high dose folic acid supplementation on social…
- Conditions
- Autism Spectrum Disorder, Asthma, Executive Dysfunction, Emotional Problem
- Trial name
- NCT03269110
- Testing
- SRS 2, CBCL, BRIEF-P
- Where
- 58 sites in Australia, Canada and 2 more
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Obesity, Cognitive Disorder
Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery
This research investigates obesity and associated psychiatric symptoms and disorders in a wide range of perspectives, to demonstrate the effects of obesity on the brain.
- Trial name
- NCT03528044
- Testing
- Bariatric surgery
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Koç University
Self-injurious Thoughts and Behaviours, Borderline Personality Disorder
Development and Initial Testing of a Couple-Based Intervention to Optimize Suicide and Self-Injury Treatment: COMPASS (Connecting, Overcoming, and Moving Past Suicide and Self-Injury)
Self-injurious thoughts and behaviors (SITBs), including suicide, thinking about suicide, and self-injury without intent to die, are major public health crises, with variably effective, and sometimes long and expensive…
- Trial name
- COMPASS (NCT04737252)
- Testing
- Sage (formerly known as COMPASS)
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- York University
Psychological Stress, Mental Fatigue
A Multi-Dimensional Comparative Study of Exercise Psychological Experience Under AI Fitness Companion and Human Coach Paradigms
This study conducted a comparative analysis of subjective exercise experiences between an AI-based fitness companion and traditional human coaching among 98 university students participating in a standardized 20-minute functional…
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- NCT07690553
- Testing
- AI-Based Companion, Human-Coached
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Emotional Dysfunction
Day Hospital Treatment of Emotional Dysregulation
Objective: The goal of this proposed research project is a quantitative analysis of a day hospital program designed to treat persons with emotional dysregulation.
- Trial name
- NCT04280614
- Testing
- Dialectical behaviour therapy (DBT)
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Manitoba
Multiple Sclerosis
Emotions in Multiple Sclerosis
Through this study, a group composed of multiple sclerosis patients will be compared to a healthy volunteers group to determine if the positive emotions recognitions is preserved in the first group.
- Trial name
- RECODE (NCT04804787)
- Testing
- Carrying out a tests and questionnaires battery
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Lille Catholic University
Mild Cognitive Impairment (MCI), Memory Disorders, Age Related
Music for the Mind Study
The goal of this pilot clinical trial is to learn if older adults with mild cognitive impairment (MCI) find two music programs equally acceptable.
- Conditions
- Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
- Trial name
- M4M (NCT06866327)
- Testing
- Piano lessons, Music Lessons
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester