Clinical trials: Emotional Disorder
Mood Disorders
Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)
New treatments to help to reduce the emotional dysregulation of mood disorders are critically needed. This is a study of an emotional dysregulation psychotherapy treatment in which participants will learn skills to help to…
- Trial name
- BE-SMART (NCT03183388)
- Testing
- BE-SMART
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Yale University
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Benzodiazepine Dependence, Anxiety Disorders
Anxiety Lowering and Deprescribing Through Emotion Regulation
The goal of this clinical trial is to test ALDER (Anxiety Lowering and Deprescribing through Emotion Regulation), an online self-guided positive emotion intervention, in patients over the age of 65 who are candidates for…
- Conditions
- Benzodiazepine Dependence, Anxiety Disorders, Sleep Disturbance
- Trial name
- ALDER (NCT06359314)
- Testing
- ALDER
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Fetal Alcohol Spectrum Disorders
A Study of Parent and Child Emotions in Fetal Alcohol Spectrum Disorder (FASD)
The purpose of this study is to learn about the emotion regulation skills of children with fetal alcohol spectrum disorders (FASD) and different strategies that may improve these skills.
- Trial name
- NCT03524664
- Testing
- Tuning In to kids intervention
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Rochester
Child Behavior, Attention Deficit and Disruptive Behavior Disorders
Tantrum Tamers 2.0: The Role of Emotion
This study aims to better understand how to best help parents of young children with problem behavior. Problem behaviors vary between and within children, but can include inattention/hyperactivity, tantrums, and/or noncompliance.
- Conditions
- Child Behavior, Attention Deficit and Disruptive Behavior Disorders, Problem Behavior
- Trial name
- NCT03597789
- Testing
- Helping the Noncompliant Child (HNC)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Parkinson Disease
Effects of Deep Brain Stimulation on Motor, Mood, and Cognitive Symptoms in Parkinson's Disease
The purpose of this trial is to study the mood and cognitive effects of deep brain stimulation in Parkinson's disease.
- Trial name
- NCT00360009
- Testing
- DBS of the STN, DBS of the GPI
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Florida
Depression, Anhedonia
Anhedonia, Development, and Emotions: Phenotyping and Therapeutics
The goal of the ADEPT Study is to understand anhedonia in young people and how it changes based on treatments targeting the brain circuit underlying it.
- Trial name
- ADEPT (NCT05487885)
- Testing
- Continuous theta burst stimulation (cTBS), Positive Affect Training, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Erika Forbes
Intermittent Explosive Disorder, Childhood Aggression
Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder
Children with explosive aggression are often rejected by their peers, placed in special classroom, and contribute to family discord. When psychotherapy and family therapy is unsuccessful, medications are often used.
- Conditions
- Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
- Trial name
- NCT02048241
- Testing
- Parent Management Training, Intuniv
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- New York State Psychiatric Institute
Anxiety, Depression
Neuromodulation Enhanced Cognitive Restructuring: A Proof of Concept Study
Psychological treatments are effective, but take a long time and can be burdensome. Therefore, avenues to optimize behavioral treatments are needed.
- Conditions
- Anxiety, Depression, Personality Disorders, Trauma and Stress-related Disorders
- Trial name
- NCT02573246
- Testing
- Cognitive Restructuring, rTMS
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Duke University
Depression, Anxiety
Mobile Mental Health Apps for Suicide Prevention
Access to mental health care by essential workers and the unemployed during the COVID19 pandemic has been challenging. Usual access to mental health care is limited by social distancing, and for many now unemployed due to…
- Conditions
- Depression, Anxiety, Emotional Regulation
- Trial name
- NCT04536935
- Testing
- Mobile Mental Health App - 1, Mobile Mental Health App - 2, Mobile Mental Health App - 3
- Where
- United States
- Volunteers
- 838 people
- Sponsor
- University of Washington
Traumatic Brain Injury
Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)
The purpose of this pilot study is to investigate the relationship between attention and emotional function post-Traumatic Brain Injury (TBI) in an effort to better understand the cognitive mechanisms of emotional processing in…
- Trial name
- NCT01681589
- Testing
- Transcranial Direct Current Stimulator (TDCS), Control Group, Healthy Control Group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Thyroid Cancer, Thyroid Nodule
The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer
118 adults with benign thyroid nodules who were seen at a UW Health clinic for a fine needle biopsy and do not need surgery will be enrolled and can expect to be on study for a one-time visit of up to 60 minutes.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Benign Thyroid Nodule
- Trial name
- NCT05132478
- Testing
- Emotionally Supportive Video, Standard Video
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Wisconsin, Madison
Breast Cancer Female, Depressive Symptoms
The Role of Emotional Processing in Improving the Quality of Life of Breast Cancer Patients
The purpose of this study is to examine two mechanistic changes: emotion processing (awareness, expression and acceptance) and cholinergic anti-inflammatory processes (HRV and cytokine expression) through which an Art Therapy…
- Conditions
- Breast Cancer Female, Depressive Symptoms, Fatigue, Pain
- Trial name
- REPAT (NCT03377816)
- Testing
- Art Therapy
- Where
- Israel
- Volunteers
- 318 people
- Sponsor
- University of Haifa
Depression
Emotional and Cognitive Control in Late-Onset Depression
This study may help identify how abnormalities in brain systems that control the ability to ignore irrelevant information may contribute to the development of depression in older adults.
- Trial name
- NCT01728194
- Testing
- Escitalopram, Magnetic Resonance Imaging
- Where
- 2 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Major Depression
Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine
The purpose of this study is to find out what parts of the brain have increased or decreased activity when people are depressed and how antidepressant medicine changes this activity in depressed patients.
- Trial name
- NCT00532480
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Concussion, mTBI
Neurofeedback Impact on Veterans With mTBI
This study will evaluate neurofeedback (NFB) training as a low risk, non-invasive, effective treatment for Veterans diagnosed with mild traumatic brain injury (mTBI) and experiencing chronic post-concussive symptoms (PCSs).
- Conditions
- Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache
- Trial name
- NFBVETmTBI (NCT04195685)
- Testing
- Neurofeedback (NFB)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Emotional Disturbances, Depression
Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
The overall purpose of this application is to evaluate the efficacy of an intervention designed to decrease health disparities in pregnant, emotionally distressed, minority women.
- Conditions
- Emotional Disturbances, Depression, Pregnancy Late, Post-Partum Depression
- Trial name
- A-RCT (NCT03416010)
- Testing
- COPE-P
- Where
- 3 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Ohio State University
ADHD
Amiloride Hydrochloride as an Effective Treatment for ADHD
The investigators are proposing to test a medication derived from our prior studies of the gene SLC9A9. This one gene makes NHE proteins that control how we learn and remember items, which is impaired in ADHD and may cause an…
- Trial name
- NCT01733680
- Testing
- amiloride, Behavioral
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- State University of New York - Upstate Medical University
Attention Deficit Hyperactivity Disorder
Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD
The aim of this study is to examine the mechanisms by which stimulant medications reduce symptoms in patients with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01415440
- Testing
- Lisdexamfetamine
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute