Clinical trials: Emotional Disorder
Post Traumatic Stress Disorders
Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?
Service Dogs are trained to assist people with disabilities to accomplish tasks which permit the individual to be more functional in their home and social environment.
- Trial name
- SDPTSD (NCT02039843)
- Testing
- Emotional Support Dogs, Service Dogs
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety and Fear
Memory and Fear Study (Fear of Memory Loss Study)
This study is a randomized control study to determine the impact of a tailored, web-based mindfulness program to reduce anxiety and increase the quality of life in older adults experiencing dementia-related fears, relative to a…
- Trial name
- NCT04821960
- Testing
- Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Aging, Mild Cognitive Impairment
Internet-based Conversational Engagement Clinical Trial
The study aims to randomize 320 (160 Caucasian, 160 African American) socially isolated adults 75+ years old (50:50 split between those with normal cognition and mild cognitive impairment (MCI)) recruited from the community to…
- Trial name
- I-CONECT (NCT02871921)
- Testing
- Conversational Engagement
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment, Neuropsychiatric Syndrome
CogT BEEM Study (a tDCS Study)
Co-existing neuropsychiatric symptoms (NPS) in patients with mild cognitive impairment (MCI), especially those worsening over time, are associated with more rapid cognitive and functional decline and a greater risk of Alzheimer's…
- Trial name
- NCT04099524
- Testing
- tDCS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Physical Inactivity, Overweight or Obesity
eMOTION Formative Study
The eMOTION Study is a two-part ORBIT model phase 1 trial. The first part, called the Formative Study, will assess acceptability and feasibility of a novel physical activity intervention in adults at increased risk for cancer due…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06125964
- Testing
- Intensity-Based Goals, Affect-Based Goals, TYPE/CONTEXT Enhancement
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Depression, Anxiety
Mobile Mental Health Apps for Suicide Prevention
Access to mental health care by essential workers and the unemployed during the COVID19 pandemic has been challenging. Usual access to mental health care is limited by social distancing, and for many now unemployed due to…
- Conditions
- Depression, Anxiety, Emotional Regulation
- Trial name
- NCT04536935
- Testing
- Mobile Mental Health App - 1, Mobile Mental Health App - 2, Mobile Mental Health App - 3
- Where
- United States
- Volunteers
- 838 people
- Sponsor
- University of Washington
Cognitive Impairment
Gene Expression, Meditative Movement, and Emotional Distress (GME)
Study Title: Gene Expression, Meditative Movement and Emotional Distress (GME) Background and Objectives: Breast cancer survivors (BCS) often report decrements in cognitive functioning.
- Trial name
- GME (NCT04213872)
- Testing
- Meditative Movement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Arizona State University
Major Depressive Disorder, Anxiety
Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms
The purpose of this study is to investigate the efficacy and safety of flexibly dosed adjunctive brexpiprazole treatment in subjects with major depressive disorder and anxiety symptoms, who are experiencing an inadequate…
- Trial name
- NCT02013531
- Testing
- Brexpiprazole
- Where
- 21 sites in United States
- Volunteers
- 37 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Drug Addiction
Cannabidiol and Emotional Stimuli
The purpose of this research is to examine the effect of cannabidiol (CBD), a cannabinoid compound found in marijuana, on responses to emotional stimuli.
- Trial name
- CAS (NCT02902081)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Non-verbal Learning Disorder, Autism Spectrum Disorder
Natural Treatments for the Management of Emotional Dysregulation in Youth With Non-verbal Learning Disability (NVLD) and/or Autism Spectrum Disorders (ASD)
This study consists of a 6-week, open-label, randomized clinical trial study to compare efficacy and tolerability of the natural treatments omega-3 fatty acids, inositol, and N-acetylcysteine (NAC) in the treatment of mood…
- Conditions
- Non-verbal Learning Disorder, Autism Spectrum Disorder, Autism
- Trial name
- NCT03757585
- Testing
- Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Reducing Challenging Behaviors in Children With Autism Through Digital Health
School-based behavioral approaches to managing challenging behaviors in children with ASD are limited by three key factors: 1) children with ASD often have difficulties communicating their emotions; 2) it is challenging to…
- Trial name
- NCT05277194
- Testing
- KeepCalm app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Alzheimer Disease
SAGE-LEAF: Reducing Burden in Alzheimer's Disease Caregivers Through Positive Emotion Regulation and Virtual Support
The goal of the proposed study, is to adapt a positive emotion intervention for Alzheimer's Disease (AD) caregivers into a self-guided online format that incorporates social connection components and adaptive system feedback…
- Trial name
- SAGE-LEAF (NCT05562583)
- Testing
- SAGE LEAF
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- BrightOutcome
Thyroid Cancer, Thyroid Nodule
The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer
118 adults with benign thyroid nodules who were seen at a UW Health clinic for a fine needle biopsy and do not need surgery will be enrolled and can expect to be on study for a one-time visit of up to 60 minutes.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Benign Thyroid Nodule
- Trial name
- NCT05132478
- Testing
- Emotionally Supportive Video, Standard Video
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Wisconsin, Madison
Multiple Sclerosis, Relapsing, Remitting
Evaluation of Emotional Disorders During Treatment by Interferon Beta in Relapsing-remitting Multiple Sclerosis Patients
This study is planned to evaluate emotional disorders during treatment by interferon (IFN) beta in relapsing remitting multiple sclerosis (RRMS) subjects.
- Trial name
- SEPTIME (NCT01201343)
- Testing
- Interferon beta-1a
- Volunteers
- 79 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Anorexia Nervosa, Atypical Anorexia Nervosa
Parent Emotion Coaching for Anorexia Nervosa
Family based treatment (FBT) is the evidence based treatment for pediatric anorexia nervosa (AN), but 50% of adolescents do not respond and the consequences for non-response are dire (e.g., 11.5% mortality rate).
- Trial name
- NCT04421989
- Testing
- Emotion Coaching, Support Group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression, Anxiety
Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor(SPEAC) for Adults With Emotional Distress (Phase 2)
Approximately 200 Participants with mild-to-moderate, untreated depression and/or anxiety will be randomly assigned (by chance, like flipping a coin) to 1 of 3 study groups: Lumen Coached Problem-Solving Treatment (PST) (n=100)…
- Trial name
- SPEAC (NCT05603923)
- Testing
- Lumen Coached PST Intervention., Human Coached PST Intervention., Optional (delayed) Lumen Coached PST (Waitlist control).
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Illinois Chicago
Overweight and Obesity, Eating Behavior
An ACT-Based Physician-Delivered Weight Loss Intervention
The purpose of the present study was to conduct a pilot RCT to test the feasibility of a physician-delivered ACT-based intervention for emotional eaters with overweight/obesity against standard care at a network of weight loss…
- Trial name
- NCT03611829
- Testing
- ACT Intervention, Standard Care
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- McGill University
Obsessive Compulsive Disorder
Sertraline Pediatric Registry for the Evaluation of Safety (SPRITES)
To evaluate the long-term impact of treatment with sertraline on aspects of cognitive, emotional and physical development and pubertal maturation in pediatric subjects ages 6 to 16 years (inclusive) with a diagnosis of anxiety…
- Trial name
- SPRITES (NCT01302080)
- Testing
- sertraline, psychotherapy
- Where
- 44 sites in United States
- Volunteers
- 941 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Anxiety Disorder, Depressive Disorder
Feasibility of a Culturally Adapted Emotional-Behavioral Prevention Program for American Indian Children
American Indians (AI) are at greater risk for anxiety and depression early in life. This is concerning given the potential negative effects of these conditions across the lifespan (substance use, suicide).
- Trial name
- NCT05371665
- Testing
- Culturally Adapted Cognitive-Behavioral Prevention and Early Intervention (PEI) Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Montana State University