Clinical trials: End Stage Chronic Renal Failure
Venous Thromboembolic Disease, Kidney Failure, Chronic
Anticoagulation Strategies for Acute Venous Thromboembolism in Patients With End-Stage Renal Disease Using USRDS Data
Patients with end stage renal disease (ESRD) are at significantly increased risk of thrombosis and bleeding relative to those with normal renal function which makes anticoagulation particularly challenging.
- Trial name
- NCT04818151
- Testing
- Warfarin, Apixaban
- Where
- United States
- Volunteers
- 14,914 people
- Sponsor
- Johns Hopkins University
Anorexia, Thalassemia
Clinical Diagnosis of Teenagers Admitted to Pediatric Departments
This study intends to analyze the clinical characteristics of teenagers admitted to pediatric wards due to organic illness and non organic diagnosis, including patients suffering from chronic diseases and comorbidity.
- Conditions
- Anorexia, Thalassemia, Sickle Cell Anemia, Chronic Renal Failure
- Trial name
- NCT00735540
- Testing
- Observational
- Where
- Israel
- Volunteers
- 1,389 people
- Sponsor
- HaEmek Medical Center, Israel
End-Stage Renal Disease
Morbidity, Mortality, Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania
Background: In the last 2 decades, Tanzania made great improvements in the renal replacement therapy infrastructure and services.
- Trial name
- NCT03988491
- Where
- Tanzania
- Volunteers
- 10,000 people
- Sponsor
- Benjamin Mkapa Hospital
End Stage Renal Disease
Effect of Icodextrin Solution on Preservation of Residual Renal Function in Patients on Peritoneal Dialysis
Peritoneal dialysis (PD) is an established dialysis modality in patients with end stage renal disease (ESRD). However, there is growing awareness of the deleterious effect of high glucose content in PD solutions on the peritoneal…
- Trial name
- NCT01170858
- Testing
- Icodextrin PD solution, glucose solutions
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
End Stage Renal Disease, Living Donor Kidney Transplantation
Social Networks and Renal Education: Promoting Transplantation
There are significant and persistent disparities in access to kidney transplantation and as a result most patients with end stage renal disease receive hemodialysis (HD).
- Conditions
- End Stage Renal Disease, Living Donor Kidney Transplantation, Renal Dialysis
- Trial name
- SNARE (NCT03536858)
- Testing
- COACH (Communicating about Choices in Transplantation)
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Temple University
Dyspnea, Chronic Renal Failure
POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients
Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.
- Trial name
- NCT05729035
- Testing
- POCUS
- Volunteers
- 100 people
- Sponsor
- Randa Ahmed Sarhan
End-stage Renal Disease
Pharmacokinetics and Dialyzability of Dapagliflozin in Dialysis Patients
Sodium-glucose co-transporter 2 inhibitors (Sglt2i) attenuate the incidence of cardiovascular events in individuals with preserved or mildly reduced kidney function.
- Trial name
- DARE-ESKD 1 (NCT05343078)
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Brazil
- Volunteers
- 5 people
- Sponsor
- University of Campinas, Brazil
Anemia, Chronic Kidney Diseases
Effect of rEPO in FGF23 in ESRD Patients
Objective: To evaluate the effects of recombinant Erythropoietin (rEPO) in plasma levels of Fibroblast Growth Factor 23 (FGF23) in End-Stage Renal Disease (ESRD) patients in hemodialysis.
- Trial name
- NCT03803514
- Testing
- Recombinant EPO
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Kidney Disease, Chronic, End Stage Renal Disease
The Effect of Exercise on Dialysis Patients' Survival
The purpose of this study is to check if patients' exercise during their dialysis sessions can prevent their early deaths.
- Conditions
- Kidney Disease, Chronic, End Stage Renal Disease, Hemodialysis
- Trial name
- NCT04898608
- Testing
- Intradialytic Exercise
- Where
- 2 sites in Iran
- Volunteers
- 74 people
- Sponsor
- Pardis Specialized Wellness Institute
Cancer, Chronic Renal Failure
Identification of Palliative Care Needs and Prognostic Factors of Survival in Tailoring Appropriate Interventions in Advanced Oncological, Renal and Pulmonary Diseases
This is a prospective observational study done on 3 patient populations (cancer, chronic pulmonary and renal disease). All patients will be treated and monitored according to the local clinical practice.
- Conditions
- Cancer, Chronic Renal Failure, Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT06909968
- Testing
- palliative care
- Where
- 5 sites in Italy
- Volunteers
- 178 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Staphylococcal Infections, Chronic Kidney Failure
Evaluation of a Third and Fourth Dose of StaphVAX® in Adults With End-Stage Renal Disease
This study is a continued evaluation of the immune response to StaphVAX , a Staphylococcus aureus type 5 and 8 capsular polysaccharide conjugate vaccine, in end-stage renal disease patients, by giving a 3rd and 4th dose to a…
- Trial name
- SHIELD-2 (NCT00130260)
- Testing
- Staph aureus types 5 and 8 conjugate vaccine
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Nabi Biopharmaceuticals
End-Stage Renal Disease
Study on the Safety and Efficacy of a Time-of-Day-Based Individualized Tacrolimus Dosing Regimen in Kidney Transplant Recipients
The goal of this clinical trial is to evaluate whether chronopharmacokinetic model-guided individualized unequal twice-daily tacrolimus dosing improves renal allograft function and reduces acute rejection in stable kidney…
- Trial name
- NCT07877103
- Testing
- Chronotherapy-based individualized low-morning high-evening tacrolimus dosing, conventional dosing regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
End Stage Renal Disease
Study in End Stage Renal Disease (ESRD) Patients on Hemodialysis Comparing the Theranova Dialyzer to Hemodiafiltration
In China, the estimated prevalence of patients with ESRD receiving PD or maintenance HD increased from 51.7 per million population (pmp) at the end of 2007 to 79.1 pmp at the end of 2008.
- Trial name
- NCT03547336
- Testing
- Theranova 400 Dialyzer, FX800 Dialyzer
- Where
- 8 sites in China
- Volunteers
- 212 people
- Sponsor
- Vantive Health LLC
Hemodialysis Complication
Exercise Therapy on Rheological Functions of Erythrocyte in Hemodialysis
To improve aerobic capacity, muscular function, and health-related quality of life in patients with end-stage renal disease (ESRD), regular exercise is recommended.
- Trial name
- NCT06575634
- Testing
- Supervised exercise training
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Kidney Failure, Chronic
Efficacy and Safety of Fosrenol in Treating Elevated Serum Phosphate Levels in Adults With End Stage Renal Disease
The purpose of this study is to test how well lanthanum carbonate reduces the pre-dialysis level of serum phosphorus in subjects undergoing dialysis due to end stage renal disease and to determine the patient and physician's…
- Trial name
- NCT00160121
- Testing
- Lanthanum carbonate
- Volunteers
- 2,500 people
- Sponsor
- Shire
Chronic Renal Failure Requiring Hemodialysis
A Phase 3, Long-Term Safety Study of Intravenous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME - Anemia Management With Epoetin
The purpose of the study is to determine the long-term safety in treatment-emergent adverse events (TEAEs) of intravenous (IV) administration of Epoetin Hospira for maintenance of target hemoglobin (Hgb) levels in patients…
- Trial name
- AiME - 03 (NCT01628107)
- Testing
- Epoetin Hospira
- Where
- 110 sites in United States, Puerto Rico
- Volunteers
- 406 people
- Sponsor
- Pfizer
End Stage Renal Disease
Oral Intradialytic Amino Acid Supplementation to Vitalize End-stage Kidney Disease Patients on Hemodialysis
The study will test and compare the efficacy of a single essential amino acid valine with a combination of essential amino acids (EAA) supplement on fatigue, frailty, and cognitive function in end-stage kidney disease (ESKD)…
- Trial name
- OASIS (NCT05705414)
- Testing
- Valine, EEA
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Multiple Organ Failure, End Stage Cardiac Failure
Timing of Acute Palliative Care Consultation in Critically Ill Patients
A prospective randomized controlled trial studying the ordering of palliative care consultations in the emergency department (Ig) versus later palliative care consultations in the hospital--ICU or hospital ward(Cg).
- Conditions
- Multiple Organ Failure, End Stage Cardiac Failure, End Stage Chronic Obstructive Airways Disease, Chronic Kidney Disease Stage 5
- Trial name
- NCT02858778
- Testing
- Early order of palliative care consultation
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wayne State University
End-stage Renal Failure, Kidney Graft Rejection
Reference Group Trial for The ONE Study
To investigate the progression of the immunological response in living-donor kidney transplant recipients treated with a standard immunosuppressive regimen.
- Trial name
- NCT01656135
- Testing
- Blood drawing for immune monitoring and questionnaires
- Where
- 8 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- University of Regensburg
Kidney Failure, Chronic, End-Stage Renal Disease
Comparison of Nocturnal Hemodialysis (NHD) and Short Daily Hemodialysis (DHD) With the NxStage® System One™
The purpose of this study is to determine whether or not nocturnal hemodialysis is equivalent to short daily hemodialysis on a per treatment basis, using the NxStage System One in the home setting.
- Trial name
- NCT00667511
- Testing
- NxStage System One
- Where
- 9 sites in United States
- Volunteers
- 58 people
- Sponsor
- NxStage Medical
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