Clinical trials: End Stage Chronic Renal Failure
End-stage Renal Disease
Improving Patient-clinician Communication About End-of-life Care
The specific aims are: 1. to evaluate the feasibility and acceptability of PC-ACP among African American patients with End-stage Renal Disease and their surrogates and 2.
- Trial name
- NCT00374010
- Testing
- Patient-Centered Advance Care Planning
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Kidney Failure, Chronic
The Correlation Between Gut Microbiome/Metabolite and End Stage Renal Disease (ESRD)
The purpose of this study is to investigate the differences of gut Microbiome/Metabolite between ESRD patients and healthy subjects.
- Trial name
- NCT03010696
- Testing
- No interventions, questionnaire, collect specimen
- Where
- 4 sites in China
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- China Agricultural University
End-stage Renal Disease (ESRD)
Rheological Functions of Erythrocyte in ESRD
End-stage renal disease (ESRD) disrupts erythrocyte deformability due to osmotic imbalances, oxidative stress, and uremic toxins, leading to impaired microcirculation and oxygen transport.
- Trial name
- NCT06868888
- Testing
- Blood collection, Cardiopulmonary exercise testing (CPET)
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
End Stage Kidney Disease, Chronic Kidney Diseases
The WavelinQ™ Arterio-Venous Endovascular Fistula: A Global, Post-Market Investigation
This is a global, multi-center, prospective, post-market, confirmatory, interventional, non-randomized, single-arm clinical investigation evaluating arteriovenous fistula (AVF) creation by means of the WavelinQ™ EndoAVF System in…
- Conditions
- End Stage Kidney Disease, Chronic Kidney Diseases, Kidney Failure, Kidney Insufficiency
- Trial name
- WAVE-Global (NCT04626427)
- Testing
- WavelinQ™ EndoAVF System
- Where
- 3 sites in Belgium, Greece and 1 more
- Volunteers
- 21 people
- Sponsor
- C. R. Bard
End Stage Renal Disease, Chronic Kidney Disease
More Frequent Dialysis (>3 Treatments Per Week)
The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week…
- Trial name
- MFD (NCT00575497)
- Testing
- More frequent hemodialysis, Conventional Hemodialysis
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Satellite Healthcare
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease, Kidney Failure
C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
The use of C1INH (Berinert) in patients receiving deceased donor kidney transplants with high risk for delayed graft function (DGF) may show significant improvement in outcomes post transplant compared with patients that do not…
- Conditions
- End Stage Renal Disease, Kidney Failure, Delayed Graft Function, Ischemic Reperfusion Injury
- Trial name
- C1INHDGF (NCT02134314)
- Testing
- C1 Esterase Inhibitor
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Cedars-Sinai Medical Center
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
End-stage Renal Disease
The Effect of Fructose on Blood Fats in Dialysis Patients and Healthy Volunteers
This study will evaluate how a common dietary sugar (fructose) raises blood fats (triglycerides). We will determine whether the production of fat from fructose is higher in dialysis patients compared to healthy volunteers.
- Trial name
- NCT00234156
- Testing
- oral fructose and high fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Chronic Renal Failure
Serum Uremic Toxins and Histological Findings of the Blood Vessels in Dialysis Patients
Patients treated by chronic renal replacement therapy are exposed to cardiovascular problems and suffer from an accelerated and sever atherosclerosis.
- Trial name
- NCT00412139
- Where
- North Macedonia
- Volunteers
- 100 people
- Sponsor
- University of Skopje
Anemia, Chronic Kidney Disease
Safety, PD & PK of Multiple Doses of Peginesatide for Anemia in Chronic Kidney Disease Patients
The purpose of this study was to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple subcutaneous injections of peginesatide in participants with chronic kidney disease (CKD) not on dialysis who had…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure
- Trial name
- NCT00228436
- Testing
- peginesatide
- Where
- 13 sites in Poland, United Kingdom
- Volunteers
- 139 people
- Sponsor
- Affymax
Hyperphosphatemia, End Stage Renal Disease
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Effects of Ferric Citrate in Subjects With End Stage Renal Disease
The purpose of the study is to determine the effect and optimum dose and evaluate the safety of ferric citrate, administered three times daily (TID) immediately after meals for a total daily dose of 4 or 6 grams for 56 days, on…
- Conditions
- Hyperphosphatemia, End Stage Renal Disease, ESRD
- Trial name
- NCT01503736
- Testing
- ferric citrate
- Where
- 5 sites in Taiwan
- Volunteers
- 183 people
- Sponsor
- Panion & BF Biotech Inc.
Hypotension, End Stage Renal Disease
Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients
MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension
- Conditions
- Hypotension, End Stage Renal Disease, Intra Dialytic Hypotension
- Trial name
- NCT00448071
- Testing
- MTR107
- Where
- 2 sites in Israel
- Volunteers
- 12 people
- Sponsor
- Wolfson Medical Center
Physical Activity, End Stage Kidney Disease
The "Step4Life" Randomized Control Trial in Hemodialysis
Persons with end-stage kidney disease (ESKD) have very low physical activity, and among ESKD patients, the level of inactivity is strongly associated with morbidity and mortality.
- Conditions
- Physical Activity, End Stage Kidney Disease, Hemodialysis
- Trial name
- NCT05241171
- Testing
- Fitbit
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Diego
Multimorbidity - End-stage Kidney Disease
Molecular and Clinical Response to a Single Bout of Aerobic Exercise in a Multimorbid Population: a Study From the Consortium on Precision EXercise in Aging
The combination of data from different origins (biological, health, patient-related) has the potential to improve care for the elderly.
- Trial name
- CPExA (NCT05404698)
- Testing
- Aerobic exercise, Control
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- Université de Sherbrooke
Chronic Kidney Disease
The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients
A single blind, six week dietary intervention will be conducted in order to evaluate the impact of fiber fortified foods on blood urea nitrogen, kidney function and quality of life in patients presenting with a moderate to severe…
- Trial name
- NCT01842087
- Testing
- Control Food, Fiber Fortified Food
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
End-Stage Renal Disease
Vitamin D3 Supplementation in Dialysis Patients
Vitamin D deficiency is highly prevalent among dialysis patients, and has been associated with cardiovascular risk factors such as increased aortic pulse wave velocity, blood pressure, inflammation, and brain natriuretic peptide.
- Trial name
- NCT01312714
- Testing
- Cholecalciferol
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Regional Hospital Holstebro
Renal Impairment, End-stage Kidney Disease
A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of AZD4144 in Participants With Severe Renal Impairment, End-stage Kidney Disease, and in Healthy Participants
A study to investigate the pharmacokinetics, safety, and tolerability of AZD4144 in participants with severe renal impairment, end-stage kidney disease, and in healthy participants.
- Conditions
- Renal Impairment, End-stage Kidney Disease, Healthy Participants
- Trial name
- NCT06693765
- Testing
- AZD4144
- Where
- 2 sites in Bulgaria, Romania
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
End Stage Renal Disease, Inflammation
Influence of the Vitamine E Coated Dialyzer on Inflammation and Anemia
Evaluation of the effect of a vitamin E coated high flux polysulfone dialyzer on the inflammatory state of patients' end stage renal disease and its clinical benefits in terms of anemia Objectives : To assess the benefits of a…
- Trial name
- EVIA (NCT03218865)
- Testing
- VIE high flux dialyzer, Leoceed H high flux dialyzer
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hemotech
Chronic Renal Failure, Anemia
Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
The purpose of this study is to evaluate the safety and efficacy of multiple intravenous doses of pegol-Sihematide in participants with chronic kidney disease (CKD) who are on dialysis.
- Conditions
- Chronic Renal Failure, Anemia, Dialysis
- Trial name
- NCT02586402
- Testing
- pegol-Sihematide, Epoetin Alfa
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.