Clinical trials: End Stage Liver DIsease
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
Improving Clinician Communication Skills (ICCS)
This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians.
- Conditions
- Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure
- Trial name
- ICCS (NCT00687349)
- Testing
- Training Program Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,086 people
- Sponsor
- University of Washington
Hepatitis B, Hepatitis B, Chronic
Assessment of Hepatitis B Virus Intra-host Population and Host-specific Immune Marker Diversity
In this project proposal, the investigators will investigate the genetic alterations of Hepatitis B Virus (HBV) strains circulating in Belgian patients who developed end stage liver disease.
- Conditions
- Hepatitis B, Hepatitis B, Chronic, End Stage Liver Disease, Carcinoma, Hepatocellular
- Trial name
- NCT02148562
- Where
- Belgium
- Volunteers
- 274 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
End Stage Liver Disease
Transoesophageal Echocardiography in Liver Transplantation
Severe hypotension during reperfusion in liver transplantation is a frequent adverse event. Rare data exist so far about pathophysiology of this phenomenon.
- Trial name
- NCT00547924
- Testing
- Transoesophageal echocardiography
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University of Zurich
End Stage Liver Disease
Cardiopulmonary Exercise Testing in Cirrhotic Patients: a Pilot Study
Optimizing patient survival and organ utility is a constant struggle for the liver transplant community. Despite rigorous cardiovascular evaluation before liver transplantation cardiovascular events are one of the leading causes…
- Trial name
- NCT01658982
- Testing
- cardiopulmonary exercise testing
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Liver Disease, Liver Neoplasms
Orthotopic Liver Transplantation Using a Living Donor
The purpose of this study is to: determine the safety of donor right hepatic lobectomy as a procedure to provide a liver graft for living donor liver transplantation.
- Trial name
- NCT00152607
- Testing
- donor right hepatic lobectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Cirrhosis, End Stage Liver Disease
Mechanism and the Effect of Midodrine on Portal Pressures in Patients With Cirrhosis
Ascites is a frequent complication of patients with portal hypertension. As portal hypertension progresses, a percentage of these patients develop refractory ascites.
- Conditions
- Cirrhosis, End Stage Liver Disease, Ascites, Hypotension
- Trial name
- NCT01331785
- Testing
- Midodrine
- Where
- United States
- Sponsor
- The Cleveland Clinic
End Stage Liver DIsease
Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease
A phase I trial to study the safety of mobilization of stem cells with G-CSF and Mozobil in patients with chronic liver disease.
- Trial name
- NCT01711073
- Testing
- Mobilization with G-CSF and Mozobil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Proteonomix, Inc.
End-stage Liver Disease
Conditioning With Volatile Anesthetics in Liver Transplantation
The gap between the number of candidates for orthotopic liver transplantation and the availability of suitable liver grafts has led to a rise in deaths on most waiting lists.
- Trial name
- NCT00913276
- Testing
- Propofol, Sevoflurane
- Where
- Switzerland
- Volunteers
- 98 people
- Sponsor
- University of Zurich
Liver Cirrhosis, End Stage Liver Disease
Safety and Efficacy of Human Autologous Peripheral Blood Stem Cells for Treatment of HBV-related Liver Cirrhosis
HBV related Liver disease is a common medical problem in China. An estimated 7.18% of the Chinese (about 93 million) is infected with hepatitis B, and most of the HBV- related hepatitis can developed into liver cirrhosis.
- Trial name
- NCT01728688
- Testing
- PBSC transplantation, conventional treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Air Force Military Medical University, China
Liver Cirrhosis, End Stage Liver Disease
Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis
HBV related Liver disease is a common medical problem in China. An estimated 7.18% of the Chinese (about 93 million) is infected with hepatitis B, and most of the HBV- related hepatitis can developed into liver cirrhosis.
- Trial name
- NCT01728727
- Testing
- UC-MSC transplantation, conventional treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Air Force Military Medical University, China
Liver Cirrhosis, End Stage Liver Disease
Safety and Efficacy of Human Bone Marrow Stem Cells for Treatment of HBV-related Liver Cirrhosis
HBV related Liver disease is a common medical problem in China. An estimated 7.18% of the Chinese (about 93 million) is infected with hepatitis B, and most of the HBV- related hepatitis can developed into liver cirrhosis.
- Trial name
- NCT01724697
- Testing
- BMSC transplantation, conventional treatment & antivrial treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Air Force Military Medical University, China
End-stage Liver Disease
Prospective Trial Comparing Conventional Versus Piggyback Method in Venous Drainage of the Transplanted Liver
METHODS: Patients were submitted to conventional (n=15) or piggyback (n=17) liver transplantation (LTx). Free hepatic vein pressure (FHVP) and the central venous pressure (CVP) measurements were performed after graft reperfusion.
- Trial name
- LTx-outflow (NCT01707810)
- Testing
- Piggyback method, conventional method
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
Portal Hypertension
The Effect of Probiotics (VSL) on Portal Hypertension
The investigators will address the hypothesis that portal hypertension is mediated in part by bacterial or endotoxin translocation and the production of inflammatory mediators (tumor necrosis factor-α (TNFα), etc.).
- Trial name
- NCT01032941
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alberta
End Stage Liver Disease, Hepatic Encephalopathy
Prediction of Mortality in Patients Waiting for Liver Transplantation Through Brain Magnetic Resonance Imaging
The purpose of this study is to determine whether hepatic encephalopathy, measured through magnetic resonance imaging, electroencephalogram and neuropsychological evaluation adds prognostic information to patients who are waiting…
- Trial name
- NCT01434056
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- Hospital Israelita Albert Einstein
End Stage Liver Disease
Intra-hepatic Artery Bone Marrow Derived Stem Cells Infusion for the Treatment of Advanced Liver Cirrhosis
Liver disease is a common medical problem in Saudi Arabia. Early studies indicated that around 10% of the Saudi population is either infected with hepatitis B or C.
- Trial name
- NCT01412593
- Testing
- Stem cell transplant
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Saud University
Cirrhosis, End Stage Liver Disease
Screening for Liver Cancer With CT vs. Ultrasound in Patients With Advanced Liver Disease
The purpose of this study is to determine whether ultrasound or CT scanning is more effective at detecting early liver cancer in patients with advanced liver disease.
- Conditions
- Cirrhosis, End Stage Liver Disease, Hepatitis C
- Trial name
- NCT01350167
- Testing
- Screening
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
End Stage Liver Disease
End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)
The purpose of this research study is to see how effective bioelectric impedance analysis (BIA) is in determining body composition (the amount of fat versus muscle in the body) and nutritional status in patients with End Stage…
- Trial name
- NCT00374582
- Testing
- Bodystat Quadscan 4000, bodystat quadscan 400
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
End Stage Liver Disease, Living Donor
Effect of Intermittent Hepatic Inflow Occlusion During Donor Hepatectomy In Living Donor Liver Transplantation
Intermittent hepatic inflow occlusion (IHIO), also called Pringle maneuver, is a safe and effective procedure for major hepatectomy in patients with liver disease.
- Trial name
- NCT01171742
- Testing
- Intermittent hepatic inflow occlusion (IHIO)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Liver Transplantation
Hemodynamic Measurements During Liver Transplantation
The purpose of the study is to determine if the less invasive monitors are as reliable for measuring heart function in patients undergoing liver transplantation as the more invasive pulmonary artery.
- Trial name
- OLT (NCT00682110)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Washington University School of Medicine
Liver Failure, Cirrhosis
Improvement of Liver Function in Liver Cirrhosis Patients After Autologous Mesenchymal Stem Cell Injection:a Phase I-II Clinical Trial
The methods for separation of mesenchymal stem cell were established in 2001. These cells can differentiate to osteocytes, hepatocytes, chondrocytes, myocytes and etc,.
- Trial name
- NCT00420134
- Testing
- injection of progenitor of hepatocyte drived from Mesenchymal stem cell
- Where
- 2 sites in Iran
- Volunteers
- 30 people
- Sponsor
- Shahid Beheshti University of Medical Sciences