Clinical trials: End Stage Renal Disease
End Stage Renal Disease, Transplantation
Acute Pharmacokinetic-pharmacodynamic Change of Rocuronium After Reperfusion of Renal Graft
Reperfusion of renal graft in kidney transplantation can change the pharmacokinetic-pharmacodynamic (PKPD) parameters of rocuronium.
- Trial name
- NCT02827435
- Testing
- Rocuronium bromide
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Hospital
End Stage Renal Disease
A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)
This study is designed to assess the pharmacokinetics (PK) and safety of oseltamivir and its metabolite oseltamivir carboxylate in participants undergoing routine HD and CAPD for end-stage renal disease (ESRD).
- Trial name
- NCT02617784
- Testing
- Oseltamivir
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
Hyperphosphatemia, Kidney Failure
A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis
This is up to a 58 week study comparing ferric citrate to active control for 52 weeks in ESRD dialysis patients, and subsequently comparing ferric citrate to placebo for 4 weeks.
- Trial name
- NCT01191255
- Where
- 56 sites in United States, Israel and 1 more
- Volunteers
- 441 people
- Sponsor
- Keryx Biopharmaceuticals
Cardiovascular Diseases
The Fish and Fruit Study: Trial of Fish and Fruit to Improve Survival of Aboriginal People With End Stage Renal Disease
Cardiovascular disease is the main cause of death in patients on dialysis for end stage renal disease. Omega-3 fatty acids and antioxidants have been shown to be protective in the general population.
- Trial name
- NCT00192543
- Testing
- diet of fish and fruit, fruit and fish, diet only
- Where
- Australia
- Volunteers
- 152 people
- Sponsor
- Menzies School of Health Research
End Stage Renal Disease
Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients
The aim of the study is to evaluate the effect of rutin and vitamin C on selected oxidative stress and inflammatory markrers. Patients will be recruited according to the inclusion and exclusion criteria and will be divided into 3…
- Trial name
- NCT04955145
- Testing
- RUTA C 60
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Ain Shams University
End-stage Kidney Disease
Kinetics of Extracellular Vesicles in Hemodialysis
The aim of this observational study is to gain insight into the kinetics of extracellular vesicles (EVs), derived from both in- (i.e.
- Trial name
- NCT05957146
- Testing
- Routine hemodialysis
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Amsterdam UMC, location VUmc
Kidney Failure, Chronic, Kidney Transplantation
Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation
Kidney transplantation is widely considered to be the treatment of choice for children with End Stage Renal Disease (ESRD). The purpose of this study is to determine the safety of sirolimus monotherapy for long-term…
- Conditions
- Kidney Failure, Chronic, Kidney Transplantation, Immunosuppression
- Trial name
- NCT00768729
- Testing
- Sirolimus, MMF or Azathioprine
- Where
- 5 sites in United States
- Volunteers
- 7 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
End Stage Renal Disease (ESRD), Volume Overload
Blood Volume Monitoring Via Critline in Volume Overload: Hospitalization and Readmission
The investigators are examining how adding relative blood volume monitoring (RBVM) to the best clinical practice affects outcomes (length of stay and rehospitalization) among dialysis patients hospitalized for or with volume…
- Trial name
- NCT07866872
- Testing
- Relative Blood Volume Monitoring (RBVM)
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Renal Disease
A Study to Assess the Pharmacokinetics of Ceftaroline in End Stage Renal Disease Patients and Matched Healthy Subjects
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of Ceftaroline in a group of patients with renal disease and matching healthy subjects with normal renal function
- Trial name
- NCT01664065
- Testing
- 200 mg Ceftaroline fosamil, 600 mg Ceftaroline fosamil
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Kidney Failure, Hemodialysis Patients
Nature-Based Sound Application For Hemodialysis Patients
Chronic renal failure is one of the most common chronic diseases in the world and in our country. Hemodialysis is the most commonly used treatment method in the treatment of chronic renal failure.
- Conditions
- Chronic Kidney Failure, Hemodialysis Patients, Fatigue, Patient Comfort
- Trial name
- NBSAFHP (NCT06165211)
- Testing
- Nature sound listening, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Necmiye ÇÖMLEKÇİ
End Stage Renal Disease on Dialysis
Temperature and Bicarbonate: Hemodynamic Effects During Dialysis
To elucidate the role of dialysate temperature and bicarbonate on hemodynamic parameters, plasma pH and electrolytes that potentially mediate this effect, the investigators wish to conduct a single-blinded, randomized…
- Trial name
- TURBO (NCT05052151)
- Testing
- Low dialysate temperature, High dialysate temperature, Low dialysate bicarbonate concentration
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
End Stage Renal Disease, Thrombosis
Safety and Efficacy Study of AB002 (E-WE Thrombin) in End Stage Renal Disease Patients on Chronic Hemodialysis
This study evaluates the safety and efficacy of AB002 (E-WE thrombin) in patients with end stage renal disease on chronic hemodialysis. Two dose levels will be evaluated in two cohorts.
- Trial name
- NCT03963895
- Testing
- AB002 Dose 1, AB002 Dose 2
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Aronora, Inc.
End Stage Renal Disease, Hemodialysis
The Effect of Pomegranate Juice on Oxidative Stress in Hemodialysis Patients
Pomegranate juice (PJ) consumption by hemodialysis patients will reduce the oxidative stress and the incidence of infections, cardiovascular events and mortality.
- Trial name
- NCT00727519
- Testing
- Pomegranate juice
- Where
- Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Diet Habit, End Stage Renal Disease
DIETary Intake, Death and Hospitalization in Adult With End-stage Kidney Disease Treated With HemoDialysis (DIET-HD) Study
The DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study is a multinational prospective cohort study designed to evaluate the association between nutrition…
- Trial name
- NCT03125265
- Testing
- dietary intake of omega-3 and omega-6 polyunsaturated fatty acids
- Volunteers
- 9,757 people
- Sponsor
- Giovanni Strippoli
Renal Insufficiency, Chronic, Anxiety
AI-Guided Personalized Relaxation for Hemodialysis Patients
Patients undergoing maintenance hemodialysis frequently experience impaired health-related quality of life, anxiety, and difficulties in coping with the long-term demands of treatment.
- Conditions
- Renal Insufficiency, Chronic, Anxiety, Relaxation Therapy, Maintenance Hemodialysis
- Trial name
- NCT07522944
- Testing
- AI-Guided Relaxation Platform, Standard Hemodialysis Nursing Care
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Alexandria University
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).
Recent advances in continuous glucose monitors (CGMs) and availability of commercial CGM products to patients with type 1 and type 2 diabetes has made the use of CGM more widespread.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT04094064
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
End-Stage Renal Disease Requiring Haemodialysis, Intradialytic Hypotension
Inferior Vena Cava Collapsibility Index and Intradialytic Hypotension
This multicenter, prospective observational study aims to evaluate the predictive value of the Inferior Vena Cava Collapsibility Index (IVCCI), along with IVC maximum diameter (IVCmax) and IVC minimum diameter (IVCmin), for…
- Trial name
- IVC-HD (NCT07033273)
- Testing
- Non-invasive Monitoring
- Where
- China
- Volunteers
- 188 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Chronic Renal Failure
Clinical Study on Optimised Removal of Protein-bound Uremic Toxins With Convective Dialysis Treatment.
Patients will be treated with hemodiafiltration (HDF) in postdilution mode, as a control therapy, during 9 weeks. During week 5 the 1st intervention treatment, predilution hemofiltration (HF) or predilution HDF, will be performed…
- Trial name
- NCT00337831
- Testing
- Performance of predilution hemofiltration, predilution hemodiafiltration or postdilution hemodiafiltration
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- University Hospital, Ghent
Chronic Kidney Disease Requiring Hemodialysis, End Stage Renal Disease (ESRD)
Early Feasibility Study of the Velocity™ Percutaneous Arterio-Venous Fistula System for Creating Hemodialysis Vascular Access
The Velocity Percutaneous Arterio-Venous System is a minimally invasive method of creating hemodialysis vascular access. The study aims to understand clinical efficacy and initial clinical safety data of the device.
- Trial name
- VENOS-2 (NCT06712251)
- Testing
- Velocity pAVF System
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- Venova Medical
Renal Failure, Chronic Renal Insufficiency
Inspiratory Muscle Training in Patients With End Stage Renal Failure
This study will investigate whether inspiratory muscle training in patients with end stage renal failure can improve strength and function.
- Trial name
- NCT01347775
- Testing
- Inspiratory muscle training (URES HS730)
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- The University of Queensland