Clinical trials: End Stage Renal Failure
End Stage Renal Disease, Chronic Kidney Disease
Study to Assess Fixed Dosing of AMG 223 in Subjects With Chronic Kidney Disease on Hemodialysis With Hyperphosphatemia
The primary objectives of this study are the following: 1. To demonstrate that AMG 223 will produce a statistically significant reduction in serum phosphorus compared with placebo over a 3 week treatment period in subjects with…
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease, Hyperphosphatemic, Kidney Disease
- Trial name
- NCT00530114
- Testing
- AMG 223
- Volunteers
- 167 people
- Sponsor
- Amgen
End Stage Renal Disease
Safety and Effects of Supplementation With Ergocalciferol on Erythropoietin Dosing in Hemodialysis Patients
A few studies have reported erythropoiesis-stimulating agent (ESA) doses before and after 25D supplementation, but only one of these is a prospective clinical trial, and it is a small, single center study lacking a control arm.
- Trial name
- NCT01395823
- Testing
- ergocalciferol supplementation
- Where
- 12 sites in United States
- Volunteers
- 470 people
- Sponsor
- Dialysis Clinic, Inc.
End-stage Renal Failure, Kidney Graft Rejection
Reference Group Trial for The ONE Study
To investigate the progression of the immunological response in living-donor kidney transplant recipients treated with a standard immunosuppressive regimen.
- Trial name
- NCT01656135
- Testing
- Blood drawing for immune monitoring and questionnaires
- Where
- 8 sites in United States, France and 3 more
- Volunteers
- 70 people
- Sponsor
- University of Regensburg
End Stage Renal Disease
Conventional Hemodialysis Vs Short Daily Hemodialysis for Patients Coming From Peritoneal Dialysis (HAPD/CAPD)
The purpose of this randomized study is to determine if the home SDHD is a suitable alternative to conventional dialysis performed in a dialysis center for patients suffering from chronic kidney disease from Peritoneal Dialysis…
- Trial name
- CHDvsSDHD (NCT02002949)
- Testing
- Short daily hemodialysis, Conventional hemodialysis
- Where
- 31 sites in Italy
- Volunteers
- 144 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Hemodialysis, End Stage Renal Disease
Effects of Omega 3 in Hemodialysis Patients
The aim of the study was to determine the effects of a 3-week fish oil oral supplementation on the metabolic fate and thermogenic effect of an oral glucose load in hemodialysis patients.
- Trial name
- NCT00431899
- Testing
- fish oil supplementation
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Laboratoire Régional de Nutrition Humaine
Influenza, End Stage Renal Failure
Immunogenicity of a Trivalent Influenza Vaccine in Chronic Kidney Disease Patients Undergoing Hemodialysis
During the 2013-2014 influenza season, CKD patients undergoing HD participated in the study. The patients were randomized into two groups (MF59-adjuvanted vaccine group or non-adjuvanted vaccine group) and were immunized with the…
- Conditions
- Influenza, End Stage Renal Failure, Chronic Kidney Disease
- Trial name
- NCT02686398
- Testing
- Fluad, Agrippal
- Volunteers
- 174 people
- Sponsor
- Korea University Guro Hospital
Stroke, End Stage Renal Disease
Randomised Control Trial for Improving Functional Outcome From Stroke in End Stage Renal Disease Patients
TITLE Randomised Control Trial (RCT) for improving functional outcome from stroke in renal disease patients DESIGN Eandomised Conrol Study AIMS 1.
- Trial name
- NCT01656213
- Testing
- Computer-based target pursuit task (created using E-Prime software) and visual-feedback handgrip force transducer (CurrentDesigns 2012).
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Imperial College London
End Stage Renal Disease
A Multiple-Dose Study of Oral Oseltamivir in Participants on Hemodialysis (HD) and Continuous Ambulatory Peritoneal Dialysis (CAPD)
This study is designed to assess the pharmacokinetics (PK) and safety of oseltamivir and its metabolite oseltamivir carboxylate in participants undergoing routine HD and CAPD for end-stage renal disease (ESRD).
- Trial name
- NCT02617784
- Testing
- Oseltamivir
- Where
- New Zealand
- Volunteers
- 24 people
- Sponsor
- Hoffmann-La Roche
End Stage Renal Disease, Hyperphosphatemia
A Dose Escalation Study of VS-505 in End Stage Renal Disease Patients Undergoing Hemodialysis
The purpose is to evaluate the tolerability, safety and efficacy of VS-505 when given with meal for 8 weeks to hemodialysis patients with hyperphosphatemia
- Trial name
- NCT02469467
- Testing
- VS-505
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- KDL Inc.
End Stage Renal Disease
The Desensitization Therapy With GB-0998 for Anti-donor Antibody-positive Recipients.
It is intended to examine the safety and efficacy of desensitization therapy by GB-0998 (intravenous immunoglobulin) for the anti-donor antibody positive recipient in need of pre-transplant desensitization.
- Trial name
- NCT02032095
- Testing
- GB-0998
- Where
- Japan
- Volunteers
- 17 people
- Sponsor
- Japan Blood Products Organization
End-Stage Renal Disease, Pruritus
Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus
The purpose of this study is to determine whether Fumaria Parviflora L. can minimize severity of pruritus in patients with end-stage renal disease.
- Trial name
- NCT02671162
- Testing
- Wheat, Fumaria
- Volunteers
- 63 people
- Sponsor
- Shiraz University of Medical Sciences
End-stage Renal Disease
Study of High Sensitive Troponin-I Level in End-stage Renal Disease Patients Receiving Hemodialysis
This study objective is to compare the high sensitive troponin-I level in end-stage renal disease patients received hemodialysis without acute cardiovascular event with healthy population.
- Trial name
- NCT02572466
- Testing
- Hemodialysis
- Where
- Thailand
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
End Stage Renal Disease, Chronic Kidney Disease
Risk Stratification in End Stage Renal Disease (ESRD) - ISAR Study
The purpose of this study is to evaluate the use of non-invasive markers of the autonomic function and micro- and macrocirculation to predict mortality and cardiovascular end points in end-stage renal disease patients.
- Conditions
- End Stage Renal Disease, Chronic Kidney Disease, Cardiovascular Event, Sudden Cardiac Death
- Trial name
- ISAR (NCT01152892)
- Where
- 17 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Technical University of Munich
End Stage Renal Disease
Effect of Icodextrin Solution on Preservation of Residual Renal Function in Patients on Peritoneal Dialysis
Peritoneal dialysis (PD) is an established dialysis modality in patients with end stage renal disease (ESRD). However, there is growing awareness of the deleterious effect of high glucose content in PD solutions on the peritoneal…
- Trial name
- NCT01170858
- Testing
- Icodextrin PD solution, glucose solutions
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Diabetes Mellitus Type 2, End Stage Renal Disease
Surrogate Markers for Sudden Cardiac Death in Patients With Diabetes Mellitus and End Stage Renal Disease
Aim: Patients with type 2 diabetes mellitus (T2DM) and hemodialysis due to diabetic nephropathy exhibit a high risk for sudden cardiac death (SCD).
- Trial name
- NCT02001480
- Testing
- 12 lead Holter, CGM Continuous Glucose Monitoring
- Where
- 3 sites in Germany
- Volunteers
- 60 people
- Sponsor
- RWTH Aachen University
End-stage Kidney Disease, End-stage Renal Disease
The Optiflow Patency and Maturation Study
The objective of this study is to assess the performance and safety of the Optiflow Anastomotic Connector (Optiflow) when used to facilitate the creation of autogenous arteriovenous fistula (AVF) anastomoses.
- Trial name
- OPEN (NCT01921933)
- Testing
- Optiflow
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Bioconnect Systems, Inc
End Stage Renal Disease
Choice Sets for Advance Directives
There is a large gap between the care seriously ill patients want and the care they receive. Advance directives (ADs) offer an opportunity for patients to express specific end-of-life preferences to avoid unwanted care.
- Trial name
- NCT02209038
- Testing
- Expanded AD Choice, Expanded Life-sustaining Therapy Choice
- Where
- 15 sites in United States
- Volunteers
- 321 people
- Sponsor
- University of Pennsylvania
End Stage Renal Disease
Short Daily Hemodialysis and Online HDF: Which One is Better?
1. To compare the efficacy of 1. Short Daily Hemodialysis 2. Online HDF in term of adequacy of dialysis.
- Trial name
- SHD (NCT00939445)
- Testing
- Online HDF, Short Daily Hemodialysis
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
End Stage Renal Failure on Dialysis
Hemodialysis Blood Flow and Urea Clearance
The study purpose is to determine whether two different hemodialysis blood flow rates each meet national dialysis standards for urea clearance. Urea is used as the primary marker of dialysis adequacy.
- Trial name
- NCT02484118
- Testing
- Hemodialysis blood flow
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of British Columbia
End-Stage Renal Disease, Kidney Failure
Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation
In a non-blinded pilot study conducted at the University of Nebraska Medical Center, evidence was found that a single large dose of Thymoglobulin on the day of kidney transplantation produced better kidney function than the…
- Trial name
- STAT (NCT00906204)
- Testing
- Single-dose rabbit Anti-thymocyte Globulin induction, Divided-dose rabbit Anti-thymocyte Globulin induction
- Where
- 4 sites in United States
- Volunteers
- 99 people
- Sponsor
- Wright State University