Clinical trials: End of Life Communication
Maternal Mortality, Maternal Morbidity
An Implementation Study of Interventions to Promote Safe Motherhood in Jimma Zone Ethiopia
Ethiopia has one of the highest rates of maternal mortality among all countries in Africa and indeed worldwide, with a maternal mortality ratio of 676 per 100,000 live births in 2011 (UNFPA, 2012).
- Trial name
- NCT03299491
- Testing
- MWA intervention, IEC intervention
- Volunteers
- 3,784 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Palliative Care, Communication
Timely End-of-Life Communication to Parents of Children With Brain Tumors
A national priority for health care providers is to initiate early communication about palliative and end-of-life care (PC/EOL) for children with a poor prognosis.
- Trial name
- NCT01170000
- Where
- 4 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The Foundation for Barnes-Jewish Hospital
Terminal Illness, Critical Illness
Targeting Bias to Reduce Disparities in End of Life Care
This study aims to determine the ways in which clinician implicit racial biases affect clinician communication with family members of patients near the end of life and to test a novel physician training intervention to reduce the…
- Trial name
- BRiDgE-Sim (NCT05165888)
- Testing
- Communication and Bias Mitigation Training, Communication skills training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
End Stage Disease
Effects of a Structured Advance Care Planning Guide Among Patients With Advanced Illness in Hospital Care Settings
Objective: To examine the effects of a structured advance care planning (ACP) guide among patients with advanced illness in hospital care setting.
- Trial name
- NCT03599310
- Testing
- Advance care planning, Usual care
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- Food and Health Bureau, Hong Kong
Patient Engagement, End of Life
Advance Care Planning for Older Latinos With Chronic Illness
The goal of this study is to test the feasibility of a randomized controlled trial to learn about implementation of an intervention model, Advance Care Planning I Plan (ACP-I Plan), among older Latinos with chronic illnesses in…
- Conditions
- Patient Engagement, End of Life, Chronic Disease, Communication
- Trial name
- NCT06081660
- Testing
- ACP-I Plan
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Tissue and Organ Procurement
Communication Regarding Organ and Tissue Donation in Intensive Care
The overarching aim of this study is to examine the process of organ donation decision-making and to determine whether changes in requesting practices change rates of consent for donation, and other family-based outcomes.
- Trial name
- COMFORT (NCT01922310)
- Testing
- Communication intervention
- Where
- 10 sites in Australia
- Volunteers
- 417 people
- Sponsor
- NSW Organ and Tissue Donation Service
Communication Research
Using a Nurse-Led Communication Strategy for Surrogates in the Intensive Care Unit
Communication is one of the greatest health needs for high quality end-of-life (EOL) care in the intensive care unit (ICU), especially when patients are too ill to speak for themselves and rely on surrogates to make EOL…
- Trial name
- NCT03770481
- Testing
- nurse-led communication strategy
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Neoplasms (Cancer / Tumors), Palliative Care
Nurse-Led Culturally Adapted Palliative and End-of-Life Training for Oncology Nurses in Oman
This study evaluated a nurse-led, culturally adapted training program in palliative and end-of-life care (N-PELTP) for oncology nurses in Oman.
- Conditions
- Neoplasms (Cancer / Tumors), Palliative Care, Terminal Care
- Trial name
- N-PELTP (NCT07460570)
- Testing
- N-PELTP Palliative and End-of-Life Training Program
- Where
- 2 sites in Oman
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Ethics, Narrative
Ethical Deliberation in the Intensive Care Unit, Impact of Formalized Multidisciplinary Team Meetings, a Pilot Study
Most patients who die in the intensive care unit do so after a withholding or withdrawing of life sustaining treatments (WWLST) decision.
- Trial name
- NCT05722431
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Tours
CPR Decision-Making
Improving Decisions About CPR
Objective The primary objective is to evaluate the efficacy of a multi-faceted, clinical decision support intervention aimed at improving the quality of decisions about Cardio Pulmonary Resuscitation (CPR) for seriously ill…
- Trial name
- iCANACP (NCT03287895)
- Testing
- Decision Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Multiple Myeloma, Myelodysplastic Syndromes
Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT)
Patients diagnosed with hematologic cancer are at substantial risk of dying, as 5-year survival among patients with acute myeloid leukemia is 20 % and only every second patient treated for incurable myeloma lives 5 years after…
- Conditions
- Multiple Myeloma, Myelodysplastic Syndromes, Lymphoma, Acute Myeloid Leukemia
- Trial name
- ACT (NCT05444348)
- Testing
- Advance consultation concerning your life and treatment (ACT )
- Where
- 7 sites in Denmark
- Volunteers
- 920 people
- Sponsor
- Christoffer Johansen
SUDEP, Epilepsy
Improving Patient Communication About SUDEP
Children with generalized tonic-clonic seizures (GTCS) have about a 1 in 4500 of succumbing to sudden unexpected death in epilepsy (SUDEP).
- Trial name
- NCT03502759
- Testing
- CHICA SUDEP module
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Indiana University
Death, Communication, Multidisciplinary
Preserving Compassionate End of Life Care in the Pandemic
Compassionate and humanistic care for patients dying in the hospital has been especially challenging during the pandemic. Family presence is restricted, maximal barrier precautions are advised, and personal protective equipment…
- Conditions
- Death, Communication, Multidisciplinary, Empathy, Compassion
- Trial name
- NCT04602520
- Testing
- 3 Wishes Project
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McMaster University
Palliative Care
Efficacy of End-of-life Communication Strategies on Nurses in the Intensive Care Unit
Burnout among healthcare workers is frequently reported, and one of the factors cited is the stress caused by end-of-life care. It has been reported that nursing staff experience decreased well-being as a result of being involved…
- Trial name
- NCT06211816
- Testing
- communication strategy
- Where
- Japan
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maebashi Red Cross Hospital
Oral Mucositis, Quality of Life
Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
Head and Neck cancer patients receiving radiation therapy (with or without chemotherapy) suffer several oral complications, such as oral mucositis, which impairs quality of life of patients during radiotherapy and in the…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- NCT07739771
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Mucosa Innovations, S.L.
Oncology
Remote Education Strategies Training Oncology Residents for End-of-Life Discussions
Difficult conversations are common in oncology practice and patient-centered communication is essential to care for individuals with cancer.
- Trial name
- RESTORED (NCT05810987)
- Testing
- RESTORE, Medical Interaction and Coaching
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- McMaster University
Terminally Ill
End-of-life Communication From a Chinese Perspective
The goal of this observational study is to explore experiences and perceptions of end-of-life communication in Chinese terminally ill patients, families and healthcare providers.
- Trial name
- NCT05734781
- Testing
- Not Application as this is a qualitative study
- Where
- China
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Cancer
Building Evidence for Effective Palliative/End of Life Care for Teens With Cancer
To test the efficacy of FACE-TC on key outcomes, the investigators propose using an intent-to-treat, longitudinal, prospective, multi-site, randomized controlled trial (RCT) design.
- Trial name
- FACE-TC (NCT02693665)
- Testing
- FAmily CEntered Advance Care Planning for Teens with Cancer
- Where
- 4 sites in United States
- Volunteers
- 260 people
- Sponsor
- Maureen Lyon
Other Diagnoses, Comorbidities, and Complications
Assessing the Efficacy of an Electronic Discharge Communication Tool
The transition between acute care and community care represents one of the most vulnerable periods in health care delivery, particularly as the complexity of inpatient populations increases.
- Trial name
- NCT01402609
- Testing
- electronic discharge communication tool, Usual care
- Where
- 2 sites in Canada
- Volunteers
- 1,399 people
- Sponsor
- Ward of the 21st Century
Neonatal Death, Perinatal Death
CHV-NEO: Community-based Digital Communication to Support Neonatal Health
Neonatal mortality (defined as death in the first 28 days of life) remains unacceptably high in sub-Sarahan Africa. The concentrated risk of neonatal illness in the first weeks of life and its potential to rapidly deteriorate…
- Trial name
- NCT05187897
- Testing
- CHV-NEO
- Where
- Kenya
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Washington