Clinical trials: End of Life Communication
Ischemic Stroke, Ischaemic Stroke With Coma
Decision Aid Feasibility Trial for Families of Critically Ill Stroke Patients
Severe strokes, including large artery acute ischemic stroke and intracerebral hemorrhage, continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Ischemic Stroke, Ischaemic Stroke With Coma, Intracerebral Hemorrhage, Hemorrhagic Stroke
- Trial name
- NCT04143113
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Sponsor
- University of Massachusetts, Worcester
Patients Died in Intensive Care Unit (ICU)
Guiding ICU Physicians' Communication and Behavior Towards Bereaved Relatives
As ICU mortality is high, end-of-life is a subject of major concern for intensivists. With a mortality rate of 20%, end-of-life care has become a daily responsibility.
- Trial name
- COSMIC (NCT02955992)
- Testing
- Improving communication during the end-of-life process
- Where
- 10 sites in France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD)
Improving Clinician Communication Skills (ICCS)
This research study is a randomized trial to evaluate a training program that is designed to improve the communication skills of clinicians.
- Conditions
- Advanced Cancer, Chronic Obstructive Pulmonary Disease (COPD), Restrictive Lung Disease, Congestive Heart Failure
- Trial name
- ICCS (NCT00687349)
- Testing
- Training Program Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,086 people
- Sponsor
- University of Washington
Death
South Florida Residents Knowledge and Opinions on End-of-Life Issues
The goal of this cross-sectional study is to gain an understanding of the knowledge and attitudes regarding end of life issues and hospice care among a sample of residents of South Florida.
- Trial name
- NCT01008241
- Testing
- Paper questionnaire
- Where
- 2 sites in United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- Maria Isabel Fernandez
Severe Sepsis
End-of-life Decision-making in Patients With Sepsis-related Organ Failure
The care of patients with sepsis-related organ failure on the intensive care unit (ICU) often includes end-of-life decision (EOL-D) and communication of such decisions to relatives.
- Trial name
- EIDECS (NCT01247792)
- Testing
- SOPs for decision-making and communication
- Where
- Germany
- Volunteers
- 174 people
- Sponsor
- Center for Sepsis Control and Care, Germany
End of Life Communication
An Educational Intervention to Improve Resident Comfort With Communication at the End of Life
The purpose of this study is to investigate whether the addition of teaching on communication at the end of life to the pre-existing resident curriculum will positively impact residents' knowledge and attitudes regarding…
- Trial name
- NCT01150968
- Testing
- End of life education
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of California, San Francisco
Implantable Defibrillator User, Terminal Illness
GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers
The purpose of this study is to determine the feasibility and efficacy of the GAMification to Encourage End-Of-Life (GAME-EOL) intervention, which uses the Hello Game program to encourage and facilitate quality end-of-life (EOL)…
- Trial name
- GAME-EOL (NCT04994782)
- Testing
- GAME-EOL
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Debra Moser
Decision Making ,Shared, Leadership
Coaching Doctors and Nurses to Improve Ethical Decision-making in Team
Literature and a pilot study performed in 2019 indicate room for enhancing openness to discuss ethical sensitive issues within and between teams, and improving goal-oriented care and decision-making for the benefit of the patient…
- Conditions
- Decision Making ,Shared, Leadership, End of Life Communication, End of Life Decision Making
- Trial name
- CODE II (NCT07327450)
- Testing
- Usual Care Group, CODE II intervention
- Where
- Belgium
- Volunteers
- 360 people
- Sponsor
- University Hospital, Ghent
End Stage Renal Disease and Kidney Transplantation
Communicating About Choices in Transplantation
The purpose of this study is to test the impact of a newly developed educational program on kidney transplant candidates' communication about living and deceased donor kidney transplantation.
- Trial name
- COACH (NCT01853007)
- Testing
- COACH Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Colonic Neoplasms, Breast Neoplasms
End-of-Life Care for African Americans
Racial differences in health care are documented across the health care continuum and persist in aging and end-of-life (EOL) care.
- Conditions
- Colonic Neoplasms, Breast Neoplasms, Lung Neoplasms
- Trial name
- NCT02320123
- Testing
- Educational DVD
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Oral Mucositis, Quality of Life
Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z, 12Z)-octadeca-9,12-dienoic acid; octadecanoic acid…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- STOPOMP (NCT05635929)
- Testing
- XCM-OM118 Composition comprising olive oil, betaine and xylitol
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Mucosa Innovations, S.L.
End of Life Care, Advanced Cancer
Empathetic Communication Facilitation Program for Early Initiation of End-of-life Discussions
Background: The National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: palliative care recommends discussing advance care planning (ACP) when patients' estimated life expectancy is reduced from a year to…
- Conditions
- End of Life Care, Advanced Cancer, Recurrent Cancer
- Trial name
- NCT05045040
- Testing
- Mobile-based empathetic communication support program to promote ACP discussion
- Where
- Japan
- Volunteers
- 264 people
- Sponsor
- Yosuke Uchitomi
Discrimination, Racial, Communication
PRISM Race and Communication Pilot RCT
This is a pilot randomized trial of 60 patients to test feasibility, acceptability and efficacy of PRISM to improve resilience and facilitate improved patient-clinician communication in racially minorities patients with serious…
- Conditions
- Discrimination, Racial, Communication, Chronic Illness, Bias, Racial
- Trial name
- NCT04915079
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Washington
Death, Communication, Multidisciplinary
A Multicenter Implementation Study of the 3 Wishes Project
The 3 Wishes Project (3WP) was created to promote the connections between patients, family members, and clinicians that are foundational to empathic end-of-life care.
- Conditions
- Death, Communication, Multidisciplinary, Empathy, Compassion
- Trial name
- 3WP (NCT04147169)
- Testing
- Focused end-of-life conversations to promote connections among patients, family members and clinicians.
- Where
- Canada
- Volunteers
- 730 people
- Sponsor
- McMaster University
Chronic Kidney Disease
Shared Decision Making and Renal Supportive Care
This year, 90,000 Americans with end-stage renal disease (ESRD) will die and questions will legitimately be raised as to whether terminal treatment and location of death adequately represented their preferences.
- Trial name
- SDMRSC (NCT02405312)
- Testing
- advance care planning
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baystate Medical Center
Dementia, Chronic Disease
Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)
The objective of this protocol is to test the effectiveness of a Jumpstart intervention on patient-centered outcomes for patients with chronic illness by ensuring that they receive care that is concordant with their goals over…
- Conditions
- Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms
- Trial name
- PICSI-H (NCT04283994)
- Testing
- Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart
- Where
- 3 sites in United States
- Volunteers
- 756 people
- Sponsor
- University of Washington
MLD, Krabbe Disease
Longitudinal Study of Neurodegenerative Disorders
The purpose of this study is to understand the course of rare genetic disorders that affect the brain. This data is being analyzed to gain a better understanding of the progression of the rare neurodegenerative disorders and the…
- Conditions
- MLD, Krabbe Disease, ALD, MPS I
- Trial name
- NCT03333200
- Testing
- Palliative Care, Hematopoetic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Chronic Kidney Diseases
A Pilot Study of The CKM JumpStart Tool
This is a randomized pilot study to test the feasibility and acceptability of a tool to promote discussion about conservative kidney management (CKM) among older patients with advanced CKD and their providers.
- Trial name
- NCT05753020
- Testing
- CKM Jumpstart Tool
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pulmonary Disease, COPD
Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)
The purpose of this study is to evaluate a multifaceted intervention to improve the quality of end-of-life communication between patients with COPD and their primary care providers using information about patients preferences for…
- Conditions
- Pulmonary Disease, COPD, Chronic Bronchitis, Emphysema
- Trial name
- NCT00106080
- Testing
- Audit and Feedback
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- VA Office of Research and Development
HIV
Palliative Care in People Living With HIV/AIDS: Integrating Into Standard of Care
Our goal is to advance palliative care with persons living with AIDS (PLWA) or life-limiting co-morbidities to decrease suffering and increase quality of life (QOL).
- Trial name
- FACE (NCT01775436)
- Testing
- FAmily-CEntered Advance Care Planning, Healthy Living Control
- Where
- 5 sites in United States
- Volunteers
- 444 people
- Sponsor
- Children's National Research Institute