Clinical trials: End of Life Decision Making
Kidney Failure, End of Life
Feasibility Testing a shareD dEciSIon Making Intervention for People With Kidney failuRE, Their Relatives, and the Health Professionals in Kidney Services: a Pilot Randomized Controlled Trial Study Protocol
The aim of this research is to test the acceptability and feasibility of a shared decision making intervention and a patient decision aid to support patients with kidney failure, relatives, and health professionals in planning…
- Trial name
- DESIRE (NCT05842772)
- Testing
- Shared decision making intervention for patients with kidney failure when planning end-of-life care
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- University of Aarhus
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making
The goal of this research agenda is to improve the quality of end-of-life care by explicitly identifying values that will guide the decision-making process, with a particular emphasis on the role of ethnic, racial and cultural…
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cirrhosis, Colon Carcinoma
- Trial name
- Aim3 (NCT00122135)
- Testing
- Values Inventory (VI)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Anxiety, Depression
Improving Patient and Family Centered Care in Advanced Critical Illness
One in five deaths in the U.S. occurs in or shortly after discharge from an intensive care unit (ICU), typically following decisions made by surrogate decision makers to forego life prolonging treatment.
- Trial name
- PARTNER (NCT01844492)
- Testing
- The PARTNER Intervention, ICU Usual Care Control
- Where
- United States
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Death
Advance Directives and End-of-life Decision Making in Intensive Care Medicine in Germany
Description of the decision making process as well as the practices of end of life care in an ICU of a German university hospital during the period when changes of German legislation occurred.
- Trial name
- NCT01294189
- Where
- Germany
- Volunteers
- 224 people
- Sponsor
- Charite University, Berlin, Germany
Communication, Advance Directives
Choice of Diction's Effect
The purpose of the research is to determine how the language used when discussing preferences about cardiopulmonary resuscitation (CPR) affects decisions regarding this (code status)
- Conditions
- Communication, Advance Directives, Decision Making, Cardiopulmonary Resuscitation
- Trial name
- CODE (NCT04896411)
- Testing
- Alternative phrasing for no code, Standard of care for no code
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Obstructive Pulmonary Disease Severe
A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family
This study aims to support EOL decision-making in patients with advanced COPD and their family members. A parallel two-arm single-blinded randomised controlled trial will be conducted to evaluate the effects of a specific…
- Trial name
- NCT06008210
- Testing
- Decision Support Intervention, Health Coaching
- Where
- 2 sites in China
- Volunteers
- 226 people
- Sponsor
- Food and Health Bureau, Hong Kong
Sudden Cardiac Death, Heart Failure
Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy
VIVID is a prospective, multicenter, randomized clinical trial in African American patients that will to evaluate: (1) the effect of an educational video on knowledge of sudden cardiac death (SCD) and implantable cardioverter…
- Trial name
- VIVID (NCT02819973)
- Testing
- Educational Video1, Educational Video 2, Usual Care 3
- Where
- 14 sites in United States
- Volunteers
- 343 people
- Sponsor
- Duke University
Advance Care Planning
Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing
The homeless population is aging, with an increasing proportion of individuals over age 50 who experience accelerated aging, high rates of mortality, and a high risk of not having their wishes honored at the end of life.
- Trial name
- ACP-PSH (NCT06239896)
- Testing
- Facilitated Group ACP Session, Facilitated one-on-one ACP visits
- Where
- 6 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Disease
A Community-based Advance Care Planning Programme for Patients With Advanced Disease
Advance care planning has been recommended as an integral part of care for patients with life-limiting disease, but relevant development in Hong Kong is still in its infancy.
- Trial name
- NCT02068651
- Testing
- Advance care planning programme
- Where
- Hong Kong
- Volunteers
- 239 people
- Sponsor
- Food and Health Bureau, Hong Kong
Urological Cancer
Impact of Mortality Salience on Treatment Decisions
The goal of this clinical trial is to learn if mortality salience has an impact on treatment decisions in urologists and patients with urological cancer.
- Trial name
- MOST-D (NCT06545188)
- Testing
- Mortality Attitudes Personality Survey, Dental treatment questions (control condition)
- Where
- Germany
- Volunteers
- 746 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Advanced Dementia
Advanced Dementia and End-of-life
Palliative and hospice care in advanced dementia: experiences of care givers and benefit of a brochure serving as a decision-making aid Aims: 1.
- Trial name
- NCT03548142
- Testing
- provision of relevant information
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Technical University of Munich
Surrogate Decision Maker, After Death of Patient
The Surrogate Project (Surrogate Storytelling)
Research Protocol Abstract: This is a phase II controlled trial (RCT) of a "storytelling" intervention compared to no treatment among surrogates who have participated in a decision to limit life-sustaining treatment in the ICU…
- Trial name
- NCT01902784
- Testing
- Storytelling Interview
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Pittsburgh
Palliative Care
Proactive Palliative Care Intervention in a Surgical ICU: Influence on Family Satisfaction and Patient Distress
Patients will be identified according to pre-defined trigger criteria for a palliative intervention. One hundred patients of a control group will receive standard intensive care treatment (Usual Care Group).
- Trial name
- PALL-ICU (NCT03287323)
- Testing
- Proactive Palliative Care
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Johannes Gutenberg University Mainz
End of Life Decision Making, Advance Care Planning
An Intervention to Improve End of Life Decision Making Among Homeless Persons
This project is a prospective, randomized controlled trial to improve the end of life experience for homeless persons by facilitating the expression of their wishes and enhancement of their dignity when facing serious illness…
- Trial name
- NCT00471016
- Testing
- Guided intervention
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Ethics, Narrative
Ethical Deliberation in the Intensive Care Unit, Impact of Formalized Multidisciplinary Team Meetings, a Pilot Study
Most patients who die in the intensive care unit do so after a withholding or withdrawing of life sustaining treatments (WWLST) decision.
- Trial name
- NCT05722431
- Where
- France
- Volunteers
- 450 people
- Sponsor
- University Hospital, Tours
Dementia Caregivers, End of Life Decision Making
A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related Decisions
Family caregivers of people with dementia have to decide between tube feeding and hand feeding when persistent eating problems arise.
- Conditions
- Dementia Caregivers, End of Life Decision Making, Advanced Dementia
- Trial name
- NCT07370311
- Testing
- Chinese version of Making Choices Feeding Options for Patients with Dementia Decision Aid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yaolin Pei
CPR Decision-Making
Improving Decisions About CPR
Objective The primary objective is to evaluate the efficacy of a multi-faceted, clinical decision support intervention aimed at improving the quality of decisions about Cardio Pulmonary Resuscitation (CPR) for seriously ill…
- Trial name
- iCANACP (NCT03287895)
- Testing
- Decision Support
- Where
- 2 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Neonatal Mortality, Maternal Mortality
Impact of New Tools of Simulation-enhanced Peer Learning on Neonatal and Maternal Mortality
In the vast majority of developing nations, frontline birth attendants are often the only care providers responsible for newborn care including newborn resuscitation, thermal care, feeding and administration of medications.
- Trial name
- Sim-II (NCT04904380)
- Testing
- Active peer learning
- Volunteers
- 3,456 people
- Sponsor
- Mbarara University of Science and Technology
Alzheimer Disease, Mild Cognitive Impairment
LEADing Dementia End-of-Life Planning Conversations
Advance care planning is important for all adults, but perhaps even more so for the 5.7 million persons with Alzheimer's disease or related dementia (ADRD), due to the progressive and protracted cognitive deterioration associated…
- Trial name
- LEAD (NCT05909189)
- Testing
- LEADing Dementia End-of-Life Planning Conversations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sudden Cardiac Arrest
Educational Videos to Improve Patient Decision Making and Race Disparities in Implantable Cardioverter Defibrillator Use
The investigators will examine whether an educational video increases patient knowledge about heart failure and the risk of sudden cardiac arrest and leads to greater satisfaction with information provided as compared to usual…
- Trial name
- VIVID-01 (NCT00918125)
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Duke University