Clinical trials: End- Stage Renal Disease Patients
Heart Failure With Preserved Ejection Fraction, End Stage Renal Disease on Dialysis
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
The presence of CKD has been linked to the development of HFpEF. Currently, the treatment for HFpEF is limited. SGLT2i are one of the few drug classes that have proven efficacy in HFpEF in randomized controlled trials.
- Trial name
- EMPA-PRED (NCT06249945)
- Testing
- Empagliflozin 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Arteriovenous Fistula Stenosis
Safety and Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells in Preventing Arteriovenous Fistula Stenosis in Patients With End-Stage Diabetic Kidney Disease
A Study on the Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells in Preventing Arteriovenous Fistula Stenosis
- Trial name
- NCT07452822
- Testing
- Human umbilical cord mesenchymal stem cells injection, saline solution
- Volunteers
- 54 people
- Sponsor
- Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Hemodialysis, End Stage Renal Disease
Comparative Effects of Milk Thistle Extract With Vitamin-E in Hemodialysis Patients
For end-stage renal disease (ESRD) patients, cardiovascular disease remains the single most common cause of excess morbidity and mortality.
- Trial name
- NCT01001845
- Testing
- Milk Thistle extract, vit E, vit E + Milk Thistle extract
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Shiraz University of Medical Sciences
End-Stage Renal Disease
Anti-Cytokine Therapy for Hemodialysis InflammatION
Anti-Cytokine Therapy for Hemodialysis InflammatION (ACTION) is a phase II multi-center study to evaluate the safety and tolerability of anakinra, an IL-1 receptor antagonist, for patients treated with maintenance hemodialysis.
- Trial name
- ACTION (NCT03141983)
- Testing
- Anakinra
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
End-stage Renal Disease (ESRD), Peritoneal Dialysis (PD)
Amino Acid (15) Peritoneal Dialysis Solution for Nutritional Improvement in Peritoneal Dialysis Patients
The goal of this clinical trial is to assess whether Amino Acid (15) Peritoneal Dialysis Solution can improve the nutritional status of adults with end-stage kidney disease who have received peritoneal dialysis for 6 months or…
- Conditions
- End-stage Renal Disease (ESRD), Peritoneal Dialysis (PD), Nutritional Status, Renal Replacement Therapy
- Trial name
- AA15-PD-Nut-SH (NCT07370441)
- Testing
- amino acid (15) peritoneal dialysis solution
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai 10th People's Hospital
Chronic Renal Failure, Hemodialysis Treatment, Protein-energy Wasting
Effect of Intradialytic Physical ACTIvity in Addition to a NUTritional Support on Protein Energy Wasting and Physical Functioning in Chronic Hemodialysis Patients ("ACTINUT" Study)
Sedentary behavior and protein-energy wasting (PEW) are well known risk factors of adverse outcome and low quality of life in chronic renal failure patients treated by dialysis.
- Trial name
- ACTINUT (NCT01813851)
- Testing
- Exercise training in addition to nutritional support
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Nantes University Hospital
End-stage Renal Disease
Efficacy Trial of Fluid Distribution Timetable
Nonadherence to fluid restriction is a significant issue among hemodialysis patients globally, with numerous adverse health outcomes.
- Trial name
- NCT05797766
- Testing
- Fluid Distribution Timetable
- Where
- Philippines
- Volunteers
- 40 people
- Sponsor
- University of Santo Tomas
Chronic Hepatitis C, End Stage Renal Disease
A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD)
1. A maximally tolerated dose of ribavirin can be defined in each patient with ESRD undergoing hemodialysis. 2. Patients with Chronic Hepatitis C Virus (HCV)and End-Stage Renal Disease (ESRD)undergoing hemodialysis will be able…
- Trial name
- NCT01731301
- Testing
- Ribavirin, Peginterferon, Boceprevir
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Liver Institute of Virginia
Vitamin D Deficiency, End Stage Renal Disease
A Study of Fixed Dose Versus Serum Level-Based Titration Regimen of Vitamin D Supplementation in Dialysis Patients
Vitamin D insufficiency, defined as serum 25-hydroxyvitamin (OH) D level less than 30 ng/ml, is highly prevalent not only in the general population but also in chronic kidney disease (CKD) population.
- Trial name
- NCT05434377
- Testing
- ergocalciferol supplementation, dialysis techniques, sunlight exposure time
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Chulalongkorn University
Chronic Kidney Disease Stage 5
Quality of Life and Depression in Dialysis Patients
The aim of this study is to evaluate quality of life (QOL) and depression in peritoneal dialysis patients compare to hemodialysis patients and assess hydration effect on QOL and depression over time.
- Trial name
- QOLD (NCT01668628)
- Where
- South Korea
- Volunteers
- 1,068 people
- Sponsor
- Fresenius Medical Care Korea
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
A Pragmatic Approach to CKD Patient Education
Over 350,000 adult Arkansans have chronic kidney disease (CKD) and 9 out of 10 (312,000) of these Arkansans are unaware of having it.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Patient Engagement
- Trial name
- PACED (NCT05138419)
- Testing
- CKD "What You Need To Know" Workbook System, CKD Action Plan, CKD Web-based Resource List
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
HIV-1 Infection, Chronic Renal Insufficiency
Renal Transplantation and Raltegravir in HIV-Infected Patients
The aim of this study is to evaluate the incidence of acute renal graft rejection 6 months after transplantation in HIV-infected patients under three antiretroviral drugs regimen including Raltegravir.
- Trial name
- ANRS153TREVE (NCT01453192)
- Testing
- Raltegravir
- Where
- 14 sites in France
- Volunteers
- 27 people
- Sponsor
- ANRS, Emerging Infectious Diseases
End-stage Renal Disease
Vitamin D and Arteriovenous Fistulae
Patients requiring hemodialysis following kidney failure need a form of dialysis vascular access in order to undergo the dialysis procedure. Dialysis vascular access dysfunction is an enormous clinical problem.
- Trial name
- NCT00912782
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Emory University
Arteriovenous Fistulae
Cohort Study on A Following-up System of Native Arteriovenous Fistulae
A cohort including more than 100 maintenance hemodialysis patients will be followed up according to a certain Following-up System of Native Arteriovenous Fistulae (AVF) prospectively.
- Trial name
- NCT02880761
- Testing
- Assessment guiding surgery and puncture for AVF
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Capital Medical University
End Stage Renal Disease on Dialysis
Effects of pHA Hemoperfusion Plus Hemodialysis on Protein-Bound Uremic Toxins
This single-center, prospective cohort Study evaluates whether adding the pHA130 hemoperfusion cartridge to conventional hemodialysis (HD) or hemodiafiltration (HDF) more effectively reduces protein-bound uremic…
- Trial name
- NCT07016841
- Testing
- pHA130 hemoperfusion device, HD/HDF, HA130 hemoperfusion device
- Where
- China
- Volunteers
- 109 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
End Stage Renal Disease and Kidney Transplantation
Communicating About Choices in Transplantation
The purpose of this study is to test the impact of a newly developed educational program on kidney transplant candidates' communication about living and deceased donor kidney transplantation.
- Trial name
- COACH (NCT01853007)
- Testing
- COACH Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Chronic Kidney Diseases
Kidney AI-enabled Care Transformation
In the Kidney ACTion study, CKD (Chronic Kidney Disease) patients at increased risk of progression to ESRD (End Stage Renal Disease) will be randomly assigned to either standard of care in a specialist nephrology outpatient…
- Trial name
- NCT05056909
- Testing
- Kidney ACTion, Standard of care
- Where
- 2 sites in Italy, United Kingdom
- Sponsor
- Medical University of Graz
End Stage Renal Failure, Hemodialysis, Fatigue
Reflexology Versus Progressive Muscle Relaxation for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to compare the effects of reflexology and progressive muscle relaxation in reducing fatigue among hemodialysis patients and to determine which intervention provides greater relief from fatigue.
- Trial name
- PMR-HD (NCT07575607)
- Testing
- reflexology, progressive muscle relaxation, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Emergent Dialysis, Venous Doppler Ultrasound
Sonographic Venous Doppler Imaging in End-Stage Renal Disease
Patients with end-stage renal disease (ESRD) may visit to emergency services for urgent hemodialysis or other reasons. Hemodialysis application in emergency conditions is generally not as optimal as in dialysis units.
- Trial name
- NCT05337384
- Testing
- Sonography
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gazi University
Oral Disease, Chronic Kidney Diseases
Oral Findings in Chronic Kidney Disease
The patients with chronic kidney disease suffer from many oral problems affecting the quality of life. The aim of our study is to assess their oral health to provide the proper management and increase their awareness
- Trial name
- NCT03082365
- Volunteers
- 225 people
- Sponsor
- Maryam Ahmed Essam Abdel Salam
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