Clinical trials: End-Stage Kidney Disease
Chronic Renal Failure
Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD)
This is a multicenter, randomized, double-blind, placebo-controlled clinical trial to investigate the renoprotective efficacy of combined pentoxifylline (PTX) and angiotensin receptor blockers (valsartan), compared with placebo…
- Trial name
- CKD (NCT01377285)
- Testing
- ARB, Pentoxifylline
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Kidney Disease, Chronic, End Stage Renal Disease
The Effect of Exercise on Dialysis Patients' Survival
The purpose of this study is to check if patients' exercise during their dialysis sessions can prevent their early deaths.
- Conditions
- Kidney Disease, Chronic, End Stage Renal Disease, Hemodialysis
- Trial name
- NCT04898608
- Testing
- Intradialytic Exercise
- Where
- 2 sites in Iran
- Volunteers
- 74 people
- Sponsor
- Pardis Specialized Wellness Institute
Chronic Renal Failure
Safety and Efficacy of BMMNC in Patients With Chronic Renal Failure
This Study is single arm, single center trial to check the safety and efficacy of Autologous Bone Marrow derived Mono Nuclear Stem Cell (BMMNCs)for the patient with CRF
- Trial name
- NCT01876017
- Testing
- Intravenous transfer of Autologous (BMMNCs)
- Where
- India
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
End Stage Renal Disease, Dialysis Related Complication
Comparison of Hemodialysis With Medium Cut-off Dialyzer (Theranova) and High Flux Dialyzer
The aim of this study is to evaluate the removal of midle molecules and inflammatory cytokines with the Theranova-500 ™ dialyzer (medium cut-off membrane, Baxter®) versus a high flux dialyzer Elisio-21H ™ (High-flux membrane…
- Conditions
- End Stage Renal Disease, Dialysis Related Complication, Dialysis Amyloidosis
- Trial name
- THERANOVA (NCT03211676)
- Testing
- Theranova-500 dialyzer, Elisio-21H
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Poitiers University Hospital
Acute Renal Failure, Chronic Renal Failure
Effect of Dialysate Temperature on Haemodynamic Stability and Haemodialysis Efficiency
Comparison between dialysate temperatures on haemodynamic stability and haemodialysis efficiency.
- Trial name
- NCT00221598
- Testing
- Haemodialysis with different dialysate temperatures
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Ghent
Hyperkalemia, Chronic Kidney Failure
Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis Patients
The purpose of this trial is to determine if sodium polystyrene sulfonate (SPS) is an effective treatment of mild hyperkalemia in chronic kidney disease patients followed at a pre-dialysis or nephrology outpatient clinic.
- Trial name
- SKIP (NCT02065076)
- Testing
- Sodium polystyrene sulfonate, Lactose with carob gum
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant
Vaccination Against COVID-19 in Chronic Kidney Disease
This is a prospective, multi-center, observational study that will enroll patients receiving dialysis (hemodialysis or peritoneal dialysis) or patients with kidney transplantation who will be vaccinated against COVID-19.
- Conditions
- Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant, Vaccine Response Impaired
- Trial name
- NCT04743947
- Testing
- No intervention; observational study
- Where
- 5 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
End Stage Renal Disease
Pharmacodynamic Study of Two Lanthanum Carbonate Formulations in Healthy Adults
This study is being conducted to assess any potential differences in the absorption and excretion between two lanthanum carbonate formulations.
- Trial name
- NCT00880750
- Testing
- Lanthanum carbonate Granule Formulation, Lanthanum carbonate Chewable Tablets (Fosrenol)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shire
End-Stage Kidney Disease, Chronic Kidney Failure
Animal Assisted Intervention for Hemodialysis Outpatients
The goal of this clinical trial is to understand if and how an animal-assisted intervention [AAI] using therapy dogs can support hemodialysis [HD] patients' treatment adherence and enhance their well-being.
- Conditions
- End-Stage Kidney Disease, Chronic Kidney Failure, Chronic Pain
- Trial name
- NCT06030050
- Testing
- Animal-assisted intervention
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetic Kidney Disease (DKD)
YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study2
Using the practical randomized controlled trial designed by Zelen, the subjects were randomly divided into the experimental group and the control group.
- Trial name
- NCT07034807
- Testing
- the traditional Chinese medicine prescription ' Shenzhuo Decoction ', basic treatment
- Where
- 5 sites in China
- Volunteers
- 228 people
- Sponsor
- Liu Hongfang
End Stage Renal Disease
Safety and Efficacy of Acthar Gel in an Outpatient Dialysis Population
This will be a prospective observational study of Acthar Gel in Non-Diabetic Hemodialysis [NDHD] patients receiving dialysis for ≤ 2 years.
- Trial name
- NCT02486744
- Testing
- Acthar Gel
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Youngstown State University
Stage 5 Chronic Kidney Disease
Risk of Falling in Chronic Kidney Disease 5
The purpose of this study is to explore the relative importance of the frailty and cardiovascular function as potential exercise-modifiable risk factors for falling in patients receiving haemodialysis.
- Trial name
- NCT02392299
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people
- Sponsor
- Queen Margaret University
Chronic Kidney Diseases
Competing Risk of Death and ESRD in Incident CKD Patients
Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed.
- Trial name
- EPIRAN (NCT03379571)
- Volunteers
- 631 people
- Sponsor
- Central Hospital, Nancy, France
Deceased Donor Kidney Transplant, Acute Kidney Injury
Deceased Donor Biomarkers and Recipient Outcomes
Compared to chronic dialysis, kidney transplantation provides recipients with longer survival and better quality of life at a lower cost.
- Conditions
- Deceased Donor Kidney Transplant, Acute Kidney Injury, Delayed Graft Function, End Stage Renal Disease
- Trial name
- DDS (NCT01848249)
- Where
- 17 sites in United States
- Volunteers
- 1,679 people
- Sponsor
- Yale University
Chronic Kidney Diseases, End Stage Renal Disease
Topical Magnesium and Muscle Cramps in Dialysis Patients.
Oral magnesium supplementation has been widely used in the treatment of muscle cramps. Muscle cramps are common in dialysis patients but are not satisfactorily prevented by oral magnesium.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Dialysis Related Complications
- Trial name
- NCT03082625
- Testing
- Transdermal Magnesium
- Volunteers
- 40 people
- Sponsor
- Sir Charles Gairdner Hospital
Chronic Kidney Diseases, Fracture
Denosumab Treatment in CKD Patients at High Risk of Fracture
Objective: To verify the efficacy and safety of denosumab in the prevention and treatment of CKD-MBD in CKD patients with high risk of fracture.
- Conditions
- Chronic Kidney Diseases, Fracture, Bone Density, Low, End Stage Renal Disease
- Trial name
- NCT05692297
- Testing
- Denosumab, Non-denosumab
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Capital Medical University
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, End Stage Renal Disease
Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease
This prospective randomized trial aims to evaluate the feasibility, risk and benefit of the discontinuation of immunosuppressive maintenance treatments in AAV (Antineutrophil Cytoplasmic Autoantibodies (ANCA)-associated…
- Trial name
- MASTER-ANCA (NCT03323476)
- Testing
- Discontinuation (or not initiation) of Immunosuppressive Therapy, Maintenance (or initiation) of immunosuppressive treatment: Imurel®, Mabthera®,Cellcept®, Cortancyl®
- Where
- 57 sites in France
- Volunteers
- 136 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Chronic Renal Insufficiency, End-Stage Renal Disease
A Study in Children With Growth Failure Due to Chronic Renal Insufficiency (CRI) or End Stage Renal Disease (ESRD)
This study is a multicenter, open-label, observational, postmarketing surveillance study that will collect information on the use of Genentech growth hormone (GH) preparations to treat children with CRI in the United States.
- Trial name
- NCT00097617
- Volunteers
- 395 people
- Sponsor
- Genentech, Inc.
Chronic Renal Failure
Relations Between Residual Renal Function and Oxidative and Carbonyl Stress in Peritoneal Dialysis Patients
Residual renal function is reported to contribute to the survival and cardiovascular disease of peritoneal dialysis patients. Oxidative and carbonyl stress are increased in peritoneal dialysis patients and are associated with…
- Trial name
- NCT00692068
- Where
- Japan
- Sponsor
- Iwata City Hospital
End Stage Kidney Disease (ESRD)
STARgraft (10401) Pilot
This study is a single site, prospective, single arm evaluation of the safety and effectiveness of the Healionics STARgraft (10401) hemodialysis access graft.
- Trial name
- NCT07555717
- Testing
- STARgraft (10401)
- Where
- Paraguay
- Volunteers
- 20 people
- Sponsor
- Healionics Corporation
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