Clinical trials: End-Stage Kidney Disease
Chronic Renal Disease, Chronic Renal Insufficiency
2D-speckle Tracking in Pediatric Renal Chronic Disease
The SPECKLE- KIDNEY-PED is a multicentre observational controlled trial aiming to evaluate the 2D-Speckle tracking in a population of 85 patients aged from 6 to 17 years old with a chronic renal disease and to compare the results…
- Conditions
- Chronic Renal Disease, Chronic Renal Insufficiency, Congenital Heart Disease
- Trial name
- SPECKLEKIDNEY (NCT04897672)
- Testing
- Observational study
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease Stage 3, Chronic Kidney Disease
Clinical Effectiveness of MyNutriKidney®
This study is a 6-month, pragmatic, multi-center, sequentially recruited, stratified, open-label randomized controlled trial (RCT) conducted in Malaysia.
- Conditions
- Chronic Kidney Disease Stage 3, Chronic Kidney Disease, Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4
- Trial name
- NCT06956872
- Testing
- Counseling, Renal Diet App, Printed Nutrition Pamphlet
- Where
- Malaysia
- Volunteers
- 200 people
- Sponsor
- Universiti Putra Malaysia
Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
The goal of this clinical trial is to learn if AP301 could work in the patients receiving maintenance dialysis with elevated blood phosphate.
- Conditions
- Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis, ESRD (End-Stage Renal Disease), Dialysis
- Trial name
- RESPOND-2 (NCT06933472)
- Testing
- AP301, AP301 Low Dose
- Where
- 42 sites in United States, China
- Volunteers
- 264 people
- Sponsor
- Alebund Pharmaceuticals
Kidney Disease, Chronic
Oral Findings in a Group of Egyptian Pediatric Patients at Endstage Renal Disease
In Egypt, the prevalence of end stage renal disease in pediatric population has never been estimated on a national scale. The patients at end stage renal disease encounter oral and dental problems that emphasize regular and…
- Trial name
- NCT03590067
- Testing
- Questionnaire
- Volunteers
- 150 people
- Sponsor
- Cairo University
Heart Failure With Preserved Ejection Fraction, End Stage Renal Disease on Dialysis
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
The presence of CKD has been linked to the development of HFpEF. Currently, the treatment for HFpEF is limited. SGLT2i are one of the few drug classes that have proven efficacy in HFpEF in randomized controlled trials.
- Trial name
- EMPA-PRED (NCT06249945)
- Testing
- Empagliflozin 25 MG
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
End-Stage Renal Disease, Stage 5 Chronic Kidney Disease
Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5
Chronic Kidney Disease Stage 5 (CKD5) patients receiving maintenance hemodialysis are at an increased risk for developing bloodstream infections.
- Trial name
- NCT02392208
- Testing
- Telavancin, Pharmacokinetic Blood Sampling
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Michigan
End Stage Renal Disease, Cardiac Insufficiency
Invasive Monitoring of Pulmonary Artery Pressure (PAP) Among Dialysis Treated Patients
The purpose of this study is examine whether invasive pulmonary artery pressure (PAP) monitoring could be beneficial for the patients in dialysis treatment.
- Trial name
- NCT02862197
- Where
- Finland
- Volunteers
- 8 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Peritoneal Dialysis Complication, Hypoalbuminemia
The Effect of Natural Protein vs. Protein Supplements on Peritoneal Dialysis Patients
This study is a prospective open label clinical trial comparing serum albumin levels and total protein intake in the peritoneal dialysis patient population.
- Conditions
- Peritoneal Dialysis Complication, Hypoalbuminemia, Malnutrition
- Trial name
- NCT03569410
- Testing
- increased protein intake via natural foods, increase protein intake via protein supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Anemia in Chronic Renal Disease
Changes in Iron Markers Following Iron Loading in Hemodialysis Patients
The purpose of this study is to describe alterations of serum ferritin, transferrin saturation, soluble transferrin receptor, % hypochromic erythrocytes, % reticulocytes, reticulocyte hemoglobin content after iron loading in…
- Trial name
- NCT00308490
- Testing
- iron sucrose
- Where
- Greece
- Volunteers
- 160 people
- Sponsor
- Papageorgiou General Hospital
Lipoprotein(a), Lipoprotein-apheresis
Case Series : Management of Elevated Lipoprotein(a) Using Double-Filtration Plasmapheresis (DFPP) in Hemodialysis Patients With Chronic Kidney Disease ; ( LiPo-A )
Lipoprotein-apheresis DFPP has been performed in patients with Lp(a) levels greater than 125 nmol/L. In this report, data will be presented on five hemodialysis patients with significantly elevated Lp(a) levels (>200 nmol/L) who…
- Conditions
- Lipoprotein(a), Lipoprotein-apheresis, Double-filtration Plasmapheresis, Hemodialysis Complication
- Trial name
- LiPo-A (NCT07390604)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Aromatherapy (Geranium Essential Oil), Chronic Kidney Disease on Hemodialysis
The Effect of Geranium Essential Oil Aromatherapy on Fatigue and Sleep Quality in Patients Undergoing Hemodialysis
Hemodialysis is a life-sustaining therapy for individuals with chronic kidney disease; however, it is often accompanied by adverse effects such as fatigue and poor sleep quality.
- Conditions
- Aromatherapy (Geranium Essential Oil), Chronic Kidney Disease on Hemodialysis, End Stage Renal Disease (ESRD), Fatigue
- Trial name
- NCT07273825
- Testing
- Geranium Aromatherapy
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Universitas Muhammadiyah Surakarta
End Stage Renal Disease, Haemodialysis
Comparison of Citrate and Heparin Anticoagulation During Hemodialysis With MCO PES-PVP (Theranova) Membrane
The purpose of the study is to compare the efficiency and biocompatibility of citrate and heparin anticoagulation during hemodialysis with medium cut-off polyarylethersulphone-polyvinylpirrolidone membrane (Theranova®).
- Conditions
- End Stage Renal Disease, Haemodialysis, Anticoagulation
- Trial name
- NCT04139525
- Testing
- unfractionated heparin, 8% trisodium citrate
- Where
- Slovenia
- Volunteers
- 32 people
- Sponsor
- Marija Malgaj Vrečko
Diabetes, End Stage Renal Disease
Continuous Glucose Monitoring and Inflammation in Nondiabetic and Diabetic Patients Undergone Hemodialysis
Evaluation of different glycemic variations between the dialysis period and non-dialysis period in two groups: nondiabetic and diabetic patients undergone two different hemodialysis methods.
- Trial name
- NCT01049152
- Testing
- Continuous Glucose Monitoring (CGM)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Pavia
End Stage Renal Disease on Dialysis
Home-based vs Intradialysis Exercise Guided by Nursing Staff
Participants will be randomized either to home-based exercise or to intradialysis exercise guided by nurses of the renal unit. The programs will last 16 weeks.
- Trial name
- HoBIDnurse (NCT04051515)
- Testing
- Intradialysis exercise training, Home-based exercise training
- Where
- 7 sites in Belgium, Greece and 2 more
- Volunteers
- 70 people
- Sponsor
- Cardenal Herrera University
End Stage Kidney Disease
Alio WEAR Study: Long-term Wear of the Alio Platform
The WEAR study is long-term interventional study designed to evaluate patient and clinician use of the Alio platform, per its FDA cleared indications.
- Trial name
- NCT06056739
- Testing
- Alio platform
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Alio, Inc.
End-stage Renal Disease
Network Interventions to Reduce Disparities in Living Kidney Donation
For this current phase of the larger project, the investigators will survey transplant candidates as well as the participants family and friends to understand the barriers to volunteering and evaluation.
- Trial name
- NCT05255757
- Testing
- Script Intervention, Search Intervention
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Penn State University
Chronic Renal Failure
Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure
This study is to evaluate the efficacy of sodium bicarbonate plus N-acetylcysteine for the prevention of contrast-induced nephropathy.
- Trial name
- NCT00716001
- Testing
- N-acetylcysteine
- Sponsor
- Osaka General Medical Center
End Stage Renal Disease, Renal Transplantation
Comparisone of Iminoral Versus Neoral in Prevention of Acute Rejection in Renal Transplantation
Cyclosporine is the key drug in organ transplantation. In Iran the investigators have more than 2500 new renal transplantation each year and because of this the government pay a huge amount of money for subsiding the imported…
- Trial name
- NCT00656695
- Testing
- Iminoral, Neoral
- Where
- Iran
- Volunteers
- 208 people
- Sponsor
- Imam Khomeini Hospital
Renal Failure Chronic Requiring Hemodialysis
Continuous Soluble Ferric Pyrophosphate (SFP) Iron Delivery Via Dialysate in Hemodialysis Patients
The purpose of this study is to confirm the safety and efficacy of Soluble Ferric Pyrophosphate (SFP) dialysate solution in maintaining iron delivery for erythropoiesis in anemic adult patients with chronic kidney disease (CKD)…
- Trial name
- CRUISE 1 (NCT01320202)
- Testing
- Soluble Ferric Pyrophosphate (SFP), Standard dialysate
- Where
- 47 sites in United States, Puerto Rico
- Volunteers
- 305 people
- Sponsor
- Rockwell Medical Technologies, Inc.
End Stage Kidney Disease
Duke APOL1 Research Biorepository
The Duke ApoL1 Nephropathy Biorepository aims to address needs within non-diabetic kidney failure research by utilizing existing and, when necessary, developing new infrastructure to support the consent of patients and the…
- Trial name
- DARB (NCT04160507)
- Testing
- Biorepository
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Duke University
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