Clinical trials: End-Stage Kidney Disease
ESRD (End Stage Renal Disease)
Fluid Status of ESRD Patients Undergoing Dialysis
The pilot clinical study will assess the correlation between fluid removal during dialysis and HemoCept device data.
- Trial name
- NCT07217470
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- HemoCept Inc.
End-stage Renal Disease
Comparison of Cardiac Index and Cardiac Output Effect During Maintenance Hemodialysis Between Acetate-Free and Acetate-Based Online Hemodiafiltration
The purpose of this study is to detemine whether effect of Acetate-free solution on cardiac index and cardiac output measured by saline dilution techniques compares with Acetate-based solution in online-hemodiafiltration
- Trial name
- NCT01778283
- Testing
- Acetate-free dialysis solution
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Chulalongkorn University
End-stage Renal Disease (ESRD)
Creating a Buttonhole Tunnel Track by Repeated Needling of the AV Fistula on the Same Day in Patients on Hemodialysis.
BACKGROUND: The patients diagnosed with end stage renal disease require dialysis and for that they need to have a vascular access for hemodialysis (HD) placed.
- Trial name
- NCT03989141
- Testing
- Repeated cannulation Buttonhole., Single cannulation Buttonhole.
- Where
- 2 sites in Denmark
- Volunteers
- 43 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Chronic Kidney Diseases
Effect of Intradialytic Continuous Versus Interval Aerobic Exercises on Functional Capacity in Patients With Chronic Renal Failure.
Chronic kidney disease has emerged as one of the leading causes of mortality worldwide, and it is one of a small number of non-communicable diseases that have shown an increase in associated deaths over the past 2 decades.
- Trial name
- NCT06173141
- Testing
- low- to moderate-continuous intensity cycling exercises:, moderate- to high-interval intensity cycling exercises, hemodialysis sessions only
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Cairo University
Chronic Renal Failure (CRF)
Evaluation of Electrostimulation Program During Dialysis Sessions in Chronic Renal Failure Patients
Sport improves quality of life and health, decreasing cardiovascular risks and increasing effort tolerance. Chronic renal failure (CRF) induces many clinical and biological complications leading to less effort tolerance (strength…
- Trial name
- EMS-Dialyse (NCT01282554)
- Testing
- electrostimulation program (Rehab 400)
- Where
- 11 sites in France
- Volunteers
- 68 people
- Sponsor
- Rennes University Hospital
Chronic Kidney Failure
Dose Ranging Study of Magnesium Iron Hydroxycarbonate in Haemodialysis Subjects With Hyperphosphataemia
Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb.
- Trial name
- ACT3 (NCT00436683)
- Testing
- Fermagate, Sevelamer HCl
- Where
- 15 sites in United Kingdom
- Volunteers
- 64 people
- Sponsor
- Ineos Healthcare Limited
End-Stage Renal Disease
Evaluation of a Patient Navigation System to Reduce Time to Waitlisting for Potential Kidney Transplant Recipients
The purpose of this study is to measure the effect of introducing a patient navigator to guide high and moderate risk patients through the pre-waitlisting phases of the kidney transplant process.
- Trial name
- NCT01776073
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- Emory University
End Stage Renal Disease, Peritoneal Dialysis
Comparison of Quality of Life on Automated Peritoneal Dialysis and Continuous Ambulatory Peritoneal Dialysis
The objective of this study is to compare Quality of Life (QoL) between Automated Peritoneal Dialysis (APD) and Continuous Ambulatory Peritoneal Dialysis (CAPD).
- Trial name
- EQlips (NCT01209273)
- Where
- 11 sites in South Korea
- Volunteers
- 260 people
- Sponsor
- Kyungpook National University Hospital
End Stage Renal Disease, Hyperphosphatemia
Phosphate Microvascular Study
Elevated phosphate concentrations in the blood have been associated with multiple negative health outcomes in patients with chronic kidney disease as well as in the general population.
- Trial name
- NCT03594539
- Testing
- Withholding standard phosphate binder
- Volunteers
- 20 people
- Sponsor
- Veterans Medical Research Foundation
Chronic Kidney Disease (CKD) Stage 5, Hypertrophy, Left Ventricular
The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5
To evaluate the effects of paricalcitol injection on cardiac structure and function over 48 weeks in subjects with Stage 5 Chronic Kidney Disease (CKD) receiving hemodialysis who have left ventricular hypertrophy (LVH).
- Trial name
- PRIMO II (NCT00616902)
- Testing
- paricalcitol injection 4 mcg/mL
- Where
- 76 sites in United States, Australia and 11 more
- Volunteers
- 12 people
- Sponsor
- Abbott
Fatigue, End Stage Renal Disease
Fatigue in Chronic Haemodialysis Patients: an Experience Sampling Method Study
To investigate the course and diurnal change of fatigue symptoms and haemodialysis related symptoms in chronic haemodialysis patients, its relation to haemodialysis treatment and the association with other factors by implementing…
- Trial name
- FatHoM (NCT04049773)
- Testing
- haemodialysis
- Where
- 2 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Zuyderland Medisch Centrum
Heart Failure, Congestive, Kidney Failure, Chronic
N-Acetylcysteine in Heart Failure With Coexistent Chronic Renal Failure
Treatment with n-acetylcysteine in patients with heart failure and chronic renal failure leads to improvements in vascular function and in renal function.
- Trial name
- NCT00532688
- Testing
- N-acetylcysteine
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Bayside Health
End Stage Chronic Renal Failure, Congestive Heart Failure (CHF)
The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion
The purpose of this study is to evaluate whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard fluid removal rate for patients with advanced kidney disease who are…
- Conditions
- End Stage Chronic Renal Failure, Congestive Heart Failure (CHF), Intravascular Congestion, Fluid Overload
- Trial name
- FILTRATE (NCT07705269)
- Testing
- High-rate ultrafiltration, Standard fluid removal
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Calciphylaxis, Calcific Uremic Arteriolopathy
Phase 2 Study With SNF472 in Calciphylaxis Patients
To evaluate the effect of SNF472 on top of standard of care on promoting wound healing and other parameters of therapeutic response in haemodialysis patients with calciphylaxis (calcific uraemic arteriolopathy, CUA).
- Trial name
- NCT02790073
- Testing
- SNF472
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 14 people
- Sponsor
- Sanifit Therapeutics S. A.
End Stage Renal Disease
Elbow Pain in Hemodialysis Patients and Its Effect on Daily Living Activities of the Patients
The study will include the patients undergoing hemodialysis.
- Trial name
- NCT04188210
- Testing
- Presence of elbow pain in patients with end stage renal disease
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Namik Kemal University
Autosomal Dominant Polycystic Kidney Disease
Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease
This study will assess whether everolimus (RAD001) is effective in preventing cyst and kidney expansion as well as worsening of renal function in patients with ADPKD and whether the application of 5 mg/day everolimus as…
- Trial name
- NCT00414440
- Testing
- Everolimus
- Where
- 24 sites in Austria, France and 1 more
- Volunteers
- 431 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Renal Failure
Renal Sympathetic Modification in Patients With Chronic Renal Failure
The purpose of this study is to observe the incident of uremia and dialysis requirement after renal sympathetic modification using THERMOCOOL® catheter in patients with chronic renal failure, and evaluate safety and efficacy of…
- Trial name
- NCT01418560
- Testing
- renal sympathetic modification
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
End Stage Renal Disease
Theranova 400 Dialyzer In End Stage Renal Disease (ESRD) Patients
The study evaluates the efficacy and safety of the Theranova 400 dialyzer compared with Elisio-17 H dialyzer in end stage renal disease patients receiving hemodialysis treatment.
- Trial name
- NCT03257410
- Testing
- Theranova 400 dialyzer, Elisio-17H dialyzer
- Where
- 20 sites in United States
- Volunteers
- 172 people
- Sponsor
- Vantive Health LLC
Kidney Failure, Chronic, Resistance Training
Effect of PT on QL, FC, PWV and Biochemical Markers in CRF on Conservative Treatment
Introduction: Chronic Kidney Disease (CKD) is considered an important public health problem, with prevalence of 9.6% in our population.
- Conditions
- Kidney Failure, Chronic, Resistance Training, Treatment
- Trial name
- NCT01155297
- Testing
- Physical training, Stretching and metabolic exercises
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
End-stage Renal Disease
The Incidence of Extended-spectrum β-lactamase (ESBL) Klebsiella Pneumonia in Patient on Renal Replacement Therapy
The prevalence of ESBL Klebsiella pneumonia was higher in patient with renal replacement therapy.
- Trial name
- NCT01612182
- Testing
- renal replacement therapy
- Where
- South Korea
- Volunteers
- 1,289 people
- Sponsor
- Inje University
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