Clinical trials: End-Tidal Carbon Dioxide
Cholelithiases, Laparoscopic Cholecystectomy
"Comparison of of Volume-Controlled Ventilation and Pressure-Controlled Ventilation Modes in Laparoscopic Cholecystectomy"
This randomized controlled trial compares volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Cholelithiases, Laparoscopic Cholecystectomy, General Anaesthesia
- Trial name
- VCV VS PCV (NCT07709039)
- Testing
- Volume-Controlled Ventilation, Pressure Controlled Ventilation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mehreen Mirza
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Idiopathic Intracranial Hypertension
The Effects of MAP and EtCO2 on Venous Sinus Pressures
The purpose of this study is to further elaborate the role of both arterial blood pressure and end-tidal carbon dioxide concentration on measured venous pressures.
- Trial name
- NCT03867461
- Testing
- Venous Sinus Stenting, Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range), Adjustment to Mean Arterial Pressure (100-110 mmHg range)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Blood Volume Expansion
Ability of Changes in End Tidal Carbon Dioxide to Assess the Stroke Volume Effects of a Volume Expansion of 250ml of Crystalloid in the Operating Room
Volume expansion is the cornerstone of perioperative hemodynamic optimization. The main objective of volume expansion is to increase and to maximize stroke volume.
- Trial name
- REVCO2 (NCT03635307)
- Testing
- End Tidal Carbon Dioxide measure
- Where
- France
- Volunteers
- 115 people
- Sponsor
- University Hospital, Bordeaux
Ventilation, End-Tidal Carbon Dioxide
End-tidal Carbon Dioxide Monitoring in Low Tidal Volume Ventilation
In cases where there is no ventilation-perfusion problem, the end-tidal carbon dioxide (ETCO2) value is closely associated with partial arterial carbon dioxide pressure (PaCO2); therefore, the PaCO2 value can be estimated using…
- Trial name
- ETCO2 (NCT04281589)
- Testing
- if the ventilation parameter caused desaturation or hypercapnia we will change the parameter
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Brachial Plexus Injury
Changes in Optic Nerve Sheath Diameter in Response to Various Levels of End Tidal Carbon Dioxide Levels
Intracranial Pressure ( ICP ) monitoring is an essential component of traumatic brain injured ( TBI ) patients management. The clinical signs of raised ICP may be unreliable and may reflect relatively late cerebral…
- Trial name
- NCT02711774
- Testing
- ultrasonography
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Cognitive Dysfunction
The Influence of Ventilation on Perioperative Neurocognitive Disorders
This prospective study is designed to examine the influence of intra-operative ventilation on perioperative neurocognitive disorders in patients undergoing total hip arthroplasty.
- Trial name
- NCT04106869
- Testing
- Hyperventilation, Hypoventilation
- Where
- Belgium
- Sponsor
- Université Libre de Bruxelles
Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch
Physiological Dead Space and Intensive Care Mortality in Mechanically Ventilated Patients
This study investigates the relationship between physiological dead space and clinical outcomes, specifically mortality and discharge status, in adult patients receiving invasive mechanical ventilation in the intensive care unit…
- Conditions
- Invasive Mechanical Ventilation, Ventilation-Perfusion Mismatch, ICU Mortality, Critical Illness
- Trial name
- IRIS-MAP (NCT06963944)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Karadeniz Technical University
Circulatory Failure, Critical Illness
Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU
This prospective observational study evaluates whether monitoring changes in exhaled carbon dioxide (End-Tidal CO2 or EtCO2) during a "Passive Leg Raising" (PLR) test can reliably predict fluid responsiveness in critically ill…
- Conditions
- Circulatory Failure, Critical Illness, Hypovolemia
- Trial name
- NCT07304648
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Izmir Katip Celebi University
Anesthesia, General
The Effect of End-tidal Carbon Dioxide Level on the Optic Nerve Sheath Diameter in Pediatric Patients
Because the optic nerve is surrounded by the cerebrospinal fluid, increase / decrease in the intracranial pressure can be examined by an increase / decrease in the optic nerve sheath diameter (ONSD).
- Trial name
- NCT03988868
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Residual Cardiac Output During PVA-ECMO
Use of Exhaled Carbon Dioxyde for Monitoring the Native Cardiac Function During Mechanical Circulatory Support With Venoarterial By-pass in Intensive Care Unit
Cardiogenic shock, the most severe form of acute heart failure, is a critical situation where the body cells lack of oxygen because of cardiac dysfunction.
- Trial name
- CAPNOECMO (NCT03323268)
- Testing
- PetCO2 monitoring
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Montpellier
Postoperative Nausea and Vomiting
Comparison of Different EtCO2 Levels in Preventing Postoperative Nausea and Vomiting
We aimed to evaluate the different ETCO2 levels (with the help of ultrasonographic optic nerve sheath diameter) in preventing gynecological laparoscopic surgeons' postoperative nausea induced by intracranial pressure change due…
- Trial name
- NCT03472209
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Stroke
Ventilation Strategies, Anesthetic Techniques and Cerebral Oxygenation in the Beach Chair Position
The seated or "beach chair" position during surgery and general anesthesia decreases brain oxygen levels and can result in stroke. As such, poor neurological outcome following beach chair positioning is a growing concern.
- Trial name
- NCT01535274
- Testing
- Inspired oxygen fraction / end tidal carbon dioxide
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Michigan
Metabolic Acidosis, Diabetic Ketoacidosis
Diabetic Ketoacidosis Diagnosis and Management
This is the first and only study conducted on the use of capnography in children diagnosed with DKA to evaluate the initial clinical grading of DKA, monitor clinical improvement, and predict complications such as brain edema.
- Conditions
- Metabolic Acidosis, Diabetic Ketoacidosis, Brain Edema
- Trial name
- NCT06327737
- Testing
- Capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Akdeniz University
Cardiopulmonary Resuscitation, Echocardiography
Correlation Between End-tidal CO2 and Degree of Compression of Heart During CPR Measured by Ultrasound
Individual optimization of cardiopulmonary resuscitation (CPR) in real time may increase the success rate of the procedure. End-tidal CO2 (EtCO2) levels reflect cardiac output induced by CPR.
- Trial name
- NCT03852225
- Testing
- Intra-arrest echocardiography
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Emergency Medical Service of the Central Bohemian Region, Czech Republic
End Tidal CO2, CO2 Removal
A New and Innovative Method for CO2 Removal in Anesthetic Circuits: Replacing Chemical Granulate
CO2 removal is a mandatory part of modern anesthesia systems. Current chemical absorbers pose problems as the chemical granulate reacts not only with the CO2 but also the anesthetic drugs, producing organ toxic substances.
- Trial name
- NCT02195245
- Testing
- memsorb
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- DMF Medical Incorporated
COPD
End Tidal Carbon Dioxide Monitoring for Evaluating Changes of PaCO2 After Noninvasive Mechanical Ventilation in COPD
Sidestream end-tidal CO2 has been found to be closely correlated to PaCO2 especially when people have the stable hemodynamics and normal lung function.
- Trial name
- NCT01821365
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Anesthesia
The Effect of Pressure Support Ventilation on Spontaneous Breathing in Anesthetized Subjects
The aim of this prospective study is to determine the effect of pressure support ventilation (PSV) on minute alveolar ventilation (MAV) and end-tidal carbon dioxide (ETCO2) in anesthetized spontaneously breathing subjects by…
- Trial name
- NCT02385305
- Testing
- Pressure support ventilation by anesthesia machine (Apollo, Dräger)
- Sponsor
- Massachusetts General Hospital
Prehospital Resuscitation, End-Tidal Carbon Dioxide
End-Tidal CO2 (ETCO2) Trends in Out-of-Hospital Cardiac Arrest
The investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2…
- Conditions
- Prehospital Resuscitation, End-Tidal Carbon Dioxide, Cardiac Arrest, Out-Of-Hospital, Prehospital Emergency Medical Services
- Trial name
- NCT07632430
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- Office of the Medical Director for EMS in Oklahoma City and Tulsa
Septic Shock, Hypovolemia
Assessment of Fluid Responsiveness in Septic Shock Patients, Can End-tidal co2 Measurement Help?
Fluid therapy is important in patients with sepsis and septic shock. There are many invasive and non-invasive methods to assess fluid responsiveness in patients.
- Conditions
- Septic Shock, Hypovolemia, Sepsis
- Trial name
- NCT05557461
- Testing
- End-tifdal co2, systolic, diastolic blood pressure, ppv values and vci distensibility
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bozyaka Training and Research Hospital